Category: clinical study retractions

Two groups mistakenly publish case reports on the same patient

Journal of Clinical Pharmacy and Therapeutics

Talk about a popular patient: A woman who developed a case of internal bleeding while taking the anticoagulant Xarelto (rivaroxaban) was written up in not one — but two — case reports. The trouble was, both groups didn’t realize what the other was doing, so the more recent article is now being retracted from the Journal of Clinical Pharmacy and Therapeutics.

The authors, a trio of doctors at Sakarya University in Turkey, described the case of a 75 year-old woman who came to the emergency room for fatigue and stomach pain after taking rivaroxaban for three days. A scan revealed a rectus sheath hematoma.

However, the case had already been published a few months earlier in the Indian Journal of Pharmacology by a separate group of doctors from Sakarya, along with authors from Yenikent State Hospital and Vakfikebir State Hospital.

Continue reading Two groups mistakenly publish case reports on the same patient

“Our manuscript unintentionally failed to meet academic and publication standards”

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Authors of a 2014 review paper about the use of “as needed” medications by people with mental health diagnoses are retracting it, but we’re scratching our heads as to why.

The retraction appears in “The experiences of mental health professionals’ and patients’ use of pro re nata (PRN) medication in acute adult mental health care settings: a systematic review protocol of qualitative evidence,” published by The JBI Database of Systematic Reviews and Implementation Reports.

From the abstract of the paper:

Pro re nata is a Latin phrase meaning “for an unforseen need or contingency”…The authors of the systematic review found that although the practice of using “as required” medication is common there is no good evidence of whether this is the best way of helping people to be less agitated when compared to being given a regular dose of medication.

We’re not entirely sure what went wrong here. This is the full contents of the note:

Continue reading “Our manuscript unintentionally failed to meet academic and publication standards”

Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Paolo Macchiarini
Paolo Macchiarini

Following an investigation, Karolinska Institutet has found that surgeon and visiting professor Paolo Macchiarini acted in some cases “without due care,” but that his behavior “does not qualify as scientific misconduct.”

Karolinska’s Vice Chancellor has also recommended that Macchiarini submit an unspecified number of corrections “to clarify and rectify the failings that the inquiry has brought to light.”

Macchiarini is most well-known for pioneering the creation of tracheas from cadavers and patients’ own stem cells. However, the glow of his success was diminished somewhat after four Karolinska surgeons filed a complaint, alleging Macchiarini had downplayed the risks of the procedure and not obtained proper consent, among other accusations.

An external review by Bengt Gerdin of Uppsala University concluded in May that Continue reading Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

A mess: PLOS mistakenly publishes rejected ADHD-herbicide paper, retracts it

logoPLOS One has retracted a paper that links the most commonly used herbicide to ADHD, after it was “published in error.”

According to the note, the paper was “editorially rejected following peer review and consultation with the Editorial Board,” but ended up going through the production process anyway.

When we contacted the authors, they filled us in with more details.

Continue reading A mess: PLOS mistakenly publishes rejected ADHD-herbicide paper, retracts it

Diederik Stapel ups count to 55 retractions

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Diederik Stapel

Dutch social psychologist and well-known fraudster Diederik Stapel is up to 55 retractions. He remains secure in his spot at #4 on our leaderboard.

The “fraudulent” Social Cognition article found, according to its abstract, that the more positively you perceive yourself, the less you need to compare yourself to other people. Conversely, negative thoughts were linked to more comparison to others. As an article in the New York Times points out, where Stapel’s faulty studies often succeeded is in telling us what we want to believe about the world.

Here’s the retraction note for the article:

Continue reading Diederik Stapel ups count to 55 retractions

Paper on narcissistic CEOs earns big correction

home_coverIt may not be much of a surprise that narcissistic CEOs of pharmaceutical companies will make bold choices, such as adopting radically new technology. That idea remains true, despite a lengthy correction to a paper that supports it.

The paper, “CEO Narcissism, Audience Engagement, and Organizational Adoption of Technological Discontinuities,” in Administrative Science Quarterly, found support for the following hypothesis:

Continue reading Paper on narcissistic CEOs earns big correction

Former Wake Forest grad student fudged data for drug study

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Brandi Blaylock

A former graduate student at Wake Forest School of Medicine “presented falsified and/or fabricated data” in a government-funded drug study, according to findings released by the U.S. Office of Research Integrity earlier today.

The report was released in the wake of an investigation conducted by the university and the ORI. Investigators found that although Brandi Blaylock recorded responses of a dozen laboratory monkeys after giving them anti-abuse drugs, she hadn’t given them the compounds “per protocol.”

Blaylock then presented the data at “two poster presentations, several laboratory meetings, and progress reports.”

Some of her research was supported by a grant from the National Institute of Drug Abuse, “Dopamine D2 Receptors In Primate Models of Cocaine Abuse,” which examined the effects of novel dopamine D3 receptor compounds on drug addiction on monkeys.

However, according to the report, Blaylock presented the falsified responses from a dozen monkeys: Continue reading Former Wake Forest grad student fudged data for drug study

“Goodbye…”?: Editor pulls farewell editorial after deeming it “inappropriate”

3We’ve unearthed a retraction of an editorial titled “Goodbye…”, pulled from Cognition, Technology & Work by its retiring editor after he decided it was “inappropriate.”

The original text is not online. The note in its place reads, in full:

This article has been retracted due to unintended publication.

The author of the editorial is psychologist Erik Hollnagel, based at the University of Southern Denmark, who left the journal after a decade. Interestingly, his own research includes studies of “When Things Go Wrong” (per the title of one of his book chapters), ranging from financial crises to the Fukushima disaster.

The error that led to this reaction seems tiny, in comparison. Hollnagel explains:

Continue reading “Goodbye…”?: Editor pulls farewell editorial after deeming it “inappropriate”

Judge dismisses defamation suit against diabetes journal

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

Mario Saad can’t catch a break — yesterday, a Massachusetts judge dismissed his defamation suit against the American Diabetes Association, publisher of Diabetes, which published an expression of concern regarding four of his papers in March.

The researcher has tried — and failed — to use the courts to remove the EoC.

In Saad’s latest attempt to employ legal action against the journal — arguing the EoC was defamatory — the United States District Court of Massachusetts was clear in its ruling (which you can view in its entirety here):

Continue reading Judge dismisses defamation suit against diabetes journal

Analysis of pilots with prostate cancer retracted for “inappropriate data”

Aerospace Medicine and Human PerformanceIn case any pilots out there are worrying about their risk of prostate cancer based on a recent meta-analysis that found they are at least twice as likely to develop the disease, they should relax — the paper has been retracted.

The reason: “including inappropriate data from two studies that should be ineligible.”

“The risk of prostate cancer in pilots: a meta-analysis” reviewed eight studies to determine whether airline pilots, who are regularly exposed to radiation and other occupational hazards, have a higher incidence of prostate cancer. However, it also included studies that reported on prostate cancer among all U.S. Armed Forces servicemen, not pilots.

The retraction notice was posted in May — only months after it was published in Aerospace Medicine and Human Performance in February. The notice included a letter to the editor outlining flaws in the meta-analysis and an apologetic response from first author, David Raslau at the Mayo Clinic.

Here’s the notice (appearing at the bottom of page 2):

Continue reading Analysis of pilots with prostate cancer retracted for “inappropriate data”