Category: data issues

JAMA authors retract (and replace) paper about moves and kids’ mental health

JAMAJAMA authors have retracted — and replaced — a 2014 paper about the mental health effects of household moves on kids, after they found errors while completing an additional analysis.

The original paper concluded that in “families who moved out of high-poverty neighborhoods, boys experienced an increase and girls a decrease in rates of depression and conduct disorder,” according to a press release issued by the journal along with the paper (which also got some press attention from Reuters). But part of that conclusion is wrong.

The authors write in a notice for “Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence” that:

Continue reading JAMA authors retract (and replace) paper about moves and kids’ mental health

Pharmacology journal pulls paper for “insufficient scientific quality;” authors disagree

Frontiers in PharmacologyAgainst the authors’ wishes, a pharmacology journal has retracted a paper after receiving two messages questioning the “soundness of the experimental results.”

The editors of the journal, Frontiers in Pharmacology, issued an expression of concern about the paper in April 2016, and investigated it following the allegations. According to the retraction notice, the authors disagree with the retraction.

Here’s the retraction notice for the paper: Continue reading Pharmacology journal pulls paper for “insufficient scientific quality;” authors disagree

Conservative political beliefs not linked to psychotic traits, as study claimed

American Journal of Political Science

Researchers have fixed a number of papers after mistakenly reporting that people who hold conservative political beliefs are more likely to exhibit traits associated with psychoticism, such as authoritarianism and tough-mindedness.

As one of the notices specifies, now it appears that liberal political beliefs are linked with psychoticism. That paper also swapped ideologies when reporting on people higher in neuroticism and social desirability (falsely claiming that you have socially desirable qualities); the original paper said those traits are linked with liberal beliefs, but they are more common among people with conservative values.

We’re not clear how much the corrections should inform our thinking about politics and personality traits, however, because it’s not clear from the paper how strongly those two are linked. The authors claim that the strength of the links are not important, as they do not affect the main conclusions of the papers — although some personality traits appear to correlate with political beliefs, one doesn’t cause the other, nor vice versa.

In total, three papers have been corrected by authors, and a correction has been submitted on one more.

We’ll start with an erratum that explains the backstory of the error in detail. It appears on “Correlation not Causation: The Relationship between Personality Traits and Political Ideologies,” published by the American Journal of Political Science: Continue reading Conservative political beliefs not linked to psychotic traits, as study claimed

JAMA journals pull 3 papers by same authors for misconduct

JAMAJAMA and another journal in its network have retracted three 2005 papers about preventing hip fractures, after an admission of scientific misconduct. 

All papers are being retracted over concerns about data integrity, and “inappropriate assignment of authorship.” Four of the authors — all based in Japan — have co-authored all of the three newly retracted papers, and also share authorship of a previous retraction from 2015. 

The JAMA paper was tagged with an Expression of Concern last year, regarding the “conduct, integrity, and scientific validity” of the paper. 

Here’s the retraction notice for the JAMA paper, “Effect of Folate and Mecobalamin on Hip Fractures in Patients With Stroke:” Continue reading JAMA journals pull 3 papers by same authors for misconduct

Author “committed serious mistakes,” finds Taipei investigation

Arteriosclerosis Thrombosis and Vascular BiologyAn investigation at Taipei Medical University found that an author made “serious mistakes” when preparing a manuscript.

The journal prompted the university to investigate the paper, which looks at the role of a protein in repairing arteries after an injury.

The retraction notice explains:

Continue reading Author “committed serious mistakes,” finds Taipei investigation

Epilepsy researcher gets retraction, correction after former colleague flags work

EpilipsiaEpilepsy researcher Toni Schneider has received a retraction and a correction in quick succession, after a former colleague raised red flags about the work. 

The retraction for Schneider, based at the University of Köln in Germany, is for “unintentional inclusion of erroneous data” due to limitations of the recording system used in the paper, according to the notice. 

Marco Weiergräber, a former colleague of Schneider’s, has claimed that the authors of the paper did not use the test properly. The journal editor, however, told us he believes the original analysis is an “honest mistake,” and there is “no evidence” to suggest that the authors intentionally published incorrect analyses.

Here’s the retraction notice, issued by the journal in March 2016: Continue reading Epilepsy researcher gets retraction, correction after former colleague flags work

Neuro journal pulls article for data theft, prompts misconduct probe

annneuro

Neuroscientists have retracted a research letter less than two months after it appeared, admitting they appeared to pass off others’ data as their own.

Two of the researchers are listed as affiliated with the University of California, San Francisco (UCSF), and the incident has led to a misconduct investigation at the institution, a UCSF spokesperson told us.

The article, “DNAJC6 variants in Parkinson’s disease and amyotrophic lateral sclerosis,” appeared in April. It was quickly followed by this notice, dated in May: Continue reading Neuro journal pulls article for data theft, prompts misconduct probe

Cancer researchers: We took data from another lab

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Authors have admitted to using material from another lab for their paper on neuroblastoma.

A spokesperson for Springer told us that the theft came to light when:

The scientists, from whom the data originated, contacted the journal.

The editor in chief of the journal investigated the case, the spokesperson told us, and then issued this retraction notice:

Continue reading Cancer researchers: We took data from another lab

How should journals update papers when new findings come out?

NEJM Logo

When authors get new data that revise a previous report, what should they do?

In the case of a 2015 lung cancer drug study in the New England Journal of Medicine (NEJM), the journal published a letter to the editor with the updated findings.

Shortly after the paper was published, a pharmaceutical company released new data showing the drug wasn’t quite as effective as it had seemed. Once the authors included the new data in their analysis, they adjusted their original response rate of 59%  — hailed as one of a few “encouraging results” in an NEJM editorial at the time of publication — to 45%, as they write in the letter. One of the authors told us they published the 2015 paper using less “mature” data because the drug’s benefits appeared so promising, raising questions about when to publish “exciting but still evolving data.”

It’s not a correction, as the original paper has not been changed; it doesn’t even contain a flag that it’s been updated. But among the online letters about the paper is one from the authors, “Update to Rociletinib Data with the RECIST Confirmed Response Rate,” which provides the new data and backstory:

Continue reading How should journals update papers when new findings come out?

Structural biology corrections highlight best of the scientific process

Nature_latest-coverIf you need evidence of the value of transparency in science, check out a pair of recent corrections in the structural biology literature.

This past August, researchers led by Qiu-Xing Jiang at the University of Texas Southwestern Medical Center corrected their study, first published in February 2014 in eLife, of prion-like protein aggregates called MAVS filaments, to which they had ascribed the incorrect “helical symmetry.” In March, Richard Blumberg of Harvard Medical School, and colleagues corrected their 2014 Nature study of a protein complex called CEACAM1/TIM-3, whose structure they had attempted to solve using x-ray crystallography.

In both cases, external researchers were able to download and reanalyze the authors’ own data from public data repositories, making it quickly apparent what had gone wrong and how it needed to be fixed — highlighting the very best of a scientific process that is supposed to be self-correcting and collaborative. Continue reading Structural biology corrections highlight best of the scientific process