Category: clinical study retractions

Authors retract PNAS paper suggesting silk stabilizes vaccines

PNASA PNAS paper that caught the media’s attention for suggesting that adding silk could stabilize vaccines and antibiotics has been pulled after the authors realized there were significant errors in the data analysis. 

According to the notice, the authors agreed to retract the 2012 paper; however, the corresponding author told us the authors did not think a retraction was required as, according to him, the conclusions remained valid.

The paper presented a solution to the long-standing problem that sensitive biological compounds such as vaccines and antibiotics begin to lose their effectiveness outside the recommended temperature range, and naturally biodegrade over time. The degradation process cannot be reversed, and may even speed up during transport or storage under less ideal temperatures.

Here’s the retraction notice: Continue reading Authors retract PNAS paper suggesting silk stabilizes vaccines

Two journals retracting papers from University of Malaya featuring widely criticized figures

The image that excited twitter: Figure 6 from the Scientific Reports paper
The image that excited Twitter

One journal has retracted a paper containing images that recently raised suspicions of obvious duplications, and another journal is planning to do the same.

Scientists first leveled accusations against the newly retracted paper in Scientific Reports, along with two others by the same researchers, earlier this month on Twitter. One other journal — PeerJ — has announced that it plans to retract one of the questioned papers, as well. The third paper, in Frontiers in Pharmacology, bears an expression of concern.

It was unusually quick action on the part of the journals, as well as the authors’ host institution, the University of Malaya, which announced last week the authors had manipulated figures in all three papers, along with one other.

Here’s today’s retraction notice from Scientific Reports for “Novel piperazine core compound induces death in human liver cancer cells: possible pharmacological properties:”

Continue reading Two journals retracting papers from University of Malaya featuring widely criticized figures

Journal flags paper over allegations it used competitors’ text, plasmids

MGGA journal has issued an expression of concern (EOC) for a paper on a common crop virus after the authors were accused of using competitors’ unpublished text and plasmids.

Investigations by the journal and the involved institutions — the University of the Witwatersrand in South Africa, where the paper’s authors are based, and North Carolina State University (presumably, where the accusing group is from) — were inconclusive, the notice states.

So the editor flagged “Sequences enhancing cassava mosaic disease symptoms occur in the cassava genome and are associated with South African cassava mosaic virus infection” with an EOC:

Continue reading Journal flags paper over allegations it used competitors’ text, plasmids

Dental paper pulled for “wrong content with serious consequences”

Clinical Oral InvestigationsAn article on how missing teeth affect chewing was — well, pulled — when someone noticed a few errors. The journal later published a corrected version.

The retraction for “Chewing ability in an adult Chinese population” appeared in Clinical Oral Investigations in 2012, but we’re sharing it with you now because the notice contains some remarkable language:

This article has been withdrawn due to wrong content with serious consequences such as danger to people’s health.

Last author Nico H.J. Creugers, who works at Radboud University Medical Center in the Netherlands, told us: 

Continue reading Dental paper pulled for “wrong content with serious consequences”

JAMA authors retract (and replace) paper about moves and kids’ mental health

JAMAJAMA authors have retracted — and replaced — a 2014 paper about the mental health effects of household moves on kids, after they found errors while completing an additional analysis.

The original paper concluded that in “families who moved out of high-poverty neighborhoods, boys experienced an increase and girls a decrease in rates of depression and conduct disorder,” according to a press release issued by the journal along with the paper (which also got some press attention from Reuters). But part of that conclusion is wrong.

The authors write in a notice for “Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence” that:

Continue reading JAMA authors retract (and replace) paper about moves and kids’ mental health

Nutrition researcher loses two more papers after misconduct findings come to light

R K Chandra, self-proclaimed father of nutritional immunology (from www.drrkchandra.com)
R K Chandra, self-proclaimed father of nutritional immunology (from www.drrkchandra.com)

The self-proclaimed “father of nutritional immunology,” Ranjit Kumar Chandra, has lost two more papers following the release of a misconduct investigation report by his former employer, Memorial University of Newfoundland (MUN).

The report was released last year after Chandra lost his libel suit against the Canadian Broadcasting Company (CBC). The newly retracted papers were both published in Nutrition Research. On one, the author is listed as “Amrit Jain,” who is allegedly Chandra, as well.

Here’s the retraction notice for the article by Amrit Jain: 

Continue reading Nutrition researcher loses two more papers after misconduct findings come to light

Figures questioned online were manipulated, says Malaysia investigation

The image that excited twitter: Figure 6 from the Scientific Reports paper
The image that set Twitter abuzz: Figure 6 from the Scientific Reports paper, in which every cell in each stage of cell death appeared to be an exact copy.

Many figures in four papers by a research team in Malaysia contain duplication or manipulation, a university committee has found, calling for multiple retractions.

We learned about issues with three of the papers, including one in Scientific Reports, earlier this week when they were the talk of Twitter. As journals issued expressions of concern, and an expert wondered how the papers passed peer review at all, the first author, a researcher at the University of Malaya (UM), denied allegations of duplication.

UM was alerted to allegations of misconduct in the Scientific Reports paper last Saturday, and according to a statement published today:

Continue reading Figures questioned online were manipulated, says Malaysia investigation

JAMA: No plan to retract article on fetal pain, despite outcry from anti-abortion activists

JAMAJAMA has announced it does not intend to retract a 2005 review article about fetal pain, despite requests from anti-abortion activists who claim it has been misused in debates about the procedure.

Earlier this month, JAMA told one anti-abortion critic that it would take a look at the paper, which suggested that fetuses can’t feel pain before the third trimester. Critics have argued that newer findings have shown pain sensation appears earlier in gestation, yet the 2005 data continue to be cited in the discussion around abortion. What’s more, critics have lamented that some of the authors failed to mention their ties to the abortion industry.

But in a letter sent yesterday to James Agresti, Howard Bauchner, Editor in Chief at JAMA and The JAMA Network, writes: Continue reading JAMA: No plan to retract article on fetal pain, despite outcry from anti-abortion activists

Images that raised eyebrows flagged by another journal; Malaysian gov’t investigates

Screen Shot 2016-06-15 at 9.17.15 AMMultiple investigations have been launched into allegations of blatant duplications by a research group in Malaysia.

Last week, users alleged on Twitter that three papers by the same team included pictures of cells that were copied and pasted. First author Nima Samie, affiliated with University of Malaya in Malaysia, denied the accusations — but both the Malaysian government and now two journals sees cause for further investigation.

Frontiers in Pharmacology published an expression of concern this morning:

Continue reading Images that raised eyebrows flagged by another journal; Malaysian gov’t investigates

Authors retract surgery study that claimed to be randomized but wasn’t

spine-coverThe authors of a study about spinal fusion surgery have retracted it after realizing the cohort study was described as a prospective, randomized trial. 

The last author told us he believed the incorrect wording was added to the paper — and the title — by accident. Even though he said the journal Spine suggested correcting it, the authors chose to retract the paper entirely.

The abstract of the study describes the design as a:

Prospective, randomized, controlled trial.

But according to the retraction notice for “Prospective, randomized, controlled trial of silicate-substituted calcium phosphate versus rhBMP-2 in a minimally invasive transforaminal lumbar interbody fusion,” the abstract was not accurate:

Continue reading Authors retract surgery study that claimed to be randomized but wasn’t