Category: clinical study retractions

“Strange. Very strange:” Retracted nutrition study reappears in new journal

In an unusual turn of events, a nutrition paper has come back to life a year after being pulled from its original publication.

After the paper was retracted from the journal Obesity, the authors revised it and republished it in another journal, Pediatric Obesity. Both journals are published by Wiley. The second version of the paper doesn’t mention the previous retraction. Indeed, the journal editor told us he didn’t know the paper had been retracted. Still, he stood by his decision to publish it.

The authors told us the paper was retracted after editors at Obesity raised concerns over the authors’ methodology. The authors revised the paper, adding some analysis and explanation of their methodological approach, and said the new version was accepted by peer reviewers before being published in Pediatric Obesity.

However, an outside expert who reviewed both papers for us said he thinks the authors didn’t change enough. According to Patrick McKnight, head of the Measurement, Research methodology, Evaluation, and Statistics group at George Mason University and a Statistical Advisory Board member of STATS.org:

Continue reading “Strange. Very strange:” Retracted nutrition study reappears in new journal

Patient misdiagnosed with rare neurological side effect in retracted case study

When two surgeons in Greece learned that a patient had developed a rare side effect following weight loss surgery, they were eager to publish the case.

After extensive testing, the patient was diagnosed with Wernicke’s encephalopathy—a neurological disorder caused by thiamine deficiency—following a sleeve gastrectomy procedure. As the authors note in the paper, they had seen only eight other cases following the procedure in the literature.

It turns out, theirs was not the ninth. After the patient unfortunately died, he was examined by a coroner, who ruled he did not, in fact, have Wernicke’s encephalopathy. So Dimitrios Manatakis and Nikolaos Georgopoulos, both based at Athens Naval and Veterans Hospital in Greece, have retracted their 2014 case study.

When the first learned of the patient, the authors wanted to alert the surgical community to the case, given the rarity of this side effect, Manatakis told us: Continue reading Patient misdiagnosed with rare neurological side effect in retracted case study

Macchiarini blames Karolinska for losing data as he retracts 2014 paper

Ask and ye shall receive: A journal has retracted a 2014 paper by Paolo Macchiarini, upon request from the Karolinska Institutet (KI).

The latest news is only one step in a long-running saga about former star surgeon Macchiarini, who was dismissed from KI last year. To read more, check out our timeline.

KI announced it was asking the journal to pull the paper late last year, after concluding that four authors — including Macchiarini — were guilty of scientific misconduct. The paper had already been flagged by the journal with an expression of concern, noting the data presented in the paper may not be “fully representative” of the experiments.

Today, the journal issued a retraction notice, saying the authors wanted to retract the paper. All of the authors who could be reached have agreed to the retraction, including Macchiarini.

Here’s more from the notice:

Continue reading Macchiarini blames Karolinska for losing data as he retracts 2014 paper

Nature paper adds non-reproducibility to its list of woes

Despite taking some serious hits, a 2006 letter in Nature isn’t going anywhere.

Years ago, a university committee determined that two figures in the letter had been falsified. The journal chose to correct the paper, rather than retract it — and then, the next year, published a correction of that correction due to “an error in the production process.” To round it out, in June of last year, Nature published a rebuttal from a separate research group, who had failed to replicate the letter’s results.

Still, the first author told us there are no plans to retract the paper, since the follow up experiments published in the corrections confirmed the paper’s conclusions.

Continue reading Nature paper adds non-reproducibility to its list of woes

Scientist who sued university earns two more retractions, bringing total to five

A scientist who sued his employer for millions of dollars has earned two more retractions, for papers that had already been flagged by the journal.

By our count, Rakesh Kumar now has five retractions and multiple corrections.

Kumar sued his employer, George Washington University, for $8 million, alleging emotional distress when they put him on leave from his position as department chair following a finding of misconduct. That suit was settled last year, for undisclosed terms.

The two newest retractions in the Journal of Biological Chemistry — which tagged the papers with Expressions of Concern last year — both state that, according to Kumar, the problematic figures were assembled by “specific co-authors” — unnamed — in his lab. Here’s the first notice:

Continue reading Scientist who sued university earns two more retractions, bringing total to five

Prominent NIH researcher up to a dozen retractions

Stanley Rapoport. Source: NIH

Neuroscientist Stanley Rapoport hasn’t had much luck with his co-authors.

Recently, we’ve reported on multiple retractions of papers co-authored by Rapoport after three different first authors were found to have committed misconduct. Now, the fallout from one of those cases had led to four more retractions, bringing Rapoport’s total to 12.

The latest batch of retractions stem from the actions of Jagadeesh Rao.

Here’s the first notice, issued by Psychopharmacology:

Continue reading Prominent NIH researcher up to a dozen retractions

Editors retract paper about anesthesia procedure after investigation uncovers data issues

The editors of an anesthesiology journal have retracted a paper about predicting how patients will respond to a procedure, after the results of an investigation cast doubt on the validity and originality of the work.

According to the retraction notice, the editors became concerned about the validity of the data and conducted an investigation, which found irregularities, “including misrepresentation of results.” Because the authors could not provide adequate evidence to assuage these concerns, the editors decided to retract the paper.

The paper — about which facial muscles best predict if a patient is ready to be intubated — had already been flagged on F1000: A few years ago, two anesthesiologists from Florida commented that they found the article “confusing,” and felt that the authors “did not prove their hypothesis.”

Here’s the retraction notice for “Comparison of four facial muscles, orbicularis oculi, corrugator supercilii, masseter or mylohyoid, as best predictor of good conditions for intubation: A randomised blinded trial,” published in the European Journal of Anaesthesiology in 2013 and cited once: Continue reading Editors retract paper about anesthesia procedure after investigation uncovers data issues

Negligence by stressed-out postdoc led to retraction of high-profile paper, supervisor says

The timing was tight, but Sergio Gonzalez had done it. Gonzalez, a postdoctoral researcher at the Institute for Neurosciences of Montpellier (INSERM) in France, had a paper accepted in a top journal by the end of 2015, just in time to apply for a small number of highly sought-after permanent research positions that open up in France each year.

If Gonzalez had missed the January deadline for this system of advancement, known as concours, he would have had to wait until the following cycle to apply.

Once his paper was accepted by the Journal of Clinical Investigation, Gonzalez could breathe a sigh of relief. He began being invited to interviews. But then, a comment showed up at PubPeer.

Continue reading Negligence by stressed-out postdoc led to retraction of high-profile paper, supervisor says

Headline-grabbing Science paper questioned by critics

When zoologists at the University of Oxford published findings in Science last year suggesting ducklings can learn to identify shapes and colors without training (unlike other animals), the news media was entranced.

However, critics of the study have published a pair of papers questioning the findings, saying the data likely stem from chance alone. Still, the critics told us they don’t believe the findings should be retracted.

If a duckling is shown an image, can it pick out another from a set that has the same shape or color?  Antone Martinho III and Alex Kacelnik say yes. In one experiment, 32 out of 47 ducklings preferred pairs of shapes they were originally shown. In the second experiment, 45 out of 66 ducklings preferred the original color. The findings caught the attention of many media outlets, including the New York Times, The Atlantic, and BuzzFeed.

Martinho told us:

Continue reading Headline-grabbing Science paper questioned by critics

Journal flags another paper by diabetes researcher who sued to stop retractions

It would seem that resorting to legal means to avoid editorial notices doesn’t always work.

We’re coming to that conclusion after seeing yet another notice for Mario Saad, based at the University of Campinas in São Paulo, Brazil. In this case, it’s an expression of concern from the Journal of Endocrinology, on a 2005 paper that lists Saad as the second-to-last author. According to the notice, the journal is concerned the paper contains spliced and duplicated images; although the authors offered to repeat the experiments, the journal considered that potential delay “unacceptable.”

Despite Saad’s legal efforts, he is now up to 11 retractions, along with multiple expressions of concern.

Here’s the full text of the notice (which is paywalled, tsk tsk):

Continue reading Journal flags another paper by diabetes researcher who sued to stop retractions