Retractions aren’t enough: Why science has bigger problems

Andrew Gelman
Andrew Gelman

Scientific fraud isn’t what keeps Andrew Gelman, a professor of statistics at Columbia University in New York, up at night. Rather, it’s the sheer number of unreliable studies — uncorrected, unretracted — that have littered the literature. He tells us more, below.

Whatever the vast majority of retractions are, they’re a tiny fraction of the number of papers that are just wrong — by which I mean they present no good empirical evidence for their claims.

I’ve personally had to correct two of my published articles.   Continue reading Retractions aren’t enough: Why science has bigger problems

Journal pulls parasite paper over potential for patient harm

Parasitology ResearchA journal has retracted a paper about a molecular diagnosis for leishmaniasis out of concern it could lead to incorrect clinical diagnoses. 

According to Parasitology Research, all data behind the figures in the main manuscript and supporting information are correct, but the authors’ misinterpretation of the data could lead doctors to diagnose patients incorrectly. 

Let’s take a look at the retraction notice, which tells us a bit more about the nature of the problem: Continue reading Journal pulls parasite paper over potential for patient harm

Duke researcher adds another retraction in JCI, bringing count to 15

JCIWe’ve found another retraction for Erin Potts-Kant, a former researcher at Duke, bringing her total to 15.

Yesterday we reported on two new retractions for Potts-Kant in PLoS ONE, which earned her a spot in the top 30 on our leaderboard. As with the others, the latest paper, in the Journal of Clinical Investigation, is marred by “unreliable” data.

Here’s the retraction notice for “In utero supplementation with methyl donors enhances allergic airway disease in mice“:

Continue reading Duke researcher adds another retraction in JCI, bringing count to 15

Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

PLOS OneA pair of Duke researchers who each have more than 10 retractions have earned some more.

Both of the newly retracted papers — originally published in 2012 by PLOS ONE — list Erin Potts-Kant as a co-author; one includes her former supervisor, Michael Foster, as lead author. The pair has since left Duke (Potts-Kant was arrested for using school credit cards to shop at the likes of Target, and Foster retired). The reason provided for these retractions will be familiar to anyone who’s been following their case — there were “concerns about the reliability” of the data.

By our count, Potts-Kant now has 14 retractions, making her one of the few women to hold a position on our leaderboard.

Here’s the retraction notice for “Iron Supplementation Decreases Severity of Allergic Inflammation in Murine Lung,” a paper that lists both Foster and Potts-Kant as authors:

Continue reading Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

Physics journal pulls two papers for data shortcuts

New Journal of PhysicsA publisher is retracting two papers today by a team of physicists who took a short cut in reporting their data.

The papers present a method for imaging very small things — like biological processes on a molecular scale — that could be an alternative to electron microscopy, as the authors explain in a video. But after the papers were published in the New Journal of Physics, last author Ulf Leonhardt, now based at the Weizmann Institute of Science, found out that some of the data

 were pixel-by-pixel mirror-symmetric, which is impossible for genuine experimental data.

One of the researchers co-authored a subsequent paper that acknowledges one of the papers incorrectly assumed the data were symmetrical, and could therefore be extrapolated from one side to the other. A representative of the publisher told us they have not seen any signs of misconduct, and the problem seemed to result from a “series of apparent miscommunications between the authors.”

Here’s the retraction notice for “Evidence for subwavelength imaging with positive refraction:” Continue reading Physics journal pulls two papers for data shortcuts

Economics paper retracted due to “extensive changes”

727710An article has been retracted from a proceedings of an economics conference after the publisher identified errors in several parts of the study.

The retraction follows criticism from a Romanian blogger, who contacted the journal about several issues, and posted communications she received about the paper, “Sustainability of Social Enterprises: A Discourse Analysis.” It was part of a volume of Procedia Economics and Finance from a 2014 conference, “Economic Scientific Research – Theoretical, Empirical and Practical Approaches,” also known as ESPERA 2014.

According to the paper, peer review was

under responsibility of the Scientific Committee of ESPERA 2014.

Apparently, the peer review process missed a few errors. The retraction note explains:

Continue reading Economics paper retracted due to “extensive changes”

NEJM quickly corrects disclosure statement, errors in diabetes paper

NEJM LogoAfter publishing a paper about neuropathy in diabetic patients last week, The New England Journal of Medicine (NEJM) immediately corrected it after editors learned of errors and some missing disclosures within the article.

The notice explains that the sole author of the paper, “Diabetic Sensory and Motor Neuropathy,” reported incorrect doses for several medications, and received royalties for the tool to measure quality of life used in the paper. The author told us all the declarations were “discussed in detail” between him and the journal, and both parties agreed to the final decision. 

Let’s take a look at the lengthy correction notice — what some of our readers might call a “mega-correction:” Continue reading NEJM quickly corrects disclosure statement, errors in diabetes paper

Two more retractions bring total to 9 for neuroscience duo

Journal of Neuroscience CoverAfter the first author admitted to fraud, his colleagues have retracted a 2013 paper in the Journal of Neuroscience, as well as a 2015 book chapter about working memory.

The retractions come as part of a backstory of pulled papers authored by psychologist Edward Awh and his former graduate student David Anderson when he was based at the University of Oregon in Eugene. The pair retracted four papers last year after Anderson admitted to misconduct during an investigation by the U.S. Office of Research Integrity (and spoke to us about it last July). This led Awh — now based at the University of Chicago in Illinois — to take a second look at the other publications he’d co-authored with Anderson; earlier this year, Awh retracted two others, and informed us more would be coming, including the two most recent publications

First, let’s take a look at the retraction note for the Journal of Neuroscience paper, about remembered items and task performance: Continue reading Two more retractions bring total to 9 for neuroscience duo

How did two papers on same gene with different authors, publishers, end up with identical retraction notices?

1-s2.0-S0006291X16X00058-cov150h1Here’s an interesting case: We’ve found two retracted papers that describe the same gene, and both have nearly identical retraction notices. What’s unusual is that the two papers don’t have any authors in common, and appeared in two different journals published by two different companies.

The cause of both papers’ demise: Plagiarism, and use of unpublished data without permission “from an unnamed source,” who wishes to remain that way. The author of one of the papers confirmed to us that the unnamed source is a “3rd party service company.” Springer told us that the third party in the other paper, however, is another researcher.

It’s a puzzling case, to be sure. We think we have uncovered some of what happened, but remain slightly fuzzy on the details.

Here’s the first retraction, for “KDM3A interacted with p53K372me1 and regulated p53 binding to PUMA in gastric cancer,” originally published online September 30 by Biochemical and Biophysical Research Communications:

Continue reading How did two papers on same gene with different authors, publishers, end up with identical retraction notices?

Paper on GI cancers linked to AIDS pulled for errors that upped tumor incidence

gastroGastroenterology has retracted a 2012 article on GI cancers associated with AIDS after the authors, from the National Cancer Institute, acknowledged that a “programming” error led them to overestimate the incidence of the tumors.

The paper, “Increased Risk of Stomach and Esophageal Malignancies in People With AIDS,” received a significant amount of attention when it first appeared, including a press release from the American Gastroenterological Association and several news articles. Here are its primary findings, according to the abstractContinue reading Paper on GI cancers linked to AIDS pulled for errors that upped tumor incidence