Category: clinical study retractions

Biologist under investigation asks journal to swap image, journal retracts the paper

Suchitra Sumitran-Holgersson, via the University of Gothenburg
Suchitra Sumitran-Holgersson, via the University of Gothenburg

When a researcher discovered one of the images in her papers was a duplication, she asked the journal to fix it — but the journal decided to retract the paper entirely.

The researcher, Suchitra Sumitran-Holgersson, is currently being investigated by the University of Gothenburg in Sweden after a number of her papers were questioned on PubPeer. She told us the duplication was the result of ‘‘genuine human error.’’ Tissue Engineering Part A, however, decided the request to swap the image was a ‘‘cause for concern,’’ and chose to retract the paper. 

Here’s the retraction notice:

Continue reading Biologist under investigation asks journal to swap image, journal retracts the paper

Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

PLOS OneA pair of Duke researchers who each have more than 10 retractions have earned some more.

Both of the newly retracted papers — originally published in 2012 by PLOS ONE — list Erin Potts-Kant as a co-author; one includes her former supervisor, Michael Foster, as lead author. The pair has since left Duke (Potts-Kant was arrested for using school credit cards to shop at the likes of Target, and Foster retired). The reason provided for these retractions will be familiar to anyone who’s been following their case — there were “concerns about the reliability” of the data.

By our count, Potts-Kant now has 14 retractions, making her one of the few women to hold a position on our leaderboard.

Here’s the retraction notice for “Iron Supplementation Decreases Severity of Allergic Inflammation in Murine Lung,” a paper that lists both Foster and Potts-Kant as authors:

Continue reading Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

Non-retraction notice: Editors explain why two similar papers aren’t redundant

abdominal radiologyEditors have published a notice to let readers know why they’re not retracting a couple of papers.

One paper examined whether the results of CT scans could be used to stage patients with uterine carcinoma; the other considered whether CT scans could be used to predict overall survival in uterine carcinoma. Both papers — by researchers at the Memorial Sloan Kettering Cancer Center — used data from the same 193 women. After they appeared in in different journals, the editors considered whether they were redundant — a quality that can spell retraction for a paper.

The editors explain why they decided the papers were unique in a brief commentary — a non-retraction notice, if you will — published in a third journal, Abdominal Radiology:

Continue reading Non-retraction notice: Editors explain why two similar papers aren’t redundant

Former Pitt postdoc admits to faking data

pittA former postdoc at the University of Pittsburgh has admitted to committing research misconduct in published papers and in National Institutes of Health (NIH) grant applications.

The Office of Research Integrity (ORI) said on Friday that Kenneth Walker, who was studying the development of the urinary tract,  Continue reading Former Pitt postdoc admits to faking data

Researcher who unsuccessfully sued journal to stop retractions earns another expression of concern

Mario Saad
Mario Saad

A journal has added expressions of concern (EOCs) to four papers about diabetes, including one co-authored by an author who previously sued a different journal when it took a similar action on his papers.

The Journal of Physiology flagged the papers after an investigation “could not rule out the possibility” that they contained duplicated Western blots. Though the three other papers do not include Mario Saad on their author list, he plays a role: The papers include blots duplicated from other papers of Saad’s. And they reveal that Saad may have published those blots multiple times in his own work.

The EOCs all start out with the same statement: Continue reading Researcher who unsuccessfully sued journal to stop retractions earns another expression of concern

Study on pregnant women with HIV lied about having ethics approval

Screen Shot 2016-04-12 at 5.47.50 AMWe recently discovered a relatively old retraction notice — from 2014 — of a study on pregnant women with HIV.

The paper was retracted two years ago when BMC Research Notes discovered the authors falsely claimed they had obtained ethics approval from an institution in Kenya.

The study looked at the effectiveness of an antiretroviral therapy in 50 women who were receiving care at a center in Nairobi, Kenya. But the authors did not have permission from the center to use data from the women, nor the necessary ethics approval from Moi University to carry out the work.

Here’s the retraction note for “Effectiveness of option B highly active antiretroviral therapy (HAART) prevention of mother-to-child transmission (PMTCT) in pregnant HIV women:”

Continue reading Study on pregnant women with HIV lied about having ethics approval

Data manipulation flushes paper on gut bacteria

cell reportsData manipulation in a Cell Reports paper blew the importance of a kind of bacteria out of proportion.

Retracted this month — less than three months after it was published — the paper showed, according to a summary on the cover page:

B. subtilis is a symbiont that resides in the gut of C. elegans and generates nitric oxide that is essential for the host. Xiao et al. demonstrate that nitric oxide promotes defense against pathogenic bacteria by activating p38 MAPK, demonstrating the importance of commensal bacteria in host immunity.

But B. subtilis — a member of the Bacillaceae family — aren’t actually as plentiful as they appeared, explains the retraction notice for “Gut-Colonizing Bacteria Promote C. elegans Innate Immunity by Producing Nitric Oxide:”

Continue reading Data manipulation flushes paper on gut bacteria

Biologists earn 5th retraction following Swedish investigation

plos pathA team of biologists have earned a fifth retraction for a paper containing manipulated images, following an investigation by the Swedish government.

Last year, the investigation found that former Uppsala University doctoral student Apiruck Watthanasurorot had manipulated figures in five papers, four of which have already been retracted. Earlier this year, we reported that his supervisor, last author Kenneth Söderhäll, had requested PLOS Pathogens simply correct the fifth paper because independent groups have confirmed the findings. But according to the retraction notice for “Bacteria-Induced Dscam Isoforms of the Crustacean, Pacifastacus leniusculus,” Söderhäll has since agreed to the retraction:

Continue reading Biologists earn 5th retraction following Swedish investigation

Cancer paper that doctored image from Science story earns retraction

lungcancercoverHere’s a joke for all you middle-schoolers out there. How are doctored images like bad pennies? They keep cropping up!

Here’s the latest one we’ve picked up: Lung Cancer has retracted a 2014 paper on the genetics of tumors after concluding the authors cribbed a figure that had appeared in a 2005 feature story in Science.

The paper, “ß-elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome,” drew attention on PubPeer last September from a reader who noticed striking similarities between one of the images the authors used and a figure in the Science piece (subscription required). According to the PubPeer commenter: Continue reading Cancer paper that doctored image from Science story earns retraction

Macchiarini did not obtain necessary ethics approvals, says Swedish Research Council

lancetSurgeon Paolo Macchiarini did not apply for the necessary ethics approval to perform the pioneering transplants he’s known for, according to the Swedish Research Council.

Chief Legal Counsel Anna Hörnlund, who wrote a letter in this week’s The Lancet, says Macchiarini’s work needed to obtain ethical approval from one of six regional ethical review boards, as required by Swedish law — and neither Macchiarini nor his former employer, Karolinska Institutet, did so:

Continue reading Macchiarini did not obtain necessary ethics approvals, says Swedish Research Council