Category: clinical study retractions

BioMed Central retracting 43 papers for fake peer review

bmc logoBioMed Central is retracting 43 papers, following their investigation into 50 papers that raised suspicions of fake peer review, possibly involving third-party companies selling the service.

In November 2014 we wrote about fake peer reviews for Nature; at that point there had been about 110 retractions across several journals. The addition of 16 retractions by Elsevier for the same reason, and today’s 43 from BMC, brings retractions resulting from the phenomenon up to about 170.

BMC has also contacted institutions regarding 60 additional papers that were rejected for publication, but seem to be part of the same kind of scam. Regarding the third-party agents, BMC senior editor of scientific integrity Elizabeth Moylan writes: Continue reading BioMed Central retracting 43 papers for fake peer review

Pain paper scratched for authorship issues

ejacoverA group of pain researchers in Austria has lost their 2014 paper in the European Journal of Anaesthesiology because one of the authors wasn’t, well, one of the authors.

The article, “Intravenous nonopioid analgesic drugs in chronic low back pain patients on chronic opioid treatment: A crossover, randomised, double-blinded, placebo-controlled study,” came from a team at the Medical University Vienna and Evangelical Hospital Vienna.

During the study, the authors tested whether intravenous infusions of nonopioid drugs (such as paracetamol, or Tylenol) helped people with chronic back pain who take opioids regularly. They found that people’s pain levels decreased in the days leading up to treatment, when they were receiving a placebo, but not after the actual infusion. The results likely stem from “expectation-related mechanisms,” they wrote. Continue reading Pain paper scratched for authorship issues

Two more retractions appear for prominent MIT cancer researcher Robert Weinberg

genes and developmentTwo identical retraction notices have popped up for MIT professor Robert Weinberg, a highly-cited cancer researcher who had a retraction and a correction in 2013, both in Cancer Cell. 

These two new retractions, in Genes and Development, stem directly from another paper by Weinberg and colleagues in Cell that will apparently be retracted, as the “same analytical methodology was used,” according to the notices [see bottom of the post for an update].

Weinberg is highly regarded, and at least 20 of his papers have been cited over a thousand times.

First author Scott Valastyan was a promising postdoc at the time of the paper’s publication. He was a 2011 Runyon Fellow at Harvard, a three-year, $156,000 award for outstanding cancer postdocs. He doesn’t seem to have published anything since 2012, though he is listed as a joint inventor with Weinberg on patents filed in 2009 and 2014.

Here are the notices for “Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis” (cited 73 times, according to Thomson Scientific’s Web of Knowledge) and “Activation of miR-31 function in already-established metastases elicits metastatic regression” (cited 54 times), both paywalled: Continue reading Two more retractions appear for prominent MIT cancer researcher Robert Weinberg

Sticky situation: Paper using honey for healing pulled over data issues

honey
Image via Hillary Stein

A paper on dressing wounds with honey has been retracted after the journal realized that an outlier patient was throwing off the data analysis.

Honey has been used for millennia as an antimicrobial wound dressing. Doctors can even buy sterile preparations of the sweetener. But the evidence that honey is better than other wound dressings is still inconclusive.

According to the retracted paper, published in International Wound Journal in 2008, Manuka honey has an acidic pH which helps reduce the alkaline environment of chronic woulds. Indeed, the authors found that Manuka honey dressings lowered wound pH and reduced wound size.

Sadly, the paper was pulled in 2014, after someone realized one patient had a particularly large wound that was throwing off statistics. The injury was 61 cm^2 at the beginning of the study, while the others ranged from .9 to 22 cm^2. After removing that patient from the analysis, the results no longer held up.

Continue reading Sticky situation: Paper using honey for healing pulled over data issues

Psychology retractions have quadrupled since 1989: study

stapel
Diederik Stapel

Marc Hauser. Dirk Smeesters. Diederik Stapel.

Psychology has been home to some of the most infamous cases of fraud in recent years, and while it’s just a few bad apples who are spoiling the bunch, the field itself has seen an overall increase in retractions, according to a new paper by Jürgen Margraf appearing in Psychologische Rundschau and titled “Zur Lage der Psychologie.”

That increase, Margraf found, is not entirely due to its most well-known fraudsters. Here’s the relevant figure:

Continue reading Psychology retractions have quadrupled since 1989: study

Diabetes researcher won’t give up court fight to quash expressions of concern

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

Apparently, you can’t keep Mario Saad down.

The researcher, who had 12 figures in a paper corrected this week, was dealt a setback last week when a judge denied his motion to remove expressions of concern on four of his papers in the journal Diabetes, saying that would have amounted to prior restraint — essentially, censorship (a no-no, thanks to the First Amendment).

Saad and his attorneys, however, were undeterred. They filed a motion for reconsideration just four days later, along with a brief, arguing: Continue reading Diabetes researcher won’t give up court fight to quash expressions of concern

Second exercise study retracted in four-paper pileup

nursing and health scienceWe recently wrote about three papers on heart health and exercise that came under fire for reporting the same trial in three different ways. Actually, make that four ways (so far).

The Wiley journal Nursing and Health Sciences has retracted a fourth paper from the group, saying the “main study” was “previously published.” The notice mentions all three previous papers, one of which has already been retracted and another withdrawn from publication.

Here’s the notice for “Can the transtheoretical model motivate patients with coronary heart disease to exercise?”: Continue reading Second exercise study retracted in four-paper pileup

Heart journal issues expression of concern after fraud report

circulationThe American Heart Association’s journal Circulation has issued an expression of concern for a paper about the molecular underpinnings of arrhythmias that was co-authored by a biomedical engineer who committed fraud on a massive scale.

According to an investigation by the Office of Research Integrity (ORI), former Vanderbilt engineer Igor Dzhura faked nearly 70 images and drastically over-estimated the number of experiments he conducted. He was banned from receiving federal funding for three years.

The fraud has resulted in six retracted papers, Dzhura has agreed to retract six papers, which have been cited more than 500 times. [Ed. note: at this time, only one paper has actually been retracted]

Continue reading Heart journal issues expression of concern after fraud report

Judge denies motion by researcher to quash Diabetes expressions of concern

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

American Diabetes Association 1, Mario Saad 0.

As reported by the National Law Journal, a federal judge in Boston has denied Saad’s requests to stop the ADA’s flagship journal, Diabetes, from publishing expressions of concern about four of Saad’s papers, and to prevent the journal from retracting the studies.

Saad filed suit against the ADA on February 5. Judge Timothy Hillman wrote in his order yesterday that approving the researcher’s motion would have violated the right to free speech: Continue reading Judge denies motion by researcher to quash Diabetes expressions of concern

Frontiers lets HIV denial article stand, reclassifies it as “opinion”

frontiers phFollowing an investigation sparked by criticism for its decision to publish a paper questioning the link between HIV and AIDS, a Frontiers journal has decided to not retract the article but rebrand it as an “opinion.”

In September, 2014, Patricia Goodson, a professor of health education at Texas A&M University, published an article called “Questioning the HIV-AIDS hypothesis: 30 years of dissent.”

The paper was quickly called into question, and the journal, Frontiers in Public Health, issued a statement of concern and promised to look into the problem. Now, they’ve announced their solution: call the paper an “opinion” and publish an argument against it.

Continue reading Frontiers lets HIV denial article stand, reclassifies it as “opinion”