Category: NAS

Journals flag two papers by prominent researcher — who is also on trial for domestic abuse

Adeel Safdar was once a rising star in the field of kinesiology. After completing his doctorate degree at McMaster University in Canada, working with one of the titans of his field, Safdar took a postdoc at Harvard, then accepted a newly created chair position at another university in Ontario.

That all came crashing down last year, when Safdar went on trial in Canada, accused of horrifically abusing his wife. Over the course of the trial, allegations arose about his research, prompting two journals to flag papers he co-authored with his former mentor, Mark Tarnopolsky.

Tarnopolsky — author of more than 400 papers, which have collectively been cited more than 17,000 times, according to Clarivate Analytics’ Web of Science — told Retraction Watch:

Continue reading Journals flag two papers by prominent researcher — who is also on trial for domestic abuse

PNAS wouldn’t let authors cite unpublished manuscript. Now, it admits it was wrong.

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When researchers submitted a paper about a type of microparticle to PNAS, they wanted to give credit where it was due, and cite an unpublished manuscript that helped guide their work. But the journal’s policy forbid citing unpublished work, and the reference was removed before publication. Now, concerns from the authors of that unpublished work have prompted the journal to have a change of heart.  

Continue reading PNAS wouldn’t let authors cite unpublished manuscript. Now, it admits it was wrong.

Caught Our Notice: “The first author cut the thermoprinter paper printout into pieces and reassembled them”

Title: A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins

What Caught Our Attention: Here’s a cut-and-paste issue that gave us pause. The authors of an 18-year-old paper in PNAS corrected it after realizing some bands in a figure were duplicated (an issue raised on PubPeer one year ago). It turns out, the first author had cut the paper into pieces and reassembled them to present the blots in the “desired order,” and some had become duplicated by mistake. The overall results were unaffected, so the journal swapped the image with a corrected version. Continue reading Caught Our Notice: “The first author cut the thermoprinter paper printout into pieces and reassembled them”

UCSF-VA investigation finds misconduct in highly cited PNAS paper

PNAS has corrected a highly cited paper after an investigation found evidence of misconduct.

The investigation—conducted jointly by the University of California, San Francisco, and the San Francisco Veterans Administration Medical Center—uncovered image manipulation in Figure 2D, which “could only have occurred intentionally.” The institutions, however, could not definitively attribute the research misconduct to any individual.

According to the notice, the UCSF-VA committee determined that a correction to the 2008 PNAS paper—which explores the genetic underpinnings of prostate cancer—was “appropriate,” and the authors have now replaced the problematic figure with a corrected version. The 2008 paper has been cited 630 times, according to Clarivate Analytics’ Web of Science.

A spokesperson for PNAS told Retraction Watch: Continue reading UCSF-VA investigation finds misconduct in highly cited PNAS paper

Caught Our Notice: Voinnet co-author issues another correction

Title: AtsPLA2-α nuclear relocalization by the Arabidopsis transcription factor AtMYB30 leads to repression of the plant defense response

What Caught Our Attention:  A previous collaborator with high-profile plant biologist Olivier Voinnet (who now has eight retractions) has issued an interesting correction to a 2010 PNAS paper. Susana Rivas is last author on the paper, the correction for which notes some images were duplicated, and others were “cropped and/or stretched to match the other blots.” Rivas is currently a group leader at The Laboratory of Plant-Microbe Interactions (LIPM), “a combined INRA-CNRS Research Unit.” Continue reading Caught Our Notice: Voinnet co-author issues another correction

Overlooked virus “generated a mess,” infected highly cited Cell, PNAS papers

When Alexander Harms arrived at the University of Copenhagen in August 2016, as a postdoc planning to study a type of antibiotic resistance in bacteria, he carried with him a warning from another lab who had recruited him:

People said, “If you go there, you have to deal with these weird articles that nobody believes.”

The papers in question had been published in the Proceedings of the National Academy of Sciences in 2011 and Cell in 2013. Led by Kenn Gerdes, Harms’s new lab director, the work laid out a complex chain of events that mapped out how an E. coli bacterium can go into a dormant state, called persistence, that allows it to survive while the rest of its colony is wiped out.

Despite some experts’ skepticism, each paper had been cited hundreds of times. And Harms told us:

I personally did believe in the published work. There had been papers from others that kind of attacked [the Gerdes lab’s theory], but that was not high-quality work.

But by November 2016, Harms figured out that the skeptics had been right.  Continue reading Overlooked virus “generated a mess,” infected highly cited Cell, PNAS papers

Florida investigation can’t ID culprit who falsified data in retracted PNAS paper

When the Proceedings of the National Academy of Sciences retracted a gene therapy paper in December, it declared that some of the data had been falsified and mentioned a research misconduct investigation. But the notice said nothing about who was responsible.

Via a public records request, Retraction Watch has obtained investigation documents from the University of Florida, which show the focus had been narrowed down to two of the paper’s three co-first authors. But the investigation committee didn’t assign blame to either one. According to their final report, dated Oct. 24, 2016:

there was not enough direct evidence to either implicate or exonerate either of these individuals.

Over the course of the formal investigation, which lasted from early August to late October 2016,  the committee was able to determine that data in the PNAS paper had been falsified. However, it said: Continue reading Florida investigation can’t ID culprit who falsified data in retracted PNAS paper

Stanford prof plans to drop $10m suit against PNAS and critic

Mark Jacobson

A professor who is suing a journal publisher and critic for defamation has announced he plans to drop the case.

Yesterday, Stanford University professor Mark Jacobson announced on Twitter that he plans to “voluntarily dismiss the lawsuit” he filed last year in the District of Columbia, in which he alleged he was defamed when the Proceedings of the National Academy of Sciences published a paper critical of his research on the future of renewable energy. Continue reading Stanford prof plans to drop $10m suit against PNAS and critic

They thought they might solve the world’s energy problems. Then they realized they were wrong.

Frederick MacDonnell

Researchers are retracting a 2016 PNAS paper that described a way to create gasoline-like fuels directly from carbon dioxide in the atmosphere.

Senior author Frederick MacDonnell, a professor at the University of Texas at Arlington (UTA), told us he originally thought his team had made a preliminary breakthrough that might “solve the world’s energy problems.” Instead, he said:

It was an elaborate trap we fell into.

In a retraction notice that contains more information than we usually see, MacDonnell and his co-authors wrote: Continue reading They thought they might solve the world’s energy problems. Then they realized they were wrong.

University finds falsified data in PNAS gene therapy paper, authors retract

A university investigation has found falsified data in a 2011 paper about the side effects of a virus commonly used in gene therapy.

The authors are retracting the paper, but one co-author told Retraction Watch they stand by their main conclusions. According to Roland Herzog, a professor at the University of Florida (UF) College of Medicine and a co-author of the paper, the falsified data were related to a minor part of the paper.

The paper, “Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy,” was published in the Proceedings of the National Academy of Sciences (PNAS) in March 2011. All authors were affiliated with UF at the time; the handling editor, Kenneth Berns, is an emeritus professor at UF. The paper has been cited 50 times, according to Clarivate Analytics’ Web of Science. Continue reading University finds falsified data in PNAS gene therapy paper, authors retract