Category: clinical study retractions

Is the bulk of fMRI data questionable?

Anders Eklund
Anders Eklund, via Linköping University

Last week, a study brought into question years of research conducted using the neuroimaging technique functional magnetic resonance imaging (fMRI). The new paper, published in PNAS, particularly raised eyebrows for suggesting that the rates of false positives in studies using fMRI could be up to 70%, which may affect many of the approximately 40,000 studies in academic literature that have so far used the technique. We spoke to the Anders Eklund, from Linköping University in Sweden, who was the first author of the study. Continue reading Is the bulk of fMRI data questionable?

Should a paper be retracted if an author omits a conflict of interest?

s-cover-yvs1606A JAMA journal has quickly issued a correction for a 2016 paper after the author failed to mention several relevant conflicts of interest. Normally, we’d see this as a run-of-the-mill correction notice, but since we reported last week that a journal retracted a paper for omitting pharma funding, we got to wondering: Is failure to disclose a conflict of interest a retractable offense?

Guidelines from the Committee on Publication Ethics (COPE) do say that retractions are used for “failure to disclose a major competing interest likely to influence interpretations or recommendations.” But most of the time when we see corrections to the literature for such omissions, they’re corrections, not retractions.

On Friday, JAMA Ophthalmology issued a correction notice for an invited commentary published in April, which addressed two papers in the journal about melanoma of the eye (uveal melanoma). However, the original commentary failed to note that author Arun D. Singh at the Cleveland Clinic had some relevant conflicts to mention, as the notice explains: Continue reading Should a paper be retracted if an author omits a conflict of interest?

Authors who lost paper linking fecal transplants to obesity have another retracted

International Journal of ObesityAn obesity journal has retracted a study by authors who previously lost another paper that suggested a link between the fecal microbiome and obesity.

We first came across on the now-retracted paper in the International Journal of Obesity (IJO) in April when we reported on the authors’ other retraction in Diabetes. The 2014 paper had a corrigendum, published the same year, and also for image-related issues. Since then, however, the journal has pulled the IJO paper and its associated corrigendum at the request of the French National Institute of Agronomic Research (INRA) in Paris. Continue reading Authors who lost paper linking fecal transplants to obesity have another retracted

PLOS ONE pulls malaria study for “inappropriate manipulation” of figures

PLOS OnePLOS ONE has retracted a malaria paper after an institutional investigation found evidence the authors had manipulated multiple figures.

According to the notice, the authors’ institution — the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi, India — recommended the journal retract the paper.

Here’s the retraction notice, issued by PLOS ONE on June 30: Continue reading PLOS ONE pulls malaria study for “inappropriate manipulation” of figures

Crow’s feet filler study omitted pharma funding, gets retracted

JKMSA paper on a filler for eye wrinkles did not disclose that it was funded by a pharmaceutical company that produces the cosmetic.

The paper explicitly noted that the authors do not have any financial conflicts of interest, and that a government program supported the study. According to the journal, a reader alerted them to the conflict of interest.

The cooperate tie wasn’t a secret, though — one of the authors was listed as affiliated with the  company, Pharma Research Products, based in Korea.

Here’s the retraction notice for “A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial and Preclinical Animal Study to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet: A New Concept of Regenerative Filler:”

Continue reading Crow’s feet filler study omitted pharma funding, gets retracted

Vector wasn’t a gift after all, correction notes

CirculationA paper accidentally credited the wrong researcher with providing part of an experiment.

It turns out that one of the authors supplied an expression vector to a Circulation paper about the molecular underpinnings of atherosclerosis — not the outside researcher originally thanked in the acknowledgements section.

The correction notice to the paper makes the situation sound more mysterious than it appears to be:

Continue reading Vector wasn’t a gift after all, correction notes

Diabetes researcher logged 1 retraction, 3 correx, after PubPeer comments

Kathrin Maelder
Kathrin Maedler

A journal has retracted a paper by a leading diabetes researcher — who has also issued three corrections — after questions about her research were raised on PubPeer.

Kathrin Maedler — who works at the University of Bremen in Germany — corrected another paper in 2014. All of the notices are dated from 2015, and all describe issues with figures.

The ongoing comments have led Maedler to carefully look through her original data, according to a statement she emailed us: Continue reading Diabetes researcher logged 1 retraction, 3 correx, after PubPeer comments

Sixth retraction appears for bone researcher due to “extensive self-plagiarism”

cov150hA bone researcher in Japan has logged his sixth retraction, after acknowledging he duplicated substantial portions of a 2011 paper and added “honorary” co-authors.

The retraction, in Parkinsonism & Related Disorders, follows five others for Yoshihiro Sato, including one from JAMA, some of which were pulled over concerns regarding authorship and data integrity. The latest retraction duplicated text from another 2005 paper that was itself retracted last year, both for duplicating from this newly retracted paper and for “concerns about the underlying data.”

Sato — who is listed at Mitate Hospital on the paper — told the journal he takes full responsibility.

Here’s the retraction notice: Continue reading Sixth retraction appears for bone researcher due to “extensive self-plagiarism”

Unwitting co-author requests retraction of melatonin paper

Screen Shot 2016-06-08 at 10.54.58 PMNine years ago, a well-known pharmacologist hosted a researcher from another university in his lab. On a Saturday night last September, he learned while surfing Google Scholar that they had published a paper together.

Marco Cosentino, who works at the University of Insubria in Italy, know that Seema Rai, a zoologist at Guru Ghasidas Vishwavidyalaya in India, had collected data during during her six months in his lab, but had warned her they were too preliminary to publish. She published the data — on melatonin’s role in immunity — anyway, last summer in the Journal of Clinical & Cellular Immunology, listing Cosentino as the second author.

The day after he discovered the paper, Cosentino sent an email to the editor in chief of the journal, Charles Malemud, explaining why he did not approve of the publication:

Continue reading Unwitting co-author requests retraction of melatonin paper

HIV paper pulled for lack of consent, errors

AIDS JournalA researcher failed to obtain proper consent from HIV patients included in his study about risky sexual behavior, according to the journal that retracted his paper.

The study, based on interviews with 154 men and women living with HIV, concluded that experiencing negative life events correlated with risky sexual behavior. But although the author claimed to have complied with the journal’s standard of consent, the journal disagreed, and retracted the paper in 2014 (we think this case is interesting enough to share with you now). What’s more, according to the journal, the paper contains errors that invalidate its conclusions.

Here’s the notice:

Continue reading HIV paper pulled for lack of consent, errors