Data fabrication by ex-Harvard researcher takes down paper on Huntington’s disease

A researcher at Harvard Medical School and Massachusetts General Hospital is retracting a paper due to “inappropriate manipulation and fabrication of data” by the first author.

According to the retraction notice, published Aug. 22, corresponding author Marian DiFiglia is retracting the paper because the alleged misconduct by the first author, Antonio Valencia:

led to an incorrect conclusion in the paper that NADPH activity is elevated in Huntington’s disease (HD). Some original data were missing and efforts to replicate findings using the reported method or an alternative approach were unsuccessful. An institutional faculty panel supports the decision and the reasons for the retraction.

The notice added that the alleged data manipulation and fabrication affected bar graphs in two of the paper’s figures.

Terri Ogan, a spokesperson for Mass General, told Retraction Watch that Valencia no longer works at the institution, but declined to say whether there has been an investigation into the alleged misconduct: Continue reading Data fabrication by ex-Harvard researcher takes down paper on Huntington’s disease

Authors retract Science paper after investigation reveals manipulated images

Researchers at a prominent Japanese university have retracted a 2015 paper in Science, after an investigation uncovered image falsification and fabrication.

Last September, the University of Tokyo began an investigation of seven papers from the lab of cell biologist Yoshinori Watanabe after receiving anonymous allegations. In May 2017, the university determined that five papers contained falsified or fabricated images, and announced the results of its investigation on August 1. Two of the papers were published in Science, two in Nature and one in EMBO Reports.

On July 1 2017, EMBO Reports issued an erratum to the 2011 paper flagged in the investigation, correcting issues in several figures. Here’s the retraction notice for “The inner centromere–shugoshin network prevents chromosomal instability,” the 2015 paper in Science and the first of the papers to be retracted: Continue reading Authors retract Science paper after investigation reveals manipulated images

Amid legal battle, psych journal issuing caution about torture paper

A psychology journal plans to issue an editor’s note about a controversial paper exploring what the author called “the biggest scandal to hit” the American Psychological Association (APA) in years.

The note cautions readers that the subject of the paper, published in the SAGE journal Teaching of Psychology, is part of a pending lawsuit, and that “teachers considering using the article in their classrooms” should watch for developments in the case.   Continue reading Amid legal battle, psych journal issuing caution about torture paper

“Scientifically misleading errors” prompt authors to withdraw paper

A group of authors have withdrawn a paper after revealing a litany of issues to the journal that published it. Among those issues were “scientifically misleading errors,” “insufficient” validation, and a disagreement between the researchers on whether it should have been published at all.

Optimal DNA structure of reverse-hairpin beacons for label-free and positive surface enhanced Raman scattering assays,” originally published in June in Optical Materials Express (OMEx), was retracted Aug. 7. The paper purported to describe a detection method for RNA associated with influenza virus. It has not yet been cited, according to Clarivate Analytics’ Web of Science.

Here’s the full list of issues cited in the retraction notice: Continue reading “Scientifically misleading errors” prompt authors to withdraw paper

Publisher flags paper on same-sex parenting after neo-Nazi group cites it

A publisher has issued an expression of concern (EoC) about a study that claimed children with same-sex parents were at greater risk of depression and abuse, after posters using statistics from the paper to support a homophobic message appeared in Australia and the US.

On Aug. 21, several news websites reported that these posters were appearing in Melbourne, Australia, citing claims from a 2016 paper published in Depression Research and Treatment, which said that children with same-sex parents are more at risk for depression, abuse, and obesity than children with opposite-sex parents. The poster had also appeared previously in Minneapolis and has been traced to a neo-Nazi group, as reported by HuffPost Australia. Australia is preparing for a national, non-binding, mail-in vote on whether to provide marriage equality for same-sex couples.

The EoC mechanism, which was chosen by the journal’s publisher, Hindawi, is an unusual choice here. The paper’s author, D. Paul Sullins, a sociology professor at The Catholic University of America and the paper’s author, told Retraction Watch that Hindawi contacted him Aug. 21 about the decision. Initially, he told us he didn’t have any “particular objection to it,” but later told us he changed his mind after he read more about COPE’s guidelines for EoCs: Continue reading Publisher flags paper on same-sex parenting after neo-Nazi group cites it

Updated: Ohio State revokes PhD of co-author of now-retracted paper on shooter video games

Jodi Whitaker, via University of Arizona

[This post, which at 1200 UTC 8/25/17 originally reported on the then-upcoming vote, has been updated at 1800 UTC 8/25/17 to include the results of the vote.]

A researcher who co-authored a paper about video games that was retracted earlier this year has had her PhD from The Ohio State University revoked.

As WOSU reported this afternoon, the vote today of the university’s Board of Trustees was unanimous. The scheduled vote on whether to revoke Jodi Whitaker’s degree was first reported yesterday by The Columbus Dispatch.

While a graduate student at Ohio State, Whitaker was co-author of a paper that claimed to find that first-person shooter video games improved marksmanship. As we’ve reported, the paper, published online in 2012, was retracted earlier this year, two years after a university committee was alerted to irregularities in the data by two outside researchers.

The controversy over the paper became heated at times. Continue reading Updated: Ohio State revokes PhD of co-author of now-retracted paper on shooter video games

Given “wrong pathology slides,” heart journal retracts paper

A cardiology journal has retracted a paper after the authors were unable to provide correct pathology slides to replace the wrong ones submitted with the original manuscript.

The paper is titled “Aortic Valve Endocarditis and Coronary Angiography With Cerebral Embolic Protection,” published on April 10, 2017 in The Journal of the American College of Cardiology: Cardiovascular Interventions (JACC:CI). It has not yet been cited, according to Clarivate Analytics’ Web of Science.

JACC:CI retracted the paper on Aug. 14, providing this notice: Continue reading Given “wrong pathology slides,” heart journal retracts paper

Hey, that’s my case study: Another retraction after doctors claim rights to case write-up

A group of researchers have retracted their 2016 case report about a rare dermatologic disorder in the wake of disputes about authorship and institutional approval.

The paper describes a young boy with Job’s Syndrome, in which patients experience painful, itchy and frequently disfiguring skin lesions, along with a constellation of other possible symptoms. The condition is extremely rare, occurring in less than one in 1 million births.

This isn’t the first time a journal has retracted a case study after another group of authors claimed ownership of the case. Earlier this year, we covered a retraction from a neuro-ophthalmology journal after the doctors who treated a patient suffering from a gruesome eye trauma took issue with the fact that radiologists had already published their diagnostic images as a case study.

According to the notice for this latest retraction:

Continue reading Hey, that’s my case study: Another retraction after doctors claim rights to case write-up

SAGE journal retracts three more papers after discovering faked reviews

SAGE recently retracted three 2015 papers from one of its journals after the publisher found the articles were accepted with faked peer reviews. The retraction notices call out the authors responsible for submitting the reviews.

This trio of retractions is the second batch of papers withdrawn by Technology in Cancer Research & Treatment over faked reviews in the past eight months. In 2016, the journal began investigating concerns from an anonymous tipster about faked reviewer reports and subsequently retracted three papers in December over “manipulation of the peer-review process” (1, 2, 3).

Jennifer Lovick, the journal’s executive editor, told us the recent issues have prompted the journal to take steps to strengthen the peer review process: Continue reading SAGE journal retracts three more papers after discovering faked reviews

Released FDA docs reveal details of agency’s (failed) attempt to retract paper

Earlier this year, a raging controversy regarding a new drug spilled into the pages of a leading medical journal: the head of the U.S. Food and Drug Administration and another official publicly called for the retraction or correction of a peer-reviewed article about the drug. They didn’t get their wish. Now, documents released by the FDA via a lawsuit shed light on the attempt — and show how tricky it can be to correct the official record.

The controversy surrounds the approval of eteplirsen, a drug approved last September to treat Duchenne Muscular Dystrophy, a rare but invariably fatal disease that strikes (mostly) young boys. Eteplirsen was approved over the objections of the FDA team that reviewed the drug, which determined that there was insufficient evidence to approve the drug.

But the controversy didn’t end within the walls of the FDA complex. Ellis Unger, who led the review team, believed that one of the principal studies of the drug, published in the Annals of Neurology, was “misleading” because it was based on “unreliable data.” So in early November, Unger, joined by the then-head of the FDA, Robert Califf, took the extremely rare move of writing to the editor of the journal to “urge that the paper be corrected or retracted….”

According to the documents, the authors of the Annals article did, in fact, agree to correct the article.

On November 9, 2016, Clifford Saper, Annals‘ editor in chief, wrote to Califf and Unger:

Continue reading Released FDA docs reveal details of agency’s (failed) attempt to retract paper