Data fabrication by ex-Harvard researcher takes down paper on Huntington’s disease

A researcher at Harvard Medical School and Massachusetts General Hospital is retracting a paper due to “inappropriate manipulation and fabrication of data” by the first author.

According to the retraction notice, published Aug. 22, corresponding author Marian DiFiglia is retracting the paper because the alleged misconduct by the first author, Antonio Valencia:

led to an incorrect conclusion in the paper that NADPH activity is elevated in Huntington’s disease (HD). Some original data were missing and efforts to replicate findings using the reported method or an alternative approach were unsuccessful. An institutional faculty panel supports the decision and the reasons for the retraction.

The notice added that the alleged data manipulation and fabrication affected bar graphs in two of the paper’s figures.

Terri Ogan, a spokesperson for Mass General, told Retraction Watch that Valencia no longer works at the institution, but declined to say whether there has been an investigation into the alleged misconduct: Continue reading Data fabrication by ex-Harvard researcher takes down paper on Huntington’s disease

Authors retract Science paper after investigation reveals manipulated images

Researchers at a prominent Japanese university have retracted a 2015 paper in Science, after an investigation uncovered image falsification and fabrication.

Last September, the University of Tokyo began an investigation of seven papers from the lab of cell biologist Yoshinori Watanabe after receiving anonymous allegations. In May 2017, the university determined that five papers contained falsified or fabricated images, and announced the results of its investigation on August 1. Two of the papers were published in Science, two in Nature and one in EMBO Reports.

On July 1 2017, EMBO Reports issued an erratum to the 2011 paper flagged in the investigation, correcting issues in several figures. Here’s the retraction notice for “The inner centromere–shugoshin network prevents chromosomal instability,” the 2015 paper in Science and the first of the papers to be retracted: Continue reading Authors retract Science paper after investigation reveals manipulated images

Amid legal battle, psych journal issuing caution about torture paper

A psychology journal plans to issue an editor’s note about a controversial paper exploring what the author called “the biggest scandal to hit” the American Psychological Association (APA) in years.

The note cautions readers that the subject of the paper, published in the SAGE journal Teaching of Psychology, is part of a pending lawsuit, and that “teachers considering using the article in their classrooms” should watch for developments in the case.   Continue reading Amid legal battle, psych journal issuing caution about torture paper

“Scientifically misleading errors” prompt authors to withdraw paper

A group of authors have withdrawn a paper after revealing a litany of issues to the journal that published it. Among those issues were “scientifically misleading errors,” “insufficient” validation, and a disagreement between the researchers on whether it should have been published at all.

Optimal DNA structure of reverse-hairpin beacons for label-free and positive surface enhanced Raman scattering assays,” originally published in June in Optical Materials Express (OMEx), was retracted Aug. 7. The paper purported to describe a detection method for RNA associated with influenza virus. It has not yet been cited, according to Clarivate Analytics’ Web of Science.

Here’s the full list of issues cited in the retraction notice: Continue reading “Scientifically misleading errors” prompt authors to withdraw paper

Case closed? Fired Pfizer researcher slated for seven retractions

Pfizer has discovered two additional papers that merit retraction from the lab of a former employee. One of the papers, published in Clinical Cancer Research, was retracted earlier this month.

Last year, Pfizer requested retractions of five papers from the lab of breast cancer researcher Min-Jean Yin, who was fired after an investigation revealed image duplication. The papers were first questioned on PubPeer. By April 2017, all five papers had been retracted.

After the initial probe, the pharmaceutical giant conducted a follow-up review of papers originating from Yin’s lab (which Leonid Schneider posted about on May 23). A spokesperson for the company told us that the review revealed two more articles that merited retraction “in light of data integrity issues relating to the figures therein.” The 2013 paper in Clinical Cancer Research was retracted earlier this month at Pfizer’s request. On May 1, 2017, Pfizer asked PLOS ONE to retract 2013 paper. Continue reading Case closed? Fired Pfizer researcher slated for seven retractions

Publisher flags paper on same-sex parenting after neo-Nazi group cites it

A publisher has issued an expression of concern (EoC) about a study that claimed children with same-sex parents were at greater risk of depression and abuse, after posters using statistics from the paper to support a homophobic message appeared in Australia and the US.

On Aug. 21, several news websites reported that these posters were appearing in Melbourne, Australia, citing claims from a 2016 paper published in Depression Research and Treatment, which said that children with same-sex parents are more at risk for depression, abuse, and obesity than children with opposite-sex parents. The poster had also appeared previously in Minneapolis and has been traced to a neo-Nazi group, as reported by HuffPost Australia. Australia is preparing for a national, non-binding, mail-in vote on whether to provide marriage equality for same-sex couples.

The EoC mechanism, which was chosen by the journal’s publisher, Hindawi, is an unusual choice here. The paper’s author, D. Paul Sullins, a sociology professor at The Catholic University of America and the paper’s author, told Retraction Watch that Hindawi contacted him Aug. 21 about the decision. Initially, he told us he didn’t have any “particular objection to it,” but later told us he changed his mind after he read more about COPE’s guidelines for EoCs: Continue reading Publisher flags paper on same-sex parenting after neo-Nazi group cites it

Given “wrong pathology slides,” heart journal retracts paper

A cardiology journal has retracted a paper after the authors were unable to provide correct pathology slides to replace the wrong ones submitted with the original manuscript.

The paper is titled “Aortic Valve Endocarditis and Coronary Angiography With Cerebral Embolic Protection,” published on April 10, 2017 in The Journal of the American College of Cardiology: Cardiovascular Interventions (JACC:CI). It has not yet been cited, according to Clarivate Analytics’ Web of Science.

JACC:CI retracted the paper on Aug. 14, providing this notice: Continue reading Given “wrong pathology slides,” heart journal retracts paper

What should a journal do when a scientist who committed misconduct submits a new paper?

Chris Surridge

In December of last year, Chris Surridge found himself in a situation not uncommon to journal editors: A researcher who had been found to have committed misconduct had submitted a manuscript to the journal Surridge edits, Nature Plants. Retraction Watch readers may recall the name of the corresponding author, Patrice Dunoyer, who has had five papers retracted and five corrected following an investigation into work out of the Olivier Voinnet lab.

So what to do? The journal accepted the paper in May, and published it in June, along with a thoughtful editorial likening prizes and cheating in science to those phenomena in sports. The editors, according to the editorial, “treated the study we received as we would any other.” We asked Surridge to answer a few questions about the episode.

Retraction Watch (RW): Was there some internal debate about whether to consider publishing a paper by Dr. Dunoyer? Did you personally hesitate? Why or why not? Continue reading What should a journal do when a scientist who committed misconduct submits a new paper?

Former MD Anderson researcher objects to retraction of his paper

A cell biology journal has retracted a 2016 paper after an investigation revealed that the corresponding author failed to include two co-authors and acknowledge the funding source.

According to the retraction notice, the Journal of Cellular Physiology retracted the paper after the University of Texas, MD Anderson Cancer Center found that last author Jin Wang had omitted two researchers from the list of authors, and had also failed to acknowledge funding from the U.S. National Institutes of Health (NIH).

But Wang tells a different story. Continue reading Former MD Anderson researcher objects to retraction of his paper

“Data had been manipulated,” again: Swiss probe prompts two more retractions

A biologist at the University of Basel is retracting two papers, citing data manipulation uncovered during an institutional investigation. That investigation has already led to the retraction of a paper in Science Translational Medicine by some of the same authors earlier this year.

The two latest retractions, in the Journal of Biological Chemistry (JBC), share the same  corresponding author — Michael Sinnreich, based at University of Basel — and first author, Bilal Azakir, who is now an assistant professor at Beirut Arab University. The retraction notices cite an investigation at the University of Basel.

Here’s the retraction notice for “Proteasomal inhibition restores biological function of mis-sense mutated dysferlin in patient-derived muscle cells:” Continue reading “Data had been manipulated,” again: Swiss probe prompts two more retractions