Category: clinical study retractions

Novartis Diovan scandal claims two more papers

diabetes careA complicated story involving Novartis’s valsartan (Diovan) has led to the retraction of two more papers, one cascading from the other.

Last September, The Lancet retracted the Jikei Heart Study after a slew of retractions of related work prompted an investigation of valsartan research. That investigation found evidence of data manipulation and the failure of one researcher to note his Novartis affiliation. The company has apologized.

Here’s one retraction, from Diabetes Care, for “The Shiga Microalbuminuria Reduction Trial (SMART) Group. Reduction of Microalbuminuria in Patients With Type 2 Diabetes: The Shiga Microalbuminuria Reduction Trial (SMART):”

Continue reading Novartis Diovan scandal claims two more papers

Bogus Western blots lead to retraction of cancer paper

ejpharmA group of Italian researchers has retracted their 2013 paper on colorectal cancer because one of the authors, they, say, was tinkering with the data.

The article, “PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines,” appeared in the European Journal of Pharmacology in August. The first author was Giuseppina Gangemi, of the University of Salerno.

The paper purported to find that:

Continue reading Bogus Western blots lead to retraction of cancer paper

Late resveratrol researcher Dipak Das up to 20 retractions

Das, via UConn
Das, via UConn

Dipak Das, the former University of Connecticut researcher found to have committed more than 100 counts of misconduct, and who passed away last year, has had another retraction appear.

Here’s the notice, for “Dynamic Action of Carotenoids in Cardioprotection and Maintenance of Cardiac Health,” from Molecules:

Continue reading Late resveratrol researcher Dipak Das up to 20 retractions

“The Chrysalis Effect: How Ugly Initial Results Metamorphosize Into Beautiful Articles”

jomThe headline of this post is the title of a fascinating new paper in the Journal of Management suggesting that if the road to publication is paved with good intentions, it may also be paved with bad scientific practice.

Ernest Hugh O’Boyle and colleagues tracked 142 management and applied psychology PhD theses to publication, and looked for various questionable research practices — they abbreviate those “QRPs” — such as deleting or adding data after hypothesis tests, selectively adding or deleting variables, and adding or deleting hypotheses themselves.

Their findings?

Continue reading “The Chrysalis Effect: How Ugly Initial Results Metamorphosize Into Beautiful Articles”

Psychiatric Times reinstates retracted essay on “satanic ritual abuse”

psych timesLast month, we brought readers the story of a retraction in December from Psychiatric Times, of an essay by Richard Noll that included this passage:

Despite the discomfort it brings, we owe it to the current generation of clinicians to remember that an elite minority within the American psychiatric profession played a small but ultimately decisive role in the cultural validation, and then reduction, of the Satanism moral panic between 1988 and 1994. Indeed, what can we all learn from American psychiatry’s involvement in the moral panic?

That essay was republished on March 19, along with an editor’s note:

Continue reading Psychiatric Times reinstates retracted essay on “satanic ritual abuse”

Controversial paper linking conspiracy ideation to climate change skepticism formally retracted

frontiersA year after being clumsily removed from the web following complaints, a controversial paper about “the possible role of conspiracist ideation in the rejection of science” is being retracted.

The paper, “Recursive fury: Conspiracist ideation in the blogosphere in response to research on conspiracist ideation,” was authored by Stephan Lewandowsky, John Cook, Klaus Oberauer, and Michael Marriott, and published in Frontiers in Psychology: Personality Science and Individual Differences.

Continue reading Controversial paper linking conspiracy ideation to climate change skepticism formally retracted

Alleged faked heart tests “might affect inclusion of data” in study led by UCSF

Parag Patel with Girl Scouts, Kenya, via FICCS
Parag Patel with Girl Scouts, Kenya, via FICCS

We have an update on the case of Parag Patel, the Park Ridge, Illinois cardiologist whom the Office of Research Integrity (ORI) said “engaged in research misconduct by directing or intimidating fellows and others to influence” test results so that patients would be eligible for a clinical trial.

A spokesperson for the clinical trial’s sponsor, the University of California, San Francisco (UCSF), tells us: Continue reading Alleged faked heart tests “might affect inclusion of data” in study led by UCSF

Final report in Smeesters case serves up seven retractions

smeestersErasmus University in Rotterdam has issued its final report on psychologist Dirk Smeesters, concluding that the former Erasmus faculty member had committed research misconduct in a total of seven papers. Three of those articles already have been retracted in the case, as we reported in December 2012.

The committee investigation is in fact a follow-up inquiry — thus its name, the Smeesters Follow-Up Investigation Committee — prompted by concerns that an initial probe was incomplete. According to the report, the four-member panel conducted an “in-depth analysis” of every paper Smeesters, who left the university’s Rotterdam School of Management in July 2012, was “actively” involved in. That turned out to be 22 articles (not including three others already retracted).

The final report is worth reading, presented here as a pdf. The four articles are: Continue reading Final report in Smeesters case serves up seven retractions

Researcher intimidated trainees into faking heart test results: ORI

Parag Patel with Girl Scouts, Kenya, via FICCS
Parag Patel with Girl Scouts, Kenya, via FICCS

A cardiology researcher in Illinois coerced trainees to fake the results of a heart test so that patients would qualify to enter a clinical trial, according to a new finding by the Office of Research Integrity (ORI).

Here’s an excerpt from the ORI’s notice about Parag V. Patel, of Advocate Lutheran General Hospital, in Park Ridge, Illinois: Continue reading Researcher intimidated trainees into faking heart test results: ORI

Why was that lung cancer paper retracted? The “authors’ reason,” of course

jthordisTwo researchers who wrote a review article on the genetics of lung cancer have retracted the paper. But why evidently is for them to know and us to find out.

The article, “Epigenetic aberrant methylation of tumor suppressor genes in small cell lung cancer,” was published in the August 2013 issue of the Journal of Thoracic Disease by authors from Shandong University in China.

According to the retraction notice: Continue reading Why was that lung cancer paper retracted? The “authors’ reason,” of course