Nature: No plans to change wording of STAP retractions

cover_nature (2)Despite acknowledging in its own pages that two recent high-profile retraction notices turned out to not tell the whole story, Nature will not be updating the original retraction notices, the journal tells us.

We checked in with Nature after it published two Brief Communications Arising regarding two high-profile retractions of papers describing a new method of reprogramming cells to a pluripotent state. (This method is also known as stimulus-triggered acquisition of pluripotency, or STAP.)

We were particularly intrigued by the journal’s plans for the retractions, published in 2014, when an editorial in the September 23 issue about the new BCAs (here and here) suggested the wording of the notices might be problematic: Continue reading Nature: No plans to change wording of STAP retractions

Author appeals retraction after co-authors dispute Nature Comm paper

nature comm

Two weeks after Nature Communications published a paper on asymmetric cell division in July, it posted a retraction notice saying the paper was submitted “without the knowledge or consent” of all but the corresponding author.

The following day the journal “amended” the retraction note to include the initials of the corresponding author, Aicha Metchat, then based at European Molecular Biology Laboratory in Heidelberg, Germany.

The final notice for “An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes” reads:

Continue reading Author appeals retraction after co-authors dispute Nature Comm paper

Animal welfare breach prompts Nature correction

cover_nature (1)A 2011 letter to Nature from Harvard researchers received its second correction today, this time after discovering the researchers conducted experiments in which mice may have “experienced more pain and suffering than originally allowed for.”

That quote comes from an accompanying editorial in the journal, a rare move for a correction to a 2011 letter. But it’s an unusual correction, for a letter that found that a component of a pepper plant appeared to selectively kill cancer cells, leaving healthy cells relatively unscathed.

Here’s the first paragraph from the detailed correction notice, published today: Continue reading Animal welfare breach prompts Nature correction

Stem cell researcher Jacob Hanna’s correction count updated to 10

Jacob Hanna
Jacob Hanna

Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.

The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.

First up, a correction to a Cell paper on which Hanna is the first author:

Continue reading Stem cell researcher Jacob Hanna’s correction count updated to 10

NSF investigation of high-profile plant retractions ends in two debarments

Jorge Vivanco
Jorge Vivanco

A nearly ten-year-long series of investigations into a pair of plant physiologists who received millions in funding from the U.S. National Science Foundation has resulted in debarments of less than two years for each of the researchers.

The NSF Office of Inspector General recently posted its close-out report on its decision and a review of the University’s investigation, which had recommended a total of eight retractions or corrections. Although the investigator’s names have been redacted, the text of retractions and corrections quoted in the report corresponds to papers by Continue reading NSF investigation of high-profile plant retractions ends in two debarments

Corrections (and one EoC) propagate for distinguished plant biologist, Olivier Voinnet

Olivier Voinnet
Olivier Voinnet

There may be some deeply rooted issues in the work of high-profile plant biologist Olivier Voinnet, biology department research director at ETH in Zurich. Corrections have continued to pile up months after his work was hit with a barrage of criticism on PubPeer. We’ve tracked a total of seven corrections over the past five months (not including the April retraction of a 2004 paper in The Plant Cell). One of the corrected papers also received an Expression of Concern this week.

Collectively, the corrected papers have accumulated more than 1200 citations.

In January, Voinnet said he planned to correct multiple papers, after receiving “an anonymous email.”

One of the recent corrections we found is for a 2003 article in The Plant Journal, “An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus,” which details using proteins from a tomato virus to help alter gene expression. The study has been cited 862 times, according to Thomson Scientific’s Web of Knowledge. Here’s the correction notice, posted June 8:

Continue reading Corrections (and one EoC) propagate for distinguished plant biologist, Olivier Voinnet

Oncogene to retract breast cancer paper following years-old misconduct investigation

Oncogene is retracting a 2010 paper on the molecular details of breast cancer cells as they undergo metastasis following an investigation that discovered the first author had committed misconduct.

The thing is, the investigation concluded in 2012, and the paper — “miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers” — isn’t being retracted until next week.

According to Lucinda Haines, senior publishing manager at Nature Publishing Group, the paper will be retracted June 29.

We heard from Iris Behrmann, Head of the Life Sciences Research Unit at the University of Luxembourg:

Continue reading Oncogene to retract breast cancer paper following years-old misconduct investigation

Columbia biologists “deeply regret” Nature retraction, after postdoc faked 74 panels in 3 papers

natureA team of Columbia University biologists has retracted a 2013 Nature paper on the molecular pathways underlying Alzheimer’s disease, the second retraction from the group after a postdoc faked data.

An April report from the Office of Research Integrity (ORI) found the a first author, former Columbia postdoc Ryousuke Fujita, responsible for “knowingly and intentionally fabricating and falsifying research in seventy-four (74) panels” in three papers: a 2011 Cell paper retracted in 2014, an unpublished manuscript, and this now-retracted Nature paper, “Integrative genomics identifies APOE e4 effectors in Alzheimer’s disease.”

The paper was touted in a Columbia University Medical Center press release as identifying “key molecular pathways” leading to late-onset Alzheimer’s disease. The paper fingered two potential molecular drug targets, as well.

Here is the full retraction notice: Continue reading Columbia biologists “deeply regret” Nature retraction, after postdoc faked 74 panels in 3 papers

Nature retraction, resignation result after lung cancer cell lines “cannot be those specified”

cover_natureUpon realizing they had experienced a case of mistaken cell-line identity, the authors of a 2014 Nature paper on lung cancer think “it prudent to retract pending more thorough investigation,” as they explain in a notice published Wednesday.

The problem seems to stem from more than just honest error, according to corresponding author Julian Downward, a scientist at the Francis Crick Institute in the UK.

In a 1,215 word statement, sent to us via the Director of Research Communications and Engagement at Cancer Research UK, which funds Downward’s research, Downward told us the backstory not presented in the journal’s retraction note:

Continue reading Nature retraction, resignation result after lung cancer cell lines “cannot be those specified”

“Significant concerns” and formal investigation unwind Nature Nanotech sequencing paper

NatureNanoFollowing “significant concerns” raised by outside researchers and a formal university investigation, a group of authors in Taiwan has retracted a Nature Nanotechnology paper on DNA sequencing after they “could not reproduce the results of the work,” or even provide “a complete set of raw data for the original experiments.”

The paper, “DNA sequencing using electrical conductance measurements of a DNA polymerase,” describes a technology to sequence single DNA molecules — a technique that the authors, all based at National Chiao Tung University in Taiwan, suggest could be used to “cheaply and quickly” sequence DNA.

Concerns about the paper’s data were first raised in May 2013 by the community, according to an editorial from the journal. Then, the journal asked the university to investigate, says “Notes on a retraction”: Continue reading “Significant concerns” and formal investigation unwind Nature Nanotech sequencing paper