Category: nature cell biology

Nature Cell Biology retracts hotly debated cancer paper

ncbLast week, we learned a 2016 paper heavily discussed on PubPeer might be retracted — today, we learned that Nature Cell Biology has indeed pulled the paper, citing inappropriate image modifications.

As we reported last week, a comment on PubPeer flagged as coming from an author said they had requested a retraction. A representative of National Taiwan University (NTU) told us the first author had resigned, and the paper was under investigation — an investigation which included the last author, a prominent researcher who is also a vice president at another institution in Taiwan.

Here’s Nature Cell Biology‘s official statement about the paper, in the form of a retraction notice that appears to be written by the authors:  Continue reading Nature Cell Biology retracts hotly debated cancer paper

More questions arise over gene-editing tool

13238A new letter signed by 20 researchers is casting additional doubts on the validity of a potentially invaluable lab tool — and alleges the lab that produced the initial results turned them away when they tried to replicate its findings in mammalian cells.

In a letter published this week in Protein & Cell, the researchers add their voices to the critics of the gene-editing technique, first described earlier this year in Nature Biotechnology.

The researchers outline their attempts to apply the technique — known as NgAgo — to a variety of cell types, which fell short:

Continue reading More questions arise over gene-editing tool

Nature Cell Bio paper may be headed for retraction

ncbA Nature Cell Biology paper published only a few months ago by prominent researchers in Taiwan has sparked a heated discussion on PubPeer, which now includes a comment allegedly from an author saying they have requested its retraction.

Although a representative of the journal wouldn’t confirm to us that the authors had requested a retraction, the comment on PubPeer says the paper contains several figures that were “inappropriately manipulated” by the first author.

Here’s the full comment on PubPeer, tagged as coming from one of the authors of the paper:

Continue reading Nature Cell Bio paper may be headed for retraction

Nature Cell Biology insulin paper retracted over antibody problems

nature cell biologyA Nature Cell Biology article on insulin regulation has been retracted after scientists noted that the antibodies used in their research were not as specific as they had previously believed.

The notice is clear on the problems with the science, which together “call into question the main conclusions of the paper.” Three of the paper’s five authors were employed at Novartis at the time of publication.

Here’s the notice for “Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion”: Continue reading Nature Cell Biology insulin paper retracted over antibody problems

Updated: Former Vanderbilt scientist faked nearly 70 images, will retract 6 papers: ORI

ori logoA former Vanderbilt University biomedical engineer committed fraud on a massive scale, according to a new Office of Research Integrity (ORI) report.

Igor Dzhura is banned from receiving federal funding for three years, and is retracting six papers, which have been cited more than 500 times. Since leaving Vanderbilt, he has worked at SUNY Upstate Medical University, and now works at Novartis.

According to the ORI, Dzhura was a busy boy at Vanderbilt, faking images and drastically inflating the number of experiments he conducted by duplicating computer files and saving them in nested folders. The total body count from his work includes: Continue reading Updated: Former Vanderbilt scientist faked nearly 70 images, will retract 6 papers: ORI

Shigeaki Kato up to 28 retractions, with three papers cited nearly 700 times

Shigeaki Kato
Shigeaki Kato

Former University of Tokyo researcher Shigeaki Kato has notched his 26th, 27th, and 28th retractions, all in Nature Cell Biology. The three papers have been cited a total of 677 times.

Here’s the notice for “DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs:” Continue reading Shigeaki Kato up to 28 retractions, with three papers cited nearly 700 times