January 2016 – Page 7 – Retraction Watch

Cancer study pulled when published without supervisor’s consent

The Turkish Journal of Medical Sciences has retracted a paper after concerns surfaced from a researcher who claims to have supervised the research but was not listed as a co-author.

The first author completed the research — which explored the use of epigenetic alterations as potential early signs of cancer — as part of her master’s degree, under the supervision of Muy-Teck Teh at the Barts & The London School of Medicine & Dentistry. When Teh contacted the journal to say he had not consented to the publication, Ayesha Umair claimed she had paid for the research herself.

Here’s the retraction note for “Quantitative study of epigenetic signature in head and neck squamous cell carcinoma,” which tells us more about the dispute: Continue reading Cancer study pulled when published without supervisor’s consent

Nature retracts paper six years after it was flagged for fraud

Nature retracted a paper on protein structures today, six years after an investigation at the University of Alabama identified several structures that were “more likely than not falsified and/or fabricated” by one of the authors.

The paper came under scrutiny soon after it was published in 2006. A letter published in Nature that same year pointed out “physically implausible features in the structures it described.” That triggered the investigation at the University of Alabama, the result of which was published in 2009, identifying “nine publications related to the same protein structures that should be retracted from various scientific journals.” Everything was pinned on last author H.M. Krishna Murthy, who the investigation determined was “solely responsible for the fraudulent data.”

A 2009 Nature news article on the investigation declared that the “fraud is the largest ever in protein crystallography.”

We’re not sure what took Nature so long to retract the letter, titled “The structure of complement C3b provides insights into complement activation and regulation.” Here’s the note, which explains that not all the authors agreed to the retraction:

Continue reading Nature retracts paper six years after it was flagged for fraud

Why retraction shouldn’t always be the end of the story

When researchers raised concerns about a 2009 Science paper regarding a new way to screen for enzymatic activity, the lead author’s institution launched an investigation. The paper was ultimately retracted in 2010, citing “errors and omissions.”

It would seem from this example that the publishing process worked, and science’s ability to self-correct cleaned up the record. But not so to researchers Ferric Fang and Arturo Casadevall.

Fang, of the University of Washington, Seattle, and Casadevall, of Johns Hopkins — who have made names for themselves by studying retractions — note today in an article for Chemistry World that

Continue reading Why retraction shouldn’t always be the end of the story

Third retraction appears for Leiden researcher fired in 2013

A researcher who was fired from Leiden University Medical Center in 2013 for fraud has notched a third retraction, following an investigation by her former workplace.

When Leiden fired Annemie Schuerwegh, they announced two retractions of papers that contained manipulated data. This third retraction — the last, according to a spokesperson for the center — is for “a discrepancy between the data reported in the article and the original collected data,” per the note.

The 2011 paper, “Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium” published in Arthritis Research & Therapy, suggests the source of a protein involved in rheumatoid arthritis. It has been cited 51 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note:

Continue reading Third retraction appears for Leiden researcher fired in 2013

Voinnet’s notice count grows, as he notches his 18th correction

Olivier Voinnet, a high-profile plant scientist at ETH Zurich, has earned a mega-correction. It wrapped up a rough year for the biologist, which included his seventh retraction, and a CNRS investigation that found evidence of misconduct.

This latest correction, to a paper on the mechanisms behind RNA silencing in Arabidopsis, was published in RNA. The 2007 paper has been cited 101 times, according to Thomson Scientific’s Web of Knowledge. The corrigendum modifies three figures in total.

The notice is long, so we’re not going to post the whole thing here. The first error in “Transitivity in Arabidopsis can be primed, requires the redundant action of the antiviral Dicer-like 4 and Dicer-like 2, and is compromised by viral-encoded suppressor proteins” is a clarification to a legend:

Continue reading Voinnet’s notice count grows, as he notches his 18th correction