Anversa cardiac stem cell lab earns 13 retractions

Piero Anversa

Two months after Harvard and the Brigham and Women’s Hospital said they were requesting the retraction of more than 30 papers from a former cardiac stem cell lab there, two American Heart Association journals have retracted more than a dozen papers from the lab.

Yesterday, Circulation retracted three papers, and Circulation Research retracted 10. All 13 were among 15 subjected to expressions of concern last month. Continue reading Anversa cardiac stem cell lab earns 13 retractions

Journals stamp expressions of concern on 15 papers from Anversa’s cardiac stem cell lab

Piero Anversa

More than four and a half years after questions were first raised about work in a cardiac stem cell lab at Harvard and the Brigham and Women’s Hospital, a year and a half after the Brigham and Partners Healthcare paid $10 million to settle allegations of fraud in the lab’s data, a month after Harvard the Brigham disclosed that they were calling for the retractions of more than 30 papers from the lab, and three weeks after the NIH paused a clinical trial based on the work, two leading journals have issued an expression of concern about 15 papers from the lab.

But expressions of concern are not retractions, of course. From the notice, in Circulation and Circulation Research, both of which are published by the American Heart Association: Continue reading Journals stamp expressions of concern on 15 papers from Anversa’s cardiac stem cell lab

Author lifts from one paper in two different articles. Why does one journal retract, while the other corrects?

circ resAre there instances when similarities between papers should be fixed by a correction, rather than a retraction?

We’re asking ourselves that question after seeing two journals take very different approaches to a somewhat similar situation. Last year, Frontiers in Physiology retracted a paper by Anastasios Lymperopoulos at Nova Southeastern University in Florida because of an “an unacceptable level of similarity” to a 2009 review article by different authors. But more recently, after Circulation Research discovered another paper co-authored by Lymperopoulos also contained similar text from the same 2009 review, it decided to correct the passages.

The last author of the Circulation Research paper told us the overlap between the two papers was less than 5%, and the journal never suggested the authors retract the paper.

Here’s the correction notice in Circulation Research:

Continue reading Author lifts from one paper in two different articles. Why does one journal retract, while the other corrects?

Raw files help fix 2003 figure by heart researcher accused of fraud

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A researcher accused of misconduct by an anonymous Japanese blogger has corrected a 2003 paper in Circulation Research, after providing a university investigation with the original source files.

Allegations of fraud have dogged Shokei Kim-Mitsuyama for years, and even caused him to step down from his position as editor in chief at another journal. However, Kim-Mitsuyama and his colleagues call the latest correction a “mistake,” which didn’t affect any of the paper’s conclusions.

We’ve unearthed a total of five publications co-authored by Kim-Mitsuyama that have earned corrections, the latest of which cites an investigation by the university:

Continue reading Raw files help fix 2003 figure by heart researcher accused of fraud

Investigation prompts 5th retraction for cancer researcher for “unresolvable concerns”

3.coverAn investigation at the University of New South Wales in Australia has led to a fifth retraction for a cancer researcher long accused of misconduct, due to “unresolvable concerns” with some images.

As we reported in December, UNSW cleared Levon Khachigian of misconduct, concluding that his previous issues stemmed from “genuine error or honest oversight.” Now, Circulation Research is retracting one of his papers after an investigation commissioned by UNSW was unable to find electronic records for two similar images from a 2009 paper, nor records of the images in original lab books.

Again, the retraction note affirms that this is not a sign of misconduct:

UNSW has not attributed any instance of research misconduct or responsibility for the unavailability of the original data to Professor Khachigian or to any of the authors of the publication.

Here’s the retraction note in full for “Angiotensin II-Inducible Smooth Muscle Cell Apoptosis Involves the Angiotensin II Type 2 Receptor, GATA-6 Activation, and FasL-Fas Engagement:” Continue reading Investigation prompts 5th retraction for cancer researcher for “unresolvable concerns”

Bad image prompts correction of Harvard-Brigham stem cell paper by Anversa

circresA group of Harvard stem cell researchers who already have one retraction and an expression of concern now have a correction. This one’s in Circulation Research, and it involves an image that previously had been flagged as suspicious in our comments.

The group is led by Piero Anversa, who as we reported last year is one of two researchers suing Harvard because the institution’s investigation into their work

has cost them millions in a forfeited sale of their company, and job offers.

Continue reading Bad image prompts correction of Harvard-Brigham stem cell paper by Anversa

Emory cardiology researcher up to six retractions

R. Wayne Alexander, via Emory
R. Wayne Alexander, via Emory

R. Wayne Alexander, a cardiology researcher at Emory whose lab has retracted four papers following university investigations, has notched retractions five and six.

Here’s the notice from Circulation Research: Continue reading Emory cardiology researcher up to six retractions

Cardiology journals retract five Matsubara studies

matsubaraThe American Heart Association (AHA) is retracting five studies by Hiroaki Matsubara, a former Kyoto Prefectural University cardiology researcher, that it had subjected to an expression of concern last year.

Here’s the notice: Continue reading Cardiology journals retract five Matsubara studies

Heart attack: Two cardiology retractions, plus a notice of duplication, in three different journals

circ researchWe’ve come across three notices in cardiology journals this week, so although they’re unrelated, we’re gathering them here.

Item 1, from Circulation Research: Continue reading Heart attack: Two cardiology retractions, plus a notice of duplication, in three different journals

Five papers by prominent cardiologist Hiroaki Matsubara subject to Expression of Concern

Hiroaki Matsubara

The American Heart Association, which publishes a number of journals, has issued an Expression of Concern about five papers in three of their publications, following allegations of image manipulation. All of the papers include Hiroaki Matsubara, of Kyoto Prefectural University, as a co-author.

The notice begins:

It has come to the attention of the American Heart Association (AHA), in a public manner, that there are questions concerning a number of figures in several AHA journals’ articles…

The “public manner” was three posts last year on the Abnormal Science blog, available here, here and here, alleging that images were manipulated in the manuscripts, and that histology slides were reused.

The notice continues: Continue reading Five papers by prominent cardiologist Hiroaki Matsubara subject to Expression of Concern