Category: basic life sciences retractions

JACS imaging paper “under editorial review” has been replicated, says author

JACS The author of a paper “under editorial review” at the Journal of the American Chemical Society has told us the results the paper have been replicated, contrary to claims made by a former member of her lab.

What’s more, the author said she has submitted a correction to the paper, which is currently flagged with an expression of concern, to provide uncropped images.

We originally reported on the case in February from the perspective of Roger Wong, a former chemist at Hong Kong University who said he hasn’t been able to replicate the findings out of the lab of Dan Yang, a current chemistry professor at HKU (who is female, despite the fact that “Dan” is frequently used as a male name in English). We unfortunately failed to reach Yang in February because of an email glitch; once we contacted Yang, she told us she does not believe Wong’s side of the story:

Continue reading JACS imaging paper “under editorial review” has been replicated, says author

Singapore investigation leads to another retraction, correction for Harvard research fellow

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After an investigation found evidence of misconduct, a biologist has issued a third retraction.

Sudarsanareddy Lokireddy — now a research fellow at Harvard Medical School — “admitted falsification,” a Research Integrity Officer at Nanyang Technological University in Singapore told us in December. According to The Scientist, another journal has also published a correction that the authors had requested earlier.

The newly retracted paper is “Myostatin is a novel tumoral factor that induces cancer cachexia,” published in Biochemical Journal and cited 40 times, according to Thomson Reuters Web of Science. Here’s the retraction note:

NEJM quickly corrects disclosure statement, errors in diabetes paper

NEJM LogoAfter publishing a paper about neuropathy in diabetic patients last week, The New England Journal of Medicine (NEJM) immediately corrected it after editors learned of errors and some missing disclosures within the article.

The notice explains that the sole author of the paper, “Diabetic Sensory and Motor Neuropathy,” reported incorrect doses for several medications, and received royalties for the tool to measure quality of life used in the paper. The author told us all the declarations were “discussed in detail” between him and the journal, and both parties agreed to the final decision. 

Let’s take a look at the lengthy correction notice — what some of our readers might call a “mega-correction:” Continue reading NEJM quickly corrects disclosure statement, errors in diabetes paper

Two more retractions bring total to 9 for neuroscience duo

Journal of Neuroscience CoverAfter the first author admitted to fraud, his colleagues have retracted a 2013 paper in the Journal of Neuroscience, as well as a 2015 book chapter about working memory.

The retractions come as part of a backstory of pulled papers authored by psychologist Edward Awh and his former graduate student David Anderson when he was based at the University of Oregon in Eugene. The pair retracted four papers last year after Anderson admitted to misconduct during an investigation by the U.S. Office of Research Integrity (and spoke to us about it last July). This led Awh — now based at the University of Chicago in Illinois — to take a second look at the other publications he’d co-authored with Anderson; earlier this year, Awh retracted two others, and informed us more would be coming, including the two most recent publications. 

First, let’s take a look at the retraction note for the Journal of Neuroscience paper, about remembered items and task performance: Continue reading Two more retractions bring total to 9 for neuroscience duo

How did two papers on same gene with different authors, publishers, end up with identical retraction notices?

1-s2.0-S0006291X16X00058-cov150h1Here’s an interesting case: We’ve found two retracted papers that describe the same gene, and both have nearly identical retraction notices. What’s unusual is that the two papers don’t have any authors in common, and appeared in two different journals published by two different companies.

The cause of both papers’ demise: Plagiarism, and use of unpublished data without permission “from an unnamed source,” who wishes to remain that way. The author of one of the papers confirmed to us that the unnamed source is a “3rd party service company.” Springer told us that the third party in the other paper, however, is another researcher.

It’s a puzzling case, to be sure. We think we have uncovered some of what happened, but remain slightly fuzzy on the details.

Here’s the first retraction, for “KDM3A interacted with p53K372me1 and regulated p53 binding to PUMA in gastric cancer,” originally published online September 30 by Biochemical and Biophysical Research Communications:

Continue reading How did two papers on same gene with different authors, publishers, end up with identical retraction notices?

Mistakes lead to retraction, correction of cancer papers by pair

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A series of mistakes have caused a pair of cancer researchers based in China to retract one paper and correct another.

The retraction stems from a duplication of figures in a paper about the molecular underpinnings of colorectal cancer, which the editor of the journal told us he believed was caused by honest error. The other paper was corrected after the authors realized they had published the wrong versions of multiple figures, an error which the authors say does not affect the paper’s conclusions.

This isn’t the first time the pair has had to correct the record — these changes follow a mega-correction for Jie Hong, and Jing-Yuan Fang, both of the Shanghai Jiao-Tong University, where Fang is the director of the Shanghai Institute of Digestive Disease.

Here’s the retraction note for “Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer,” published in the Journal of Pathology:

Continue reading Mistakes lead to retraction, correction of cancer papers by pair

Plant scientist Voinnet’s correction count grows to 22

nature structure molecular biologyWe have found another correction for high-profile plant scientist Olivier Voinnet, bringing his total count to 22. Voinnet, who works at ETH Zurich, also has seven retractions, a funding ban, and a revoked award.

Voinnet’s most recent corrections involve problems with figures; the same issue is cited in this latest correction notice, for “Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels.”

The correction notice in Nature Structural & Molecular Biology, issued earlier this year, explains:

Continue reading Plant scientist Voinnet’s correction count grows to 22

Three HER2-cancer review papers tagged with expressions of concern

The Oncologist Her 2 expression of concern

The Oncologist has tagged three review papers that share a first author with an expression of concern. The three papers, which have together been cited more than 1,000 times, focus on HER2, a gene that can contribute to breast cancer.

Though the papers contain errors, the conclusions — about how the HER2 gene serves as a predictive factor for breast cancer, and a target for therapies — remain unchanged, according to the EOC. The editor of the journal notes that the conclusions of the papers have been confirmed by other publications. Two of the papers are more than 10 years old, and today many patients continue to be treated with medications that target HER2, such as Herceptin.

Here’s the expression of concern:

Continue reading Three HER2-cancer review papers tagged with expressions of concern

Cell Press flags two papers after author confesses to fraud

Screen Shot 2016-04-11 at 8.45.56 PMNormally, when we see disputes over fraud allegations, it’s one author accusing another — but an unusual case at Cell has recently crossed our desk.

The journal has flagged a paper after an author confessed to committing fraud himself — but the corresponding author is disputing that confession, citing concerns about the confessor’s “motives and credibility.”

Independent labs are repeating the experiments to determine if the third author on the paper did, as he so claims, manipulate experiments. In the meantime, Cell and Molecular Cell have issued expressions of concern (EOCs) for two papers on which Yao-Yun Liang was a co-author. The notices cite an inquiry at Baylor College of Medicine, where the work was done, which was inconclusive, and recommended the journals take no action about the papers.

The EOCs are pretty much the same (both journals are published by Cell Press). Here’s the EOC that appears on “PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling,” published in 2006 by Cell and cited 251 times, according to Thomson Reuters Web of Science:

Continue reading Cell Press flags two papers after author confesses to fraud

DC court allows part of lawsuit against GW to proceed

kumarA DC court has denied part of George Washington University’s motion to dismiss a $8 million lawsuit by a biologist who claims his employer mishandled an investigation into his work.

Last spring, GW filed a motion to dismiss the case, brought forward by Rakesh Kumar, who has three retractions.  A judge has allowed the case to proceed, honoring parts of the school’s motion to dismiss, but denying most of it.

The memorandum opinion gives the specifics:

Continue reading DC court allows part of lawsuit against GW to proceed