Category: by subject

Undisclosed conflicts of interest usually lead to corrections – but for some journals, that’s not enough

When authors are faced with filling out a journal’s conflict of interest form, deciding what qualifies as a relevant conflict can be tricky. When such omissions come to light, only rarely do they result in retractions – and certainly not author bans. But there are exceptions.

In October, the journal Chest retracted a 2015 review article exploring how mechanical ventilation can be used most effectively to manage acute respiratory distress syndrome (ARDS) after finding that the authors failed “to disclose all relevant conflicts of interest.” What’s more, the journal initially planned to ban the two authors with undisclosed conflicts from submitting papers to the journal for three years, but ultimately decided against it.

The Committee on Publication Ethics says that retractions may be warranted in cases of undisclosed conflicts of interest, but in our experience, most notices that cite that reason mention other problems with the paper, as well. Not this case – here, the only thing that seemed wrong with the paper was the authors’ failure to mention their ties to a ventilator company. The authors requested a correction – the usual fix, one accepted by the other journals they contacted – but to Chest, that wasn’t enough.

Here’s the retraction notice for “Mechanical Ventilation as a Therapeutic Tool to Reduce ARDS Incidence”: Continue reading Undisclosed conflicts of interest usually lead to corrections – but for some journals, that’s not enough

What turned a cancer researcher into a literature watchdog?

Jennifer Byrne

Sometime in the middle of 2015, Jennifer Byrne, professor of molecular oncology at the University of Sydney, began her journey from cancer researcher to a scientific literature sleuth, seeking out potentially problematic papers.

The first step was when she noticed several papers that contained a mistake in a DNA construct which, she believed, meant the papers were not testing the gene in question, associated with multiple cancer types.  She started a writing campaign to the journal editors and researchers, with mixed success. But less than two years later, two of the five papers she flagged have already been retracted.

When asked why she spent time away from bench research to examine this issue, Byrne told us:  Continue reading What turned a cancer researcher into a literature watchdog?

A Harvard whistleblower was subjected to a forced mental exam. Here’s why.

Last March, a PhD student at Harvard filed a misconduct allegation against his mentor, a prominent stem cell researcher. Three months later, he was taken from his home by police in the middle of the night for a forced psychiatric evaluation.

How did this happen? Continue reading A Harvard whistleblower was subjected to a forced mental exam. Here’s why.

At last, cancer reproducibility project releases some results — and they’re mixed

Nearly five years ago, researchers suggested that the vast majority of preclinical cancer research wouldn’t hold up to follow-up experiments, delaying much needed treatments for patients. In a series of articles publishing tomorrow morning, eLife has released the results of the first five attempts to replicate experiments in cancer biology — and the results are decidedly mixed.

As our co-founders Adam Marcus and Ivan Oransky write in STAT, the overall take-home message was that two studies generated findings similar to the original, one did not replicate the original, and two others were inconclusive.

They quote Brian Nosek, a psychologist at the University of Virginia, in Charlottesville, who runs the Center for Open Science, who has been leading the replication effort in his own field:

Continue reading At last, cancer reproducibility project releases some results — and they’re mixed

Breast cancer studies by fired Pfizer employee retracted

Last year, Pfizer fired one of its scientists following an investigation that ended with requests for retraction of five of her studies. Now, two of the five papers, which were first flagged on PubPeer, have been retracted.

One notice cites the Pfizer investigation, which found that cancer researcher Min-Jean Yin had included duplicated images in all five papers. Yin is the last author on both retracted papers.

Here’s the first notice from Clinical Cancer Research, which says most or all of the questioned images appear to be duplicates, and Pfizer — who sponsored the study and requested the retraction — can’t find the originals:
Continue reading Breast cancer studies by fired Pfizer employee retracted

“Crucial experiments” missing from retracted plant study

A 2016 study was retracted from a Frontiers journal after editors realized the authors had omitted experiments that didn’t support the hypothesis. 

Gearóid Ó Faoleán, ethics and integrity manager at Frontiers, which publishes Frontiers in Plant Science, told us:

In accordance with our complaints protocol, the Field Chief Editor led the investigation that resulted in the decision to retract the paper.

Here’s the retraction notice: Continue reading “Crucial experiments” missing from retracted plant study

Authors retract two statin papers, one with problems “too extensive to revise”

Researchers in China have retracted two 2016 papers about the possible use of a cholesterol-lowering agent to treat bleeding on the brain.

One of the retracted papers in the Journal of Neurosurgery (JNS) had multiple problems that were “too extensive to revise,” according to the lengthy retraction notice, relating to issues with authorship, data analyses, and patient enrollment. The notice is signed by first author Hua Liu of the Nanjing Medical University in China.

Liu is also the first author of another recently retracted paper in Frontiers in Neuroscience, pulled for incorrectly categorizing patients.

The JNS retraction notice begins: Continue reading Authors retract two statin papers, one with problems “too extensive to revise”

Journal retracts gastric cancer study with multiple duplications, authors MIA

An oncology journal has decided to retract a 2012 paper on gastric cancer after discovering duplicated data in multiple figures.

According to the retraction notice, the journal’s editorial board received a tip from a reader regarding the potential figure issues. Oncology Reports launched an investigation, which confirmed the allegations. The authors failed to respond to the journal’s multiple requests for more information.

Here’s the retraction notice: Continue reading Journal retracts gastric cancer study with multiple duplications, authors MIA

Authors retract tanning-UV radiation study for lacking approval

Researchers have agreed to pull a 2015 study exploring whether a plant extract can safeguard tanners from ultraviolet exposure after not obtaining formal approval from an ethics committee.

According to the first author, the problem lay in a misunderstanding – when they originally applied for approval six years ago, the researchers believed they didn’t need to go through a formal approval process, since the compound was commercially available without a prescription. Once they realized their mistake, they chose to retract the paper.

Here’s the retraction note for “Oral Polypodium leucomotos increases the anti-inflammatory and melanogenic responses of the skin to different modalities of sun exposures: a pilot study,” published in Photodermatology Photoimmunology & Photomedicine.  Continue reading Authors retract tanning-UV radiation study for lacking approval

Does social psychology really have a retraction problem?

Armin Günther

That’s the question posed by Armin Günther at the Leibniz Institute for Psychology Information in Germany in a recent presentation. There is some evidence to suggest that psychology overall has a problem — the number of retractions has increased four-fold since 1989, and some believe the literature is plagued with errors. Social psychologist Diederik Stapel is number three on our leaderboard, with 58 retractions.

But does any particular field have more retractions, on average, than others? Günther examines some trends and provides his thoughts on the state of the field. Take a look at his presentation (we recommend switching to full-screen view): Continue reading Does social psychology really have a retraction problem?