Author: Dalmeet Singh Chawla

Data were “fraudulently obtained” in epilepsy paper, probe finds

brain-research-bulletinA brain research journal has retracted a 2016 study about epilepsy after an institutional investigation determined that some of the data were taken from another published paper.

The retraction notice for the study — which appeared in Brain Research Bulletin — cites an investigation by the scientific integrity committee at Tongji University in Shanghai, China, which concluded the authors had engaged in “unethical publishing behavior.”

Here’s the retraction notice for “Clc-2 knockout attenuated experimental temporal lobe epilepsy in mice by tonic inhibition mediated by GABAA receptors:” Continue reading Data were “fraudulently obtained” in epilepsy paper, probe finds

Error in one line of code sinks cancer study

journl-of-clinical-oncologyAuthors of a 2016 cancer paper have retracted it after finding an error in one line of code in the program used to calculate some of the results.

Sarah Darby, last author of the now-retracted paper from the University of Oxford, UK, told Retraction Watch that the mistake was made by a doctoral student. When the error was realized, Darby said, she contacted the Journal of Clinical Oncology (JCO), explained the issue, and asked whether they would prefer a retraction or a correction. JCO wanted a retraction, and she complied.

The journal allowed the authors to publish a correspondence article outlining their new results.

Here’s the lengthy retraction notice, published online last month: Continue reading Error in one line of code sinks cancer study

Authors retract two papers on shock therapy, citing language barriers

the-journal-of-ectAn electroconvulsive therapy (ECT) journal has retracted two 2016 papers after uncovering problems in the data analyses, which the author says were due to language barriers.

Interestingly, two authors of the newly retracted papers — Yu-Tao Xiang from the University of Macau in China and Gabor Ungvari from the University of Western Australia — also recently co-authored another paper on an entirely different topic that has received a lengthy correction. That paper — on the use of organs from executed prisoners in China — raised controversy for allegedly reporting a “sanitized” account of the practice. The correction notice, in the Journal of Medical Ethics, was accompanied by a critics’ rebuttal to the paper.

According to Xiang, the newly retracted papers in The Journal of ECT — which examined the efficacy of ECT in treating schizophrenia — were pulled due to “genuine errors” resulting from differences in language. All the authors agree with the retraction, Xiang noted. 

Xiang told us: Continue reading Authors retract two papers on shock therapy, citing language barriers

Finnish institute finds no evidence to support misconduct in diabetes paper

VTT Research CentreAn investigation at the VTT Technical Research Centre of Finland has found no evidence of misconduct by one of its former researchers in a diabetes paper.

We previously reported on the case after the VTT was accused of cutting corners in a previous investigation into Matej Orešič (now based at the Steno Diabetes Center in Gentofte, Denmark). In 2014, the VTT concluded that there was no evidence of falsification or data tampering on the part of Orešič in the 2008 paper published in the Journal of Experimental Medicine (JEM). The proceedings came into the public domain through a news article published in the Finnish media outlet Helsingin Sanomat in February 2016, which prompted the VTT to reopen the case.

Now, the same people who questioned the previous investigation told us they have doubts about the latest conclusions, noting the probe should not have focused on a single paper, but rather on alleged problems within the plasma and serum metabolomics group, previously led by Orešič.

Orešič sent us this report, which the VTT released on June 15, outlining their decision. The VTT confirmed the legitimacy of the report, which says: Continue reading Finnish institute finds no evidence to support misconduct in diabetes paper

Amid controversial Sarepta approval decision, FDA head calls for key study retraction

FDAThe head of the U.S. Food and Drug Administration (FDA) has called for the retraction of a study about a drug that the agency itself approved earlier this week, despite senior staff opposing the approval.

On September 19, the FDA okayed eteplirsen to treat Duchenne muscular dystrophy (DMD), a rare genetic disorder that results in muscle degeneration and premature death. Several of its top officials disagreed with the drug’s approval, questioning how beneficial it will be for patients, as Forbes, MedPage Today and others reported.

In a lengthy report Commissioner Robert Califf sent to senior FDA officials on September 16 — that was made public on September 19 — he called for the retraction of a 2013 study published in Annals of Neurology funded by the seller of eteplirsen, which showed beneficial effects of the drug in DMD patients. Califf writes in the report:

Continue reading Amid controversial Sarepta approval decision, FDA head calls for key study retraction

Researcher in Ireland loses two 13-year old studies

journal-of-biological-chemistryThe Journal of Biological Chemistry (JBC) has retracted two 2003 studies after concluding that figures in the papers had been duplicated, and portions of some figures in one paper “did not accurately represent the results of the experimental conditions.”

The two newly retracted papers have the same last author — Therese Kinsella, a biochemist at the University College Dublin (UCD), who told us the data have been upheld by subsequent research, but that she supports the retractions, which are now part of a UCD investigation.

The retractions will bring up some familiar names: The first author on one of the papers is Sinéad Miggin from Maynooth University in the Republic of Ireland; in 2014, Miggin logged two retractions in the JBC, which triggered an investigation into co-author Aisha Qasim Butt. Last year, Maynooth University revoked Butt’s PhD after she admitted to “falsification and misrepresentation” of data in both studies as well as her PhD thesis. At the time, Miggin and two other researchers were fully exonerated by Maynooth University from “any wrongdoing.”

Butt, however, is not an author of either of the newly retracted papers. Although Butt’s LinkedIn page still lists her as a postdoctoral researcher at UCD, a spokesperson from the institution told us she is no longer based there.

We don’t often see such old papers retracted. Kaoru Sakabe, Manager of Publishing Issues at the American Society for Biochemistry and Molecular Biology, which publishes JBC, told us how this decision came about: Continue reading Researcher in Ireland loses two 13-year old studies

Would peer review work better if reviewers talked to each other?

katherine-brown
Katherine Brown

Would distributing all reviewers’ reports for a specific paper amongst every referee before deciding whether to accept or reject a manuscript make peer review fairer and quicker? This idea — called “cross-referee commenting” — is being implemented by the journal Development, as part of its attempt to improve the peer-review process. Katherine Brown, executive editor of Development from Cambridge, UK, who co-authored a recent editorial about the phenomenon, spoke to us about the move. 

Retraction Watch: Many journals share the reviews of a particular paper with those who’ve reviewed it. What is cross-referee commenting in peer review and how is it different from current reviewing processes? Continue reading Would peer review work better if reviewers talked to each other?

Renewable energy researcher with troubled record loses another paper

renewable-sustainable-energy-reviewsA renewable energy researcher who recycled material in several papers — and has already agreed to withdraw 10 studies — has lost another paper.

In January, we reported that six of 10 papers flagged by an investigation into author Shyi-Min Lu have either been retracted or withdrawn. Now, Lu has lost another paper that was not among the previous ten — again, for reproducing figures from earlier works without seeking permission from original authors. This paper was on a hot topic: gas hydrates, considered to be a potential new energy source to replace oil in the 21st century.

The investigations into Lu’s work took place at the Industrial Technology Research Institute in Hsinchu, Taiwan, where he was formerly based, and the National Taiwan University, in Taipei, Taiwan, which fired Lu from his position at the university’s energy research center.

Here’s the retraction notice in Renewable and Sustainable Energy Reviews, issued last month: Continue reading Renewable energy researcher with troubled record loses another paper

Journal to retract study declaring safety of asbestos roofs: Report

joehOnly a few months after publication, an environmental journal has told an activist group it plans to retract a paper about the safety of roofing products containing asbestos after facing heavy criticism.

This summer, Journal of Occupational and Environmental Hygiene (JOEH) received multiple letters asking the to retract the paper. Critics of the paper — which concluded that exposures to asbestos-containing roofing products were within safety limits — argued the article provided misleading information, grouped different materials with different asbestos exposures together, and failed to note the approving editor’s ties to the asbestos industry.

The article was published as a case study, which is considered a type of “column” by the journal, thereby bypassing its peer-review system; according to an email the journal sent to the organization Right on Canada (which a representative forwarded to Retraction Watch), this served as the basis for the journal’s decision to pull the paper.

According to the email, the journal’s editorial board decided on August 10 to retract “Airborne asbestos exposures associated with the installation and removal of roofing products” due to

Continue reading Journal to retract study declaring safety of asbestos roofs: Report

Authors retract 2016 cancer study when data don’t align with figures

cell-death-and-differentiationResearchers have retracted a 2016 cancer study, citing discrepancies between the data and images presented in the paper. 

Although the retraction notice itself contains relatively little information, we’ve obtained a letter from the last author — Jun-Li Luo of The Scripps Research Institute in Jupiter, Florida — to the editor-in-chief of Cell Death and Differentiation that says a bit more. 

According to the letter, after receiving the anonymous email, Luo conducted an investigation, contacting co-authors who contributed each of the figures in question. Although Luo writes that he has no reason to suspect fraud, the researchers were not able to provide some of the original data.

PubPeer commenters have questioned figures 1, 3, 4, 5, 6 and 7 in the study, “IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.”

In the letter, Luo tells Gerry Melino, co-editor-in-chief of the journal from the University of Leicester, UK, that figures 3D and 3E were provided by the study’s first author, Xing Fang, adding: Continue reading Authors retract 2016 cancer study when data don’t align with figures