So, pot may not be as harmless as a recent study suggested

adb-150

Researchers are correcting a widely covered study that suggested chronic use of pot might not put users at risk of problems later in life.

It turns out that initial, unexpected finding — covered by Newsweek, The Washington Post, Quartzand (of course) The Stoner’s Cookbook (now known as HERB) wasn’t quite right, and a reanalysis found users had a small uptick in risk for psychosis. The authors have issued a lengthy correction in Psychology of Addictive Behaviors that includes some supplemental analysis, too.

Not surprisingly, the study’s findings engendered some controversy, which prompted the authors to reanalyze their data, collected from 408 males with varying levels of marijuana use, who were followed from their teens into their 30s.

Now, an American Psychological Association press release that accompanied the initial findings in August contains an editors note explaining why those aren’t quite correct:

Continue reading So, pot may not be as harmless as a recent study suggested

Here are the 10 — yes, 10 — reasons PLOS ONE retracted this paper

Screen Shot 2016-01-19 at 10.50.25 AMPLOS One is retracting a paper for overlapping with a Wikipedia page. And for containing material lifted from other sources. And for “language errors.” And for insufficient evidence that authors found the pathogens floating around in hospital air that they claimed to find.

The instances of plagiarism are a “huge problem,” each “enough for retraction on its own,” Jonathan Eisen, a microbiologist at the University of California, Davis, told us. Eisen, who posted several comments to the paper after its publication in October, added that the paper was “simply not technically sound.”

The paper — which even contains a spelling error in its title, “Metagenomic Human Repiratory Air in a Hospital Environment” — describes a gene sequencing method to screen the air in hospitals for pathogens. The retraction note lists 10 concerns with the paper: Continue reading Here are the 10 — yes, 10 — reasons PLOS ONE retracted this paper

List of retractions, corrections grows for Duke researchers

cov200hDuke researcher Michael Foster and his former co-author Erin Potts-Kant are adding to their notice count with a major correction from late last year to a paper on how certain cells in mice respond to a pneumonia infection, citing “potential discrepancies in the data.”

The correction is actually a partial retraction: The note explains that parts of three figures should be discounted.

We’ve also recently unearthed multiple corrections and two retractions from the pair that we missed from earlier in 2015.

After questions about the data in the corrected paper arose, the authors were able to replicate most of the experiments in the paper, according to the note. But since the paper was published, the senior author passed away, closing her lab, so they couldn’t repeat all of the work.

Here’s the correction notice for “Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)−/− mice,” published in The Journal of Allergy and Clinical Immunology:

Continue reading List of retractions, corrections grows for Duke researchers

Oops! Authors accidentally include extra patients in biopsy paper

Screen Shot 2015-12-30 at 2.06.59 PM

A paper that compared two gauges of needles to take samples of pancreatic masses has been retracted after authors unintentionally included patients from another trial.

Randomized Trial Comparing the Flexible 19G and 25G Needles for Endoscopic Ultrasound-Guided Fine Needle Aspiration of Solid Pancreatic Mass Lesions,” published a year ago in Pancreas, notes that:

A total of 100 patients with solid pancreatic mass lesions constituted the study cohort and were randomized equally to the 2 needle groups.

The problem? According to the retraction note, some of those patients weren’t supposed to be included:

Continue reading Oops! Authors accidentally include extra patients in biopsy paper

Data dispute forces journal to pull paper about rare bird on valuable land

coverThe authors of a paper about the density of an endangered bird on valuable Texas lands are disputing the journal’s decision to pull the paper after other scientists objected to some of its contents.

The paper, published online in August by the Journal of Field Ornithology, compared different models for estimating the number of golden-cheeked warblers that nest in Texas. According to the Austin American-Statesman, some of that land includes highly sought-after woodlands. Developers had used estimates from recent years, which suggested that the bird population was in relatively good health, to petition to open that land for real estate development. But the new paper concluded that those estimates were too high.

After some scientists who produced the more rosy estimates claimed that the some of their data had been included in the newest paper without permission, the editor in chief decided to retract it.

That was in November. There’s no retraction note for “Density influences accuracy of model-based estimates for a forest songbird.” We contacted the editor in chief, Gary Ritchison, to ask why. He told us,

Continue reading Data dispute forces journal to pull paper about rare bird on valuable land

Cancer Cell paper under investigation following anonymous queries on PubPeer

cancer cell

A Cancer Cell paper that caused a flurry of activity on the website PubPeer is under investigation, after the last author announced on the site that he’d requested a correction from the journal.

The 2012 paper sparked a lively dialogue last month on the post-publication discussion site, as commenters questioned Western blot images in which some bands appeared to be duplicates. The last author responded, noting he had alerted the journal to a “mishap,” and a correction would be forthcoming. However, some commenters remained unsatisfied, and questioned why the correction was taking so long to appear, as well as the explanation for what went wrong.

A spokesman from Cancer Cell confirmed to us the paper is under investigation:

Continue reading Cancer Cell paper under investigation following anonymous queries on PubPeer

Science retracting paper by chemists cut off from NSF funding

Bruce Eaton
Bruce Eaton

feldheim
Daniel Feldheim

The National Science Foundation will no longer fund a pair of chemists who “recklessly falsified data,” according to a report from the NSF’s Office of Inspector General, unless they “take specific actions to address issues” in a 2004 Science paper.

That paper is going to be retracted as soon as possible, Science told us. The co-authors that the NSF reprimanded are Bruce Eaton and Dan Feldheim, now at the University of Colorado at Boulder; they have been under scrutiny since 2008, when an investigation at North Carolina State University, their former employer, found that the Science paper contained falsified data.

The paper, “RNA-Mediated Metal-Metal Bond Formation in the Synthesis of Hexagonal Palladium Nanoparticles,” has been cited 138 times.

Science Editor in Chief  Marcia McNutt told us today that a retraction is in the works:

Continue reading Science retracting paper by chemists cut off from NSF funding

Misidentified DNA leads authors to retract zebrafish cholesterol paper

cov150h

Authors are retracting a 2012 paper on cholesterol metabolism in zebrafish after realizing it included a case of mistaken identity in a DNA sequence crucial to some aspects of the experiment.  

A postdoc misidentified the plasmid in question after failing to fully sequence it before including it in the experiment. A technician in the lab found the mistake, last author Steven Farber, a researcher at the Carnegie Institution for Science in Maryland, explained:

When the omitted region was correctly sequenced we discovered it had an error.

He told us in a phone interview what that felt like:

We were like, holy crap.

Next came months of back and forth with the journal, discussing whether to correct or retract the paper. Farber tells us the mistake, which affects two figures,

was unfortunate. Most of the paper is in fact correct.

The paper, “Visualization of Lipid Metabolism in the Zebrafish Intestine Reveals a Relationship between NPC1L1-Mediated Cholesterol Uptake and Dietary Fatty Acid,” published in Chemistry & Biology, has been cited 21 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the detailed retraction noteContinue reading Misidentified DNA leads authors to retract zebrafish cholesterol paper

Suspicions of data manipulation lead to correction of testicular cancer paper

Screen Shot 2015-12-10 at 5.20.23 PM

The corresponding author of a paper on testicular cancer is telling readers to discount a figure after she learned it may have been manipulated.

Although that one figure in the 2005 paper in the British Journal of Cancer may be problematic, the authors found data to support the other figures, and its conclusions.

This isn’t the first time first author Kerry Manton has faced questions over her data — in 2012, one of her papers was retracted following an investigation by her institution, the Queensland University of Technology. And in 2014, QUT repaid a $275,000 grant after finding Manton

failed to fulfill (her) responsibilities in relation to the responsible dissemination of research findings and that this, coupled with a failure to correct the errors, constituted research misconduct.

Here’s the corrigendum for “Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis:”

Continue reading Suspicions of data manipulation lead to correction of testicular cancer paper

Retractions follow misconduct by biologist, one more on the way

Screen Shot 2016-01-06 at 11.11.12 AM

Two journals have retracted papers by a biologist at the University of Tokyo who admitted to scientific misconduct, including data duplication and misrepresentation. Another journal is planning to retract one of the researcher’s papers later this month.

Hyun Kim studies a protein known as the “ski protein.” However, one analysis of the role of ski protein in development was retracted late last month by the Asian-Australasian Journal of Animal Sciences. The journal decided to investigate after Kim admitted to misconduct in two other papers published in a different journal.

Here’s the note for the paper:

Continue reading Retractions follow misconduct by biologist, one more on the way