A new letter signed by 20 researchers is casting additional doubts on the validity of a potentially invaluable lab tool — and alleges the lab that produced the initial results turned them away when they tried to replicate its findings in mammalian cells.
In a letter published this week in Protein & Cell, the researchers add their voices to the critics of the gene-editing technique, first described earlier this year in Nature Biotechnology.
The researchers outline their attempts to apply the technique — known as NgAgo — to a variety of cell types, which fell short:
Continue reading More questions arise over gene-editing tool