Category: erroneous data

What to do when you make a mistake? Advice from authors who’ve been there

cpp-150After a group of researchers noticed an error that affected the analysis of a survey of psychologists working with medical teams to help pediatric patients, they didn’t just issue a retraction — they published a commentary explaining what exactly went wrong.

The error was discovered by a research assistant who was assembling a scientific poster, and noticed the data didn’t align with what was reported in the journal. The error, the authors note, was:

an honest one, a mistake of not reverse coding a portion of the data that none of the authors caught over several months of editing and conference calls. Unfortunately, this error led to misrepresentation and misinterpretation of a subset of the data, impacting the results and discussion.

Needless to say, these authors — who use their “lessons learned” to help other researchers avoid similar missteps — earn a spot in our “doing the right thing” category. The retraction and commentary both appear in Clinical Practice in Pediatric Psychology.

Their first piece of advice in “Retraction experience, lessons learned, and recommendations for clinician researchers” — assume errors will happen, and not vice versa: Continue reading What to do when you make a mistake? Advice from authors who’ve been there

Wound healing paper injured beyond repair

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Errors in the interpretation of some of the data — the result of “procedural flaws” —  are to blame for the retraction of a paper on a way to help skin grow back after injury.

The paper explores a method involving nanofibers. According to the abstract:

In this study, tilapia skin collagen sponge and electrospun nanofibers were developed for wound dressing…the collagen nanofibers stimulated the skin regeneration rapidly and effectively in vivo.

The paper was published January 19, 2015 by ACS Applied Materials and Interfaces, then retracted eight months later, in August. It has not been cited, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note:

Continue reading Wound healing paper injured beyond repair

Science publishes Voinnet’s 19th, 20th, and 21st corrections

351-6271-coverProminent plant biologist Olivier Voinnet has issued three more corrections in this week’s issue of Science.

Collectively, the papers have earned more than 1400 citations, according to Thomson Scientific’s Web of Knowledge.

By our count, he’s now at 21 corrections and seven retractions, following months of questions about his work. He’s been the subject of an investigation that found he “breached his duty of care,” and another which found evidence of scientific misconduct.

One correction goes against the recommendation of the ETH Commission to retract the paper for “well documented intentional manipulations.” According to the correction note, the incorrect figures did not “alter the data in any material way that could be construed to benefit the results and their conclusions.” That correction is the only one of the three for which Voinnet takes full responsibility.

The other two corrections place the responsibility on  Continue reading Science publishes Voinnet’s 19th, 20th, and 21st corrections

So, pot may not be as harmless as a recent study suggested

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Researchers are correcting a widely covered study that suggested chronic use of pot might not put users at risk of problems later in life.

It turns out that initial, unexpected finding — covered by Newsweek, The Washington Post, Quartz, and (of course) The Stoner’s Cookbook (now known as HERB) — wasn’t quite right, and a reanalysis found users had a small uptick in risk for psychosis. The authors have issued a lengthy correction in Psychology of Addictive Behaviors that includes some supplemental analysis, too.

Not surprisingly, the study’s findings engendered some controversy, which prompted the authors to reanalyze their data, collected from 408 males with varying levels of marijuana use, who were followed from their teens into their 30s.

Now, an American Psychological Association press release that accompanied the initial findings in August contains an editors note explaining why those aren’t quite correct:

Continue reading So, pot may not be as harmless as a recent study suggested

Here are the 10 — yes, 10 — reasons PLOS ONE retracted this paper

Screen Shot 2016-01-19 at 10.50.25 AMPLOS One is retracting a paper for overlapping with a Wikipedia page. And for containing material lifted from other sources. And for “language errors.” And for insufficient evidence that authors found the pathogens floating around in hospital air that they claimed to find.

The instances of plagiarism are a “huge problem,” each “enough for retraction on its own,” Jonathan Eisen, a microbiologist at the University of California, Davis, told us. Eisen, who posted several comments to the paper after its publication in October, added that the paper was “simply not technically sound.”

The paper — which even contains a spelling error in its title, “Metagenomic Human Repiratory Air in a Hospital Environment” — describes a gene sequencing method to screen the air in hospitals for pathogens. The retraction note lists 10 concerns with the paper: Continue reading Here are the 10 — yes, 10 — reasons PLOS ONE retracted this paper

Oops! Authors accidentally include extra patients in biopsy paper

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A paper that compared two gauges of needles to take samples of pancreatic masses has been retracted after authors unintentionally included patients from another trial.

“Randomized Trial Comparing the Flexible 19G and 25G Needles for Endoscopic Ultrasound-Guided Fine Needle Aspiration of Solid Pancreatic Mass Lesions,” published a year ago in Pancreas, notes that:

A total of 100 patients with solid pancreatic mass lesions constituted the study cohort and were randomized equally to the 2 needle groups.

The problem? According to the retraction note, some of those patients weren’t supposed to be included:

Continue reading Oops! Authors accidentally include extra patients in biopsy paper

Paper on plant immunity can’t fight off manipulation

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A paper on how plants respond to bacteria has an invader of its own — data manipulation.

The “irregularities and inappropriate data manipulation” were found in a figure produced by the first author, Ching-Wei Chen, whose LinkedIn page lists him as a student at the National Taiwan University. The authors were unable to replicate the results in the figure, according to the note.

The authors are doing more experiments to verify the main conclusion of the 2014 paper, “The Arabidopsis Malectin-Like Leucine-Rich Repeat Receptor-Like Kinase IOS1 Associates with the Pattern Recognition Receptors FLS2 and EFR and Is Critical for Priming of Pattern-Triggered Immunity,” published in The Plant Cell.

The retraction note explains the what happened in more detail:

Continue reading Paper on plant immunity can’t fight off manipulation

IVF embryo paper pulled for plagiarism, errors, lack of permissions

6A journal is pulling an article (with approval of “most” of the authors) because a similar paper had already been published in Chinese.

That wasn’t the only problem with “Aneuploidy analysis of non-pronuclear embryos from IVF with use of array CGH: a case report,” published in the Journal of Molecular Histology. 

The retraction note lists the three things that led to the paper’s retraction:

Continue reading IVF embryo paper pulled for plagiarism, errors, lack of permissions

Misidentified DNA leads authors to retract zebrafish cholesterol paper

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Authors are retracting a 2012 paper on cholesterol metabolism in zebrafish after realizing it included a case of mistaken identity in a DNA sequence crucial to some aspects of the experiment.  

A postdoc misidentified the plasmid in question after failing to fully sequence it before including it in the experiment. A technician in the lab found the mistake, last author Steven Farber, a researcher at the Carnegie Institution for Science in Maryland, explained:

When the omitted region was correctly sequenced we discovered it had an error.

He told us in a phone interview what that felt like:

We were like, holy crap.

Next came months of back and forth with the journal, discussing whether to correct or retract the paper. Farber tells us the mistake, which affects two figures,

was unfortunate. Most of the paper is in fact correct.

The paper, “Visualization of Lipid Metabolism in the Zebrafish Intestine Reveals a Relationship between NPC1L1-Mediated Cholesterol Uptake and Dietary Fatty Acid,” published in Chemistry & Biology, has been cited 21 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the detailed retraction note:  Continue reading Misidentified DNA leads authors to retract zebrafish cholesterol paper

New developments cause authors to pull paper on drugs’ environmental impact

integrated envThe authors of an article about the effects of pharmaceutical drugs on the environment have retracted it before publishing the final version due to new developments in the field, which would have required a major revision.

The authors pulled the paper from Integrated Environmental Assessment and Management before it went through the final publication process – such as copyediting and proofreading – after they learned about new findings related to assessing to the risks of human exposures to pharmaceuticals in the environment.

We’d try to figure out which portions of the paper might need updating, but publisher Wiley recently pulled the original article and abstract, against the journal editor’s wishes.

Here’s the retraction note: Continue reading New developments cause authors to pull paper on drugs’ environmental impact