Authors retract PNAS paper suggesting silk stabilizes vaccines

PNASA PNAS paper that caught the media’s attention for suggesting that adding silk could stabilize vaccines and antibiotics has been pulled after the authors realized there were significant errors in the data analysis. 

According to the notice, the authors agreed to retract the 2012 paper; however, the corresponding author told us the authors did not think a retraction was required as, according to him, the conclusions remained valid.

The paper presented a solution to the long-standing problem that sensitive biological compounds such as vaccines and antibiotics begin to lose their effectiveness outside the recommended temperature range, and naturally biodegrade over time. The degradation process cannot be reversed, and may even speed up during transport or storage under less ideal temperatures.

Here’s the retraction notice: Continue reading Authors retract PNAS paper suggesting silk stabilizes vaccines

Authors pull Nature paper about DEET and flies

Nature CoverAuthors have retracted a Nature paper which identified neurons that render flies sensitive to a potent insect repellent, after losing confidence in the findings. The first author, however, said she does not agree with the retraction, noting that she continues to believe the data are correct.

According to the notice, the remaining authors say they no longer support the claim that certain neurons in the antennae of fruit flies are repelled by DEET, the active ingredient in many insect repellents. The last author told us some of the paper’s results are not in doubt; nevertheless, he added, the paper would not have been published in Nature without the key conclusion, so he and most of his co-authors have pulled the paper in its entirety.

Alongside the retraction, the journal has also published a Brief Communications Arising article by scientists who were unable to reproduce the paper’s findings.

Here’s the retraction notice, published today:
Continue reading Authors pull Nature paper about DEET and flies

JAMA: No plan to pull elephant-cancer risk paper after PETA protest

JAMAJAMA has decided not to retract an article about cancer risk in elephants after receiving a request to do so from an animal rights group.

People for the Ethical Treatment of Animals (PETA) recently protested the 2015 paper, which found that higher levels of a tumor suppressor gene could explain why elephants have a lower risk of cancer. According to PETA, the paper contained inaccurate information that could be used to justify inhumane treatment of elephants. At the time, the journal told us it considers all calls for retraction.

In an email sent to a representative of PETA over the weekend, Howard Bauchner, Editor in Chief at JAMA and The JAMA Network, wrote: Continue reading JAMA: No plan to pull elephant-cancer risk paper after PETA protest

Two journals retracting papers from University of Malaya featuring widely criticized figures

The image that excited twitter: Figure 6 from the Scientific Reports paper
The image that excited Twitter

One journal has retracted a paper containing images that recently raised suspicions of obvious duplications, and another journal is planning to do the same.

Scientists first leveled accusations against the newly retracted paper in Scientific Reports, along with two others by the same researchers, earlier this month on Twitter. One other journal — PeerJ — has announced that it plans to retract one of the questioned papers, as well. The third paper, in Frontiers in Pharmacology, bears an expression of concern.

It was unusually quick action on the part of the journals, as well as the authors’ host institution, the University of Malaya, which announced last week the authors had manipulated figures in all three papers, along with one other.

Here’s today’s retraction notice from Scientific Reports for “Novel piperazine core compound induces death in human liver cancer cells: possible pharmacological properties:”

Continue reading Two journals retracting papers from University of Malaya featuring widely criticized figures

Highly cited cancer researcher logs 8th, 9th retractions

Bharat Aggarwal
Bharat Aggarwal

Bharat Aggarwal, a highly cited cancer researcher who retired last year from MD Anderson, has logged two retractions following an investigation into his work, bringing his total to nine.

Aggarwal has threatened to sue us in the past, and told us that MD Anderson has been investigating his work. Earlier this year, Biochemical Pharmacology retracted seven studies of which he is the only common author, noting the “data integrity has become questionable.” Now, he’s earned two more retractions in Molecular Pharmacology, both for “inappropriate” or “unacceptable” image manipulation.

Both of the notices are paywalled (tsk, tsk). Here’s one for “Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells:” Continue reading Highly cited cancer researcher logs 8th, 9th retractions

Coptic cop-out? Religion journal won’t pull paper based on bogus ‘gospel’

HTR107_02What the Harvard Theological Review giveth, it evidently will not taketh away.

The venerable publication about religious matters is refusing to retract a 2014 article by a noted scholar of early Christianity despite evidence that the article — about Jesus’s wife — was based on a forgery.

The paper, by Harvard theologian Karen King, described a Coptic papyrus called “The Gospel of Jesus’s Wife,” which, among other things, includes language that suggests Christ was married: Continue reading Coptic cop-out? Religion journal won’t pull paper based on bogus ‘gospel’

Journal flags paper over allegations it used competitors’ text, plasmids

MGGA journal has issued an expression of concern (EOC) for a paper on a common crop virus after the authors were accused of using competitors’ unpublished text and plasmids.

Investigations by the journal and the involved institutions — the University of the Witwatersrand in South Africa, where the paper’s authors are based, and North Carolina State University (presumably, where the accusing group is from) — were inconclusive, the notice states.

So the editor flagged “Sequences enhancing cassava mosaic disease symptoms occur in the cassava genome and are associated with South African cassava mosaic virus infection” with an EOC:

Continue reading Journal flags paper over allegations it used competitors’ text, plasmids

Retract – and replace? JAMA may expand use of this tool

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Annette Flanagin

Remember last week, when JAMA replaced an article about the impact of moving homes on kids’ mental health after discovering some errors in the analysis? We’re going to see more of these somewhat unusual notices coming out of JAMA journals in the near future – the JAMA Network journals may   issue more “retract and replace” decisions for papers, in which it pulls an old version of an article and replaces it with a corrected one. But it’s not a correction — we spoke with Annette Flanagin, the Executive Managing Editor for The JAMA Network, to learn more. 

Retraction Watch: We’ve spotted three “retract and replace” notices in JAMA journals, including one issued earlier this year for a highly cited paper that contained “pervasive errors,” and the one last week about the impact of moving on kids’ mental health. How do you decide whether a paper will be retracted and replaced, or just retracted? Continue reading Retract – and replace? JAMA may expand use of this tool

Dental paper pulled for “wrong content with serious consequences”

Clinical Oral InvestigationsAn article on how missing teeth affect chewing was — well, pulled — when someone noticed a few errors. The journal later published a corrected version.

The retraction for “Chewing ability in an adult Chinese population” appeared in Clinical Oral Investigations in 2012, but we’re sharing it with you now because the notice contains some remarkable language:

This article has been withdrawn due to wrong content with serious consequences such as danger to people’s health.

Last author Nico H.J. Creugers, who works at Radboud University Medical Center in the Netherlands, told us: 

Continue reading Dental paper pulled for “wrong content with serious consequences”

Seventh retraction appears for cancer researcher who sued PubPeer commenters

sarkar
Fazlul Sarkar

Fazlul Sarkar, who sued PubPeer commenters for criticizing his work, has logged two more retractions, bringing his total to seven.

The two retractions appear in the Journal of Cellular Physiology, and follow five others released last week by another Wiley journal, Journal of Cellular Biochemistry. All notices mention an investigation at Wayne State University, where Sarkar is on the faculty.

Here’s the notice for “Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype:” Continue reading Seventh retraction appears for cancer researcher who sued PubPeer commenters