Third retraction for former rising star found guilty of misconduct

A once-prominent researcher in the field of infectious disease — who was found guilty of misconduct last year— has had a third paper retracted, a 2006 article in PNAS.

Last year, the University of Dundee in Scotland found that Robert Ryan had committed research misconduct, which included misrepresenting clinical data and duplicating images in a dozen different publications. After a failed attempt to appeal the decision, Ryan resigned.

In April, we covered Ryan’s first two retractions – a 2012 paper in Molecular Microbiology, which cited image errors, and a 2011 paper in Journal of Bacteriology, which cited image duplication.

Now, PNAS has retracted a 2006 paper, which cites potential image duplication as well as “irregularities” in the data.

Here’s the retraction notice for “Cell–cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover:”

Continue reading Third retraction for former rising star found guilty of misconduct

Researchers retract a paper when they realize they had sequenced the wrong snail’s genome

Researchers in China thought they had sequenced the genomes of two snails that help transmit diseases to other species — an important first step to stopping the spread. But their hopes were soon dashed after they realized they had misidentified one of the snails.

The researchers published their findings earlier this year in the journal Parasites & Vectors. In the paper, the authors stressed that understanding the genetic makeup of these molluscs is important because many “freshwater snails are intermediate hosts for flatworm parasites and transmit infectious diseases” to humans and other animals. They also acknowledged that identifying snail species from their appearance alone can be tricky. Continue reading Researchers retract a paper when they realize they had sequenced the wrong snail’s genome

“The article must be retracted:” Journal pulls prostate cancer study

A 2016 paper exploring the biology of prostate cancer has been retracted due to figure manipulation.

According to the retraction notice, a reader contacted the journal Clinical Cancer Research in late 2016 with concerns that similar bands appeared multiple times in two images. The editors asked the paper’s corresponding author, Shahriar Koochekpour, about the issue and requested the raw data for the figures. But Koochekpour, based in the Departments of Cancer Genetics and Urology at Roswell Park Cancer Institute in Buffalo, New York, at the time of the study, could not locate the raw data.

Since the lab did not have raw data from such a relatively recent paper, the editors reached out to the research integrity officer at Roswell Park Cancer Institute to investigate. Indeed,  the research integrity officer contacted confirmed that two figures were problematic, and requested the paper be retracted.

Here’s the rather detailed retraction notice, published in July 2017, for “GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models:” Continue reading “The article must be retracted:” Journal pulls prostate cancer study

The three-year delay: Journal finally retracts paper based on made-up data

Three years after an investigation revealed a 2013 paper was based on fraudulent data, a journal has finally retracted it.

The paper, published in Journal of Hazardous Materials, was one of seven articles by a team at the Institute of Microbial Technology (IMTECH) in Chandigarh, India that contain fabricated data, according to an investigation by the Council of Scientific and Industrial Research in New Delhi. (IMTECH is part of the Council of Scientific and Industrial Research.) Although it took one journal years to take action, another still has not retracted one of the seven flagged papers. Continue reading The three-year delay: Journal finally retracts paper based on made-up data

Publisher won’t retract two papers, despite university’s request

Jens Förster

Jens Förster, a high-profile social psychologist, has agreed to retract multiple papers following an institutional investigation — but has also fought to keep some papers intact. Recently, one publisher agreed with his appeal, and announced it would not retract two of his papers, despite the recommendation of his former employer.

Last month, the American Psychological Association (APA) announced it would not retract two papers co-authored by Förster, which the University of Amsterdam had recommended for retraction in May, 2015. The APA had followed the university’s advice last year and retracted two other papers, which Förster had agreed to as part of a settlement with the German Society for Psychology (DGPs). But after multiple appeals by Förster and his co-authors, the publisher has decided to retain the papers as part of the scientific record.

Many voices contributed to the discussion about these two papers — in November, 2016, the University of Amsterdam announced it was rejecting the appeal by another co-author on both papers, Nira Liberman, based at Tel Aviv University in Israel. The following month, Tel Aviv University announced that it believed the articles should not be retracted, based on its own internal review.

The APA reviewed the various recommendations, according to last month’s announcement:

Continue reading Publisher won’t retract two papers, despite university’s request

Newspaper series prompts CDC to correct paper on Legionnaire’s disease

Post-publication peer review isn’t just for scientists. Newspaper reporters can help correct the scientific record, too.

The U.S. Centers for Disease Control and Prevention (CDC) has corrected a journal article on Legionnaire’s disease after the Pittsburgh Post-Gazette revealed what seems to be efforts by the researchers to misrepresent their data.

In a series of articles last December, the newspaper raised questions about the CDC’s actions in the aftermath of outbreaks in 2011 and 2012 of Legionnaire’s that sickened 22 veterans, killing six. The Post-Gazette obtained emails from CDC scientists that appeared to reveal their disdain for the sterilization method the hospital had been using to suppress the growth of Legionella bacteria. That method, a copper-silver system, is widely considered to be effective. But according to the newspaper, the CDC investigators were so critical of the copper-silver disinfectant technology that the VA ultimately switched to a system based on chlorine.   Continue reading Newspaper series prompts CDC to correct paper on Legionnaire’s disease

“The data have spoken:” Controversial NgAgo gene editing study retracted

The author of a 2016 paper describing a potentially invaluable lab tool has retracted it, following heavy criticism from outside groups that could not reproduce the findings.

The paper had already been tagged with an Expression of Concern by the journal, Nature Biotechnology, which included data from multiple groups casting doubt on the original findings. Although the authors, led by Chunyu Han at Hebei University of Science and Technology in China, produced data to support their original findings, the journal has concluded — following “feedback from expert reviewers” — that the additional data “are insufficient to counter the substantial body of evidence that contradicts their initial findings,” according to an editorial released today:

Continue reading “The data have spoken:” Controversial NgAgo gene editing study retracted

Author admits to manipulating more than a dozen images in 2013 paper

A former graduate student at the University of Hong Kong confessed to making “inappropriate modifications” to several figures in a 2013 paper in the Journal of Biological Chemistry (JBC).

According to the retraction notice, the authors identified issues in 13 images while reviewing the data; the paper’s first author, Yingying Lu, copped to manipulating the figures. Even though “these modifications did not change the results or interpretations of this work,” the authors requested the paper be retracted.

The paper’s corresponding author, Jainbo Yue, previously based at the University of Hong Kong and now at the City University of Hong Kong, had nothing to add to the retraction notice, and told us that a “third person” is repeating the key experiments.

Here’s the retraction notice for “Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH,” published in July: Continue reading Author admits to manipulating more than a dozen images in 2013 paper

After 35 years, philosophy journal corrects article…by a cat

A cat philosopher, via Pixabay

In 1982, Bruce Le Catt wrote a response to a paper in the Australasian Journal of Philosophy critiquing an earlier article about prosthetic vision.

But Le Catt was no ordinary author. No, he was a cat, the beloved pet of David Lewis, a world-class philosopher who just happened to be the author of the article about which Bruce Le Catt was commenting.

Lewis’ inside joke wasn’t lost on those who knew him, and the benign deception seems to have been common knowledge in the field since the Le Catt paper appeared in 1982 (which also happens to be the year Cats began its run on Broadway). The paper has been cited four times since it was published, according to Clarivate Analytics. But 25 years later, the journal has finally decided to put an end to the gag.

The joyless notice states plainly: Continue reading After 35 years, philosophy journal corrects article…by a cat

After investigation that started at least 5 years ago, retired ob-gyn prof agrees to 5 years of supervision

Nasser Chegini

A now-retired professor tweaked the findings in seven figures of a 2007 paper, according to a new finding of misconduct released yesterday by the U.S. Office of Research Integrity.

The subject of the findings isn’t a stranger to our readers: We’ve already reported on nine retractions for Nasser Chegini, a former professor of obstetrics and gynecology at the University of Florida (UF) who had won more than $4 million in Federal grants. And Chegini, who retired in early 2012, had been under investigation since at least 2012, with the ORI asking UF to broaden that investigation at one point.

Indeed, the ORI’s notice states that eight of Chegini’s retractions resulted from the UF’s investigation. The ORI’s findings, however, stem from another paper, published in the Journal of Reproductive Immunology, which has not been retracted.

According to the ORI, in that paper, Chegini:

Continue reading After investigation that started at least 5 years ago, retired ob-gyn prof agrees to 5 years of supervision