Category: clinical study retractions

Paper linking fecal transplants to obesity in rats retracted for faked data

Diabetes Cover

A paper linking the fecal microbiome to obesity has been retracted after it became clear that one of the co-authors faked some of the data.

The 2014 paper in Diabetes — which found that rats given fecal transplants from obese mice were more likely to become obese themselves if given a particular diet — was pulled after after an institutional investigation found a co-author guilty of falsifying data underlying one figure and fabricating the data of two others.

Co-author Yassine Sakar — formerly based at the French National Institute of Agronomic Research (INRA) in Paris, France — was found responsible for the misconduct. But an official from the institution said that some responsibility must also be shared by the corresponding author Mihai Covosa, who has since resigned from the institution.

Here’s the retraction notice: Continue reading Paper linking fecal transplants to obesity in rats retracted for faked data

Research assistant fired for using student’s thesis in a paper

Reviews in Medical Microbiology

A research assistant at King Saud University (KSU) has lost his job after he used material from a student’s thesis without permission or attribution in a paper.

Lakshmana Krishnappa was terminated after a disciplinary committee considered his case last November, the vice dean for postgraduate training and research at KSU told Retraction Watch. In April of last year, Krishnappa retracted a paper published in January 2015 — we think that’s the date; the journal doesn’t make it all that clear — that included plagiarized material, published in Reviews in Medical Microbiology. He recently lost a second unrelated paper for duplication.

Here’s the retraction notice for the Reviews in Medical Microbiology paper, “Acinetobacter baumannii: pathogenecity, virulence factors and their correlation with adherence and invasion:”

Continue reading Research assistant fired for using student’s thesis in a paper

Biologist critiques own paper, journal retracts it — against her wishes

Evolution Cover ImageThe journal Evolution has retracted a 2007 paper about the roles of the different sexes in searching for mates, after the same author critiqued the work in a later paper. 

The case raises important questions about when retractions are appropriate, and whether they can have a chilling effect on scientific discourse. Although Hanna Kokko of the University of Zurich, Switzerland — who co-authored both papers — agreed that the academic literature needed to be corrected, she didn’t want to retract the earlier paper; the journal imposed that course of action, said Kokko. 

Let’s take a look at the retraction note: Continue reading Biologist critiques own paper, journal retracts it — against her wishes

The standard in transparency? Editor praises author honesty that led to retraction in anesthesia journal

a&Amay16

Sometimes, a junior member of the team sees things an editor-in-chief misses.

Regular readers know that we’re always delighted when we get a chance to commend researchers and journals for doing the right thing. Here’s an example that sets the standard.

Anesthesia & Analgesia (A&A) is retracting a 2015 paper which purportedly found important differences in patient outcomes based on the quality of their anesthesiologists. The trouble with the article: Continue reading The standard in transparency? Editor praises author honesty that led to retraction in anesthesia journal

Author dispute retracts paper suggesting NSAIDs curb growth in rats

jpedorthoThe corresponding author asked the Journal of Pediatric Orthopaedics to retract an article that found popular pain medicines can curb growth in rats, in light of an unresolved authorship dispute.

The article, “Nonsteroidal Anti-Inflammatory Drugs Cause Inhibition of the Growth Plate in Cultured Rat Metatarsal Bones,” details preliminary results that indicate nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce growth in rat bones in a dose-dependent manner, suggesting caution in treating chronic inflammatory diseases in children. The editor told us the paper was “highly rated” by reviewers and the results were “never in question,” but the senior author asked to pull the paper after failing to resolve a dispute with a researcher who asked to be added as an author.

According to the notice:  Continue reading Author dispute retracts paper suggesting NSAIDs curb growth in rats

Raw files help fix 2003 figure by heart researcher accused of fraud

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A researcher accused of misconduct by an anonymous Japanese blogger has corrected a 2003 paper in Circulation Research, after providing a university investigation with the original source files.

Allegations of fraud have dogged Shokei Kim-Mitsuyama for years, and even caused him to step down from his position as editor in chief at another journal. However, Kim-Mitsuyama and his colleagues call the latest correction a “mistake,” which didn’t affect any of the paper’s conclusions.

We’ve unearthed a total of five publications co-authored by Kim-Mitsuyama that have earned corrections, the latest of which cites an investigation by the university:

Continue reading Raw files help fix 2003 figure by heart researcher accused of fraud

Authors retract, replace highly cited JAMA Psych paper for “pervasive errors”

JAMA PsychiatryAuthors have retracted a highly cited JAMA Psychiatry study about depression after failing to account for some patient recoveries, among other mistakes.

It’s a somewhat unusual notice — it explains that the paper has been retracted and replaced with a new, corrected version.

The study, which included 452 adults with major depressive disorder, concluded that cognitive therapy plus medication works better to treat depression than pills alone. But after it was published, a reader pointed out that some of the numbers in a table were incorrect. The authors reviewed the data and redid their analysis, and discovered “a number of pervasive errors.”

The notice (termed “notice of retraction and replacement”) explains the consequences of those errors:

Continue reading Authors retract, replace highly cited JAMA Psych paper for “pervasive errors”

Journals retract two heart papers with “nearly identical” abstracts

Screen Shot 2016-02-22 at 4.46.17 PMJournals have retracted two papers after realizing that they contain “nearly identical” abstracts and introductions, published only months apart. 

The two retracted papers, along with a third that also contains similar text, all conclude that a certain polymorphism could signal a risk for coronary artery disease among Chinese people, though each paper presents different data. The papers do not have any authors in common; the first authors are all based at different hospitals in China. The editor in chief of one journal told us that some of the reviewers did not use institutional email addresses, which leaves open the possibility that they were fake emails, and the peer-review process was compromised.

Here’s the first retraction notice, for “Fibroblast growth factor receptor 4 polymorphisms and susceptibility to coronary artery disease,” published in DNA and Cell Biology. The notice states the paper contains:

Continue reading Journals retract two heart papers with “nearly identical” abstracts

NEJM quickly corrects disclosure statement, errors in diabetes paper

NEJM LogoAfter publishing a paper about neuropathy in diabetic patients last week, The New England Journal of Medicine (NEJM) immediately corrected it after editors learned of errors and some missing disclosures within the article.

The notice explains that the sole author of the paper, “Diabetic Sensory and Motor Neuropathy,” reported incorrect doses for several medications, and received royalties for the tool to measure quality of life used in the paper. The author told us all the declarations were “discussed in detail” between him and the journal, and both parties agreed to the final decision. 

Let’s take a look at the lengthy correction notice — what some of our readers might call a “mega-correction:” Continue reading NEJM quickly corrects disclosure statement, errors in diabetes paper

Three HER2-cancer review papers tagged with expressions of concern

The Oncologist Her 2 expression of concern

The Oncologist has tagged three review papers that share a first author with an expression of concern. The three papers, which have together been cited more than 1,000 times, focus on HER2, a gene that can contribute to breast cancer.

Though the papers contain errors, the conclusions — about how the HER2 gene serves as a predictive factor for breast cancer, and a target for therapies — remain unchanged, according to the EOC. The editor of the journal notes that the conclusions of the papers have been confirmed by other publications. Two of the papers are more than 10 years old, and today many patients continue to be treated with medications that target HER2, such as Herceptin.

Here’s the expression of concern:

Continue reading Three HER2-cancer review papers tagged with expressions of concern