The U.S. Office of Research Integrity (ORI) announced today that a former graduate student committed research misconduct — nearly two years after his institution stripped him of his degree.
The ORI concluded that Shiladitya Sen committed misconduct in a PNAS paper (retracted six months ago), his PhD thesis, a poster presentation, and two grant applications to the National Institutes of Health (NIH). Sen has agreed not to seek federal funding for three years.
A spokesperson for The Ohio State University (OSU), where Sen was based, told us its investigation wrapped up in Spring 2016, and Sen’s PhD was revoked that June. It’s not clear why it took two years for the ORI to issue its own finding; the ORI did not immediately respond to requests for comment.
The former researcher at the University of Texas MD Anderson Cancer Center swapped her own blood samples for those taken from 98 human subjects. The misconduct affects two grant progress reports and two papers; one paper has already been retracted, and the former “research interviewer” — Maria Cristina Miron Elqutub — has agreed to correct or retract the other.
Adel El-Naggar, a co-author on both of the papers also based at the University of Texas MD Anderson Cancer Center, told Retraction Watch:
In 2009, a university announced a prominent researcher in the field of protein crystallography had likely fabricated nearly a dozen protein structures. Nine years later, the U.S. Office of Research Integrity (ORI) has upheld the results — and announced a relatively long sanction, by the agency’s standards.
Today, the ORI placed a 10-year ban on Federal funding for H.M. Krishna Murthy, a former research associate professor at the University of Alabama at Birmingham (UAB), noting he “falsified and/or fabricated” research in nine papers and multiple structures added to a widely used database. Four of the papers have already been retracted; two others have been flagged with an expression of concern by the journal. Three remain otherwise intact.
The announcement was a long time coming — after the ORI provided Murthy with its initial finding and proposed sanctions, he appealed. On January 19, 2018, and Administrative Law Judge declined to move forward with the appeal, allowing the agency to proceed. Today’s finding was accompanied by a rare message from the interim office of the director, Wanda Jones, in which she notes today’s announcement:
When the Proceedings of the National Academy of Sciencesretracted a gene therapy paper in December, it declared that some of the data had been falsified and mentioned a research misconduct investigation. But the notice said nothing about who was responsible.
Via a public records request, Retraction Watch has obtained investigation documents from the University of Florida, which show the focus had been narrowed down to two of the paper’s three co-first authors. But the investigation committee didn’t assign blame to either one. According to their final report, dated Oct. 24, 2016:
there was not enough direct evidence to either implicate or exonerate either of these individuals.
An investigation by Kyoto University in Japan has found a researcher guilty of falsifying all but one of the figures in a 2017 stem cell paper.
Yesterday, Kyoto Universityannounced that the paper’s first author, Kohei Yamamizu, had fabricated and falsified datain the Stem Cell Reportspaper. According to the investigation report, none of the other authors were involved in the data manipulation.
Yamamizu works at the Center for iPS cell Research and Application (CiRA) at Kyoto University, directed by Shinya Yamanaka, a Nobel Prize winner for his pioneering work in stem cell biology.
A spokesperson for the journal told us that the authors disclosed the problems last week and Stem Cell Reports will be retracting the paper, published last February.
A researcher has retracted a 2009 chemistry paper after discovering that a figure had been “inappropriately edited.”
According to the journal, a reader brought the images in question in Figure 1 to the editors’ attention last September.Timothy P. Lodge, distinguished professor at the University of Minnesota in Minneapolis — and editor of Macromolecules through December 2017 —told Retraction Watch:
A university investigation has found falsified data in a 2011 paper about the side effects of a virus commonly used in gene therapy.
The authors are retracting the paper, but one co-author told Retraction Watch they stand by their main conclusions. According to Roland Herzog, a professor at the University of Florida (UF) College of Medicine and a co-author of the paper, the falsified data were related to a minor part of the paper.