Researchers decry study warning of low-carb diet risks

Nutrition and DiabetesAdvocates of low-carbohydrate diet are voicing concern about a recent paper that suggested the diet could cause weight gain, contrary to previous research. One expert has even called for its retraction.

The study, published in Nutrition & Diabetes in February, also found that the low-carb diet did little to prevent the progression of type 2 diabetes. Researchers have since criticized the study for drawing these conclusions based on data from a handful of mice, using a poor proxy for the human version of the diet.

One expert took to social media to warn against the study’s message regarding the low-carb, high-fat diet (LCHF); for instance, obesity & nutrition researcher and author, Zoë Harcombe from Newport, Wales, tweeted: Continue reading Researchers decry study warning of low-carb diet risks

Neuroscientist pleads guilty in court to fraud, gets two-year suspended sentence

Bruce Murdoch
Bruce Murdoch

A Parkinson’s researcher pleaded guilty to fraud in court this morning in Brisbane, Australia, and received a two-year suspended sentence.

Court sentences for fraud are rare, to say the least. This one follows an investigation by Bruce Murdoch‘s former employer, the University of Queensland, into 92 papers — resulting in the retraction of three papers co-authored by Caroline Barwood, also facing fraud charges. The investigation was unable to find any evidence that published research cited in court had been ever carried out.

The Australian reported this morning that Murdoch:

Continue reading Neuroscientist pleads guilty in court to fraud, gets two-year suspended sentence

How does an abstract get published without any of the authors knowing?

369Thrombosis Research has removed an abstract after all seven authors authors listed did not know that it had been submitted for publication.

We’ve seen many instances of some authors not being in on a submission, but a case in which all of the authors are in the dark? That’s new to us.

A spokesperson for Elsevier, the journal’s publisher, told us that the organizers of a conference submitted it to the journal as part of a supplement for a meeting, unbeknownst to the authors.

Here’s the odd “removal notice” for “The Characterisation of the Age-Specific Differences in Platelet Physiology and Function:”

Continue reading How does an abstract get published without any of the authors knowing?

Firefly paper flagged following Queensland investigation

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A BMC journal has added an expression of concern to a paper on firefly genes after a University of Queensland investigation determined a table should be credited to a different source.

According to a representative of the university, the investigation found no evidence of misconduct. The university submitted an erratum that the journal chose not to publish; in the EOC note, the journal says the wording of the erratum is “under dispute.”

The erratum submitted to the journal specifies that the table should be attributed to former UQ biologist Robert Birch, who was not an author on the paper. The investigation concluded that the authors had not committed misconduct and “acted in good faith” in using the table, Anton Middelberg, University of Queensland Pro-Vice-Chancellor told us.

The paper, “Synthetic versions of firefly luciferase and Renilla luciferase reporter genes that resist transgene silencing in sugarcane, published in BMC Plant Biology, has been cited twice, according to Thomson Scientific’s Web of Knowledge.

Here’s the expression of concern:

Continue reading Firefly paper flagged following Queensland investigation

8th retraction appears for researcher who faked patient records

S00219150An 8th paper has been retracted for Anna Ahimastos, a heart researcher who faked patient records.

It’s the last in a chain of retractions that were the result of an investigation by her former workplace, Baker IDI Heart & Diabetes Institute in Australia. As with the others, she did not agree to the retraction.

The investigation found fabricated patients records in some papers; in other papers, such as the newly retracted 2010 study in Atherosclerosis, the original data source could not be verified.  The latest retraction — “A role for plasma transforming growth factor-β and matrix metalloproteinases in aortic aneurysm surveillance in Marfan syndrome?” — followed up on a previous clinical trial, examining how a blood pressure drug might help patients with a life-threatening genetic disorder.

That previous trial — which also included 17 patients with Marfan syndrome treated with either placebo or perindopril — has been retracted from JAMA; the New England Journal of Medicine has also retracted a related letter.

The latest retraction note conveys similar information to the other perindopril/Marfan syndrome retractions: Continue reading 8th retraction appears for researcher who faked patient records

Investigation prompts 5th retraction for cancer researcher for “unresolvable concerns”

3.coverAn investigation at the University of New South Wales in Australia has led to a fifth retraction for a cancer researcher long accused of misconduct, due to “unresolvable concerns” with some images.

As we reported in December, UNSW cleared Levon Khachigian of misconduct, concluding that his previous issues stemmed from “genuine error or honest oversight.” Now, Circulation Research is retracting one of his papers after an investigation commissioned by UNSW was unable to find electronic records for two similar images from a 2009 paper, nor records of the images in original lab books.

Again, the retraction note affirms that this is not a sign of misconduct:

UNSW has not attributed any instance of research misconduct or responsibility for the unavailability of the original data to Professor Khachigian or to any of the authors of the publication.

Here’s the retraction note in full for “Angiotensin II-Inducible Smooth Muscle Cell Apoptosis Involves the Angiotensin II Type 2 Receptor, GATA-6 Activation, and FasL-Fas Engagement:” Continue reading Investigation prompts 5th retraction for cancer researcher for “unresolvable concerns”

Math journal retracts entire issue following peer-review problems

home_coverThe editor of a special issue of a math journal — and author of many of the papers in it — has officially retracted the entire thing, after promising to withdraw it last year following issues with the review process.

According to the note in Mathematics and Mechanics of Solids, the peer-review process was “less rigorous than the journal requires.” Indeed, that process was coordinated by guest editor David Y. Gao, a mathematician at the Federation University Australia, who was also author on 11 of the 13 papers present in the issue.

Gao told us in November that he was withdrawing the issue because he thought it would be better suited as a book.

Here is the official retraction note, which focuses on the conflict of interest:

Continue reading Math journal retracts entire issue following peer-review problems

Suspicions of data manipulation lead to correction of testicular cancer paper

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The corresponding author of a paper on testicular cancer is telling readers to discount a figure after she learned it may have been manipulated.

Although that one figure in the 2005 paper in the British Journal of Cancer may be problematic, the authors found data to support the other figures, and its conclusions.

This isn’t the first time first author Kerry Manton has faced questions over her data — in 2012, one of her papers was retracted following an investigation by her institution, the Queensland University of Technology. And in 2014, QUT repaid a $275,000 grant after finding Manton

failed to fulfill (her) responsibilities in relation to the responsible dissemination of research findings and that this, coupled with a failure to correct the errors, constituted research misconduct.

Here’s the corrigendum for “Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis:”

Continue reading Suspicions of data manipulation lead to correction of testicular cancer paper

Cancer researcher cleared of misconduct, inquiry finds “genuine error or honest oversight”

Khachigian
Levon Khachigian

An investigation at the University of New South Wales in Australia has determined that a long-accused cancer researcher did not commit misconduct.

The investigation did find instances when Levon Khachigian breached the code of conduct, but Continue reading Cancer researcher cleared of misconduct, inquiry finds “genuine error or honest oversight”

7th retraction for heart researcher who faked patient records

1.coverAnna Ahimastos, a heart researcher who faked patient records, has notched her 7th retraction.

One more paper is expected to be retracted, according to a spokesperson from her former institution, the Baker IDI Heart & Diabetes Institute in Australia.

As with the other retractions, the 2005 paper in Hypertension — about how the hypertension drug ramipril may help alleviate cardiovascular disease — is being pulled after Ahimastos admitted to scientific misconduct. She asserts the data remain valid, and has not signed the retraction notice.

The Hypertension paper has been cited 63 times, according to Thomson Scientific’s Web of Knowledge. Here’s the retraction note in full (the language will be familiar to readers who have been following this case):

Continue reading 7th retraction for heart researcher who faked patient records