Category: erroneous data

Sperm paper impaired by “corporate company” analysis

2.coverWithout a certain protein, mouse sperm have motility disorders. That’s the conclusion of a paper that has itself been stopped — by errors in the data analysis, carried out by a third-party company.

The retraction note pins the analysis, which led to faulty data, on a “corporate company.” Aside from the companies that sell the kits used for substrates, assays, and detection, there’s only one company mentioned in the paper:

Generation of the mouse model was performed by the Cyagen Company (Guangzhou, China)

However, a representative of Cyagen says it does not offer the type of analysis described by the retraction note.

Here’s the full retraction note for the 2015 paper in Biology of Reproduction (which is paywalled — tsk, tsk):
Continue reading Sperm paper impaired by “corporate company” analysis

Poll: If authors don’t address mistakes, is that misconduct?

cover_natureIn an interesting letter printed in today’s Nature, biologists Sophien Kamoun and Cyril Zipfel suggest that “failure by authors to correct their mistakes should be classified as scientific misconduct.”

They note that this policy is already in place at their institute, The Sainsbury Laboratory (TSL).

We contacted Kamoun to ask what constituted a mistake, given that numerous papers have received queries, such as on sites like PubPeer, but it’s not clear whether those are legitimate mistakes. He told us: Continue reading Poll: If authors don’t address mistakes, is that misconduct?

Doctor suspended in UK after faking co-authors, data

Screen Shot 2016-02-24 at 11.04.56 AMA doctor in Manchester, UK has received a year’s suspension by the Medical Practitioners Tribunal Service.

Gemina Doolub admitted that she fabricated research data and submitted papers without the knowledge of her co-authors, including faking an email address for a co-author, a news story in the BMJ reports. The research in question was part of two retractions that Doolub received in 2013, one of which we covered at the time.

Doolub’s research examined ways to treat and avoid microvascular obstruction — that is, blocked arteries. Doolub did the work while at Oxford.

“Intracoronary Adenosine versus Intravenous Adenosine during Primary PCI for ST-Elevation Myocardial Infarction: Which One Offers Better Outcomes in terms of Microvascular Obstruction?” was published in International Scholarly Research Notices Cardiology and has not yet been cited, according to Thomson Reuters Web of Science.

As the BMJ reports, in that paper,

Continue reading Doctor suspended in UK after faking co-authors, data

Why publishing negative findings is hard

Jean-Luc Margot
Jean-Luc Margot

When a researcher encountered two papers that suggested moonlight has biological effects — on both plants and humans — he took a second look at the data, and came to different conclusions. That was the easy part — getting the word out about his negative findings, however, was much more difficult.

When Jean-Luc Margot, a professor in the departments of Earth, Planetary & Space Sciences and Physics & Astronomy at the University of California, Los Angeles, tried to submit his reanalysis to the journals that published the original papers, both rejected it; after multiple attempts, his work ended up in different publications.

Disagreements are common but crucial in science; like they say, friction makes fire. Journals are inherently disinterested in negative findings — but should it take more than a year, in one instance, to publish an alternative interpretation to somewhat speculative findings that, at first glance, seem difficult to believe? Especially when they contain such obvious methodological issues such as presenting only a handful of data points linking biological activity to the full moon, or ignore significant confounders?

Margot did not expect to have such a difficult experience with the journals — including Biology Letters, which published the study suggesting that a plant relied on the full moon to survive: Continue reading Why publishing negative findings is hard

Authors used wrong dataset in study on shock therapy, exercise in depression

J psych resA psychiatric journal has pulled a 2014 paper that found electroconvulsive therapy and exercise helped people with depression, after the authors determined they had mistakenly analyzed the wrong data.

According to the retraction notice from the Journal of Psychiatric Research, the researchers had “erroneously analyzed” data from a previous study they had published the year before.

Here’s more from the note for “Electroconvulsive therapy and aerobic exercise training increased BDNF and ameliorated depressive symptoms in patients suffering from treatment-resistant major depressive disorder:” Continue reading Authors used wrong dataset in study on shock therapy, exercise in depression

Data irregularities force author to retract three solar cell papers

no spine minimum. full size. Editor: Jon JEM: Esther RTP: Bryan Nolte TOC image

An engineer has retracted three papers on a method for making nanoscale materials that are useful in solar cells.

The papers, all published in ACS Applied Materials & Interfaces, contain irregularities in data, and one includes images “which have been published elsewhere and identified with different samples,” according to the note.

The first author on all three papers is Khalid Mahmood, who — according to the bio from a talk he gave last year on efficient solar cells — is currently a postdoc at King Abdullah University of Science and Technology in Saudi Arabia. He did the work in the retracted papers while a student at the Korea Advanced Institute of Science and Technology, where, according to the bio, he completed his PhD in two years.

Here’s the retraction note for the first paper (which also contains a typo in the title — “electrospay”)

Continue reading Data irregularities force author to retract three solar cell papers

Makeup use linked to testosterone levels? Not so fast, says retraction

Psych SciA psychology journal is retracting a 2015 paper that attracted press coverage by suggesting women’s hormone levels drive their desire to be attractive, after a colleague alerted the last author to flaws in the statistical analysis.

The paper, published online in November, found women prefer to wear makeup when there is more testosterone present in their saliva. The findings were picked up by various media including Psychology Today (“Feeling hormonal? Slap on the makeup”), and even made it onto reddit.com.

However, upon discovering a problem in the analysis of the data, the authors realized that central finding didn’t hold up, according to Psychological Science‘s interim editor, Stephen Lindsay: Continue reading Makeup use linked to testosterone levels? Not so fast, says retraction

Letter calls for retraction of yoga weight loss paper

IntJYoga_2016_9_1A paper concluding that a specific series of yoga poses is effective at promoting weight loss in obese women has a call for retraction in a letter to the editor of the International Journal of Yoga. 

The study followed 87 women for 8 weeks as they completed a regular routine of  yoga, circuit training, or walking on a treadmill. “Suryanamaskar: An equivalent approach towards management of physical fitness in obese females” concludes that

All three methods were effective in weight and physical fitness management.

But a group of heath researchers at the University of Alabama at Birmingham led by David Allison failed to replicate the statistical tests on some of the data. In a recent letter to the editor, “Unsubstantiated conclusions from improper statistical design and analysis of a randomized controlled trial,” they express skepticism about the paper’s claims, and ask the journal to retract it:

Continue reading Letter calls for retraction of yoga weight loss paper

“Innocent mistake” leads to bioethics article retraction

jbiA July article that incorrectly called out nine leading bioethics journals for their lack of availability to researchers in low- and middle-income countries is being pulled after editors of the indicted journals refuted the allegations.

The last author on the article, published in the Journal of Bioethical Inquiry, told us an “innocent mistake” and difficulty navigating a website led the authors to incorrectly note that nine journals had not made their contents available through the World Health Organization’s Health InterNetwork Research Initiative database (HINARI), which gives bioethicists who live in low- and middle-income countries access to research articles either free of charge or at reduced cost. The authors argued that the mistake didn’t affect the paper’s conclusions, but the journal disagreed, and opted to pull the paper entirely.

After searching through the database, first author Subrata Chattopadhyay mistakenly determined that the journals had not made their contents available through HINARI, when in fact they were listed but on a different part of the website.

Even with the error, the authors maintain that their conclusions remain sound and that the field is shaped by a “hegemony of Western bioethics.” Continue reading “Innocent mistake” leads to bioethics article retraction

Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

cov150hAn investigation into a paper that compared infection rates from different types of central lines started with an allegation about a failure to disclose a conflict of interest, and ended up concluding that the science in the paper was flawed.

The 2013 paper — now retracted by the American Journal of Infection Control — suggested a particular kind of connector between the catheter and the patient could reduce some of the notoriously deadly bloodstream infections associated with the procedure, according to a press release that publicized the work. But last year, the journal issued an expression of concern for the paper, noting there were questions about the data. The retraction note reveals an investigation at Georgia Regents University — now known as Augusta University — started looking into undisclosed conflicts of interest in the paper, and ultimately concluded the science was flawed.

Here’s the retraction note, published in the January 1st 2016 issue of the journal, for “Comparison of central line-associated bloodstream infection rates when changing to a zero fluid displacement intravenous needleless connector in acute care settings”

Continue reading Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too