Category: clinical study retractions

“Hindsight’s a bitch:” Colleagues dissect painful retraction

Two blog posts are shining additional light on a recent retraction that included some unanswered questions — namely, the identity of the researcher who admitted to manipulating the results.

To recap: Psychological Science recently announced it was retracting a paper about the relationship between the words you use and your mood after a graduate student tampered with the results. But the sole author — William Hart, an assistant professor at the University of Alabama — was not responsible.

The post raised some questions — for instance, who was the graduate student, and if his or her work was so influential to a paper, why was he/she not listed as an author? Hart declined to identify the student, but two new blogs — including one by one of Hart’s collaborators at the University of Alabama — are providing more details.

Continue reading “Hindsight’s a bitch:” Colleagues dissect painful retraction

Author says he lied about approval for animal research

A researcher in South Korea has retracted a 2015 paper after telling the journal he falsified the institutional approval required to conduct the animal experiments.

In the article, the author explicitly says that the Animal Experiment Review Board of a university based in Seoul, South Korea approved the experiments, but according to the journal, “the author did not receive an approval by the board and he used a false approval number.”

Here’s the retraction notice for “The role of compensatory movements patterns in spontaneous recovery after stroke,” published in the Journal of Physical Therapy Science (JPTS) in September 2015 and retracted in December: Continue reading Author says he lied about approval for animal research

3rd retraction appears for fired Pfizer breast cancer researcher

Pfizer has retracted a paper by a former employee who was fired after the company discovered she had been doctoring data.

The retraction, in Molecular Cancer Research, is the third of five papers Pfizer asked to retract, after an investigation discovered they contained duplicated images. The papers have been discussed on PubPeer, which is also mentioned in the latest retraction notice.

As a result of the investigation, Pfizer terminated the employment of Min-Jean Yin, the last author on the newly retracted paper.

According to the notice, Yin and five of her co-authors agreed to the retraction:

Continue reading 3rd retraction appears for fired Pfizer breast cancer researcher

Unexplained abnormalities in stem cells prompt Columbia researchers to pull diabetes paper

Researchers at Columbia University have retracted a 2013 paper in The Journal of Clinical Investigation, after uncovering abnormalities in the stem cell lines that undermined the conclusions in the paper.

Last year, corresponding author Dieter Egli discovered he could not reproduce key data in the 2013 paper because almost all the cell lines first author Haiqing Hua used contained abnormalities, casting doubt on the overall findings. When Egli reached out to Hua for answers, Hua could not explain the abnormalities. As a result, Hua and Egli agreed the paper should be retracted.

Since some of the details of how the paper ended up relying on abnormal cells remain unclear, the university confirmed to us that it is investigating the matter.

Here’s the retraction notice for “iPSC-derived β cells model diabetes due to glucokinase deficiency,” cited 42 times: Continue reading Unexplained abnormalities in stem cells prompt Columbia researchers to pull diabetes paper

When you have 94 retractions, what’s two more?

Attention Joachim Boldt: The 1990s are calling, and they want their papers back.

The Annals of Thoracic Surgery has retracted two papers from the early 1990s on which Boldt was the first author – bringing the retraction tally for the disgraced German anesthesiologist to 96, by our count. Both articles were found to contain manipulated data.

The first paper, from 1990, was titled “Acute Preoperative Plasmapheresis and Established Blood Conservation Techniques,” and was written when Boldt was on the faculty at Justus-Liebig University, in Giessen.

According to the notice:

Continue reading When you have 94 retractions, what’s two more?

When does animal research become unnecessary and cruel? A paper’s methods give a biologist pause

Elies Bik

Microbiologist Elies Bik is well-known for applying a close eye to studies, and has spent years anonymously submitting reports on plagiarism and image duplication to journal editors. Last year, she published an analysis of work, with troubling results – that 1 in 25 biomedical papers contains inappropriate duplications in images. She’s never stopped reading papers closely, and recently flagged one on Twitter for concerns about its methodology. Although Bik is not against animal research, she said the treatments rats faced in the paper made her queasy – and didn’t seem justified. She explains her reasoning below.

Continue reading When does animal research become unnecessary and cruel? A paper’s methods give a biologist pause

Coauthor’s past misconduct prompts dep’t chair to retract Diabetes study

A department chair of a Swedish university asked to retract a 2010 study in Diabetes after none of the authors could explain image-related ambiguities.

The matter prompted particular attention because the paper’s first author, Pontus Almer Boström, had been found guilty of scientific misconduct by the University of Gothenburg in 2012, after Jan Borén noted some irregularities in data calculated by Boström. At that point, the research group combed the data to identify further issues arising from Boström’s work, and didn’t find any.

But last summer, when a user on PubPeer raised questions about some of the images in the 2010 paper, the matter was brought back into focus. According to Borén, they found “no evidence of scientific misconduct in this study.” But Boström had left the university in 2009 and could not be reached, the corresponding author had passed away, and the remaining co-authors hadn’t stayed in the field. So Borén decided it would be best to retract the study to avoid any “lingering questions.”

Here’s the retraction notice for “The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes,” in which Borén thanks “Peer 1″ on PubPeer for “detecting the ambiguities and bringing them to our attention:” Continue reading Coauthor’s past misconduct prompts dep’t chair to retract Diabetes study

Authors couldn’t find a patient to give consent for case report. Then the patient found the report.

When a group of authors decided to write up a curious case of a 35-year-old woman with a mysterious mass that took 11 years to be diagnosed, they tried repeatedly to contact the patient for her permission. When they couldn’t reach her, they published the paper anyway, removing any identifiable information.

But the report apparently included enough details for the patient to recognize herself — and when she read the paper, she asked the authors to retract it.

That’s the story according to the publisher of the 2016 case study, which recently retracted it with this notice:

Continue reading Authors couldn’t find a patient to give consent for case report. Then the patient found the report.

“I placed too much faith in underpowered studies:” Nobel Prize winner admits mistakes

Daniel Kahneman

Although it’s the right thing to do, it’s never easy to admit error — particularly when you’re an extremely high-profile scientist whose work is being dissected publicly. So while it’s not a retraction, we thought this was worth noting: A Nobel Prize-winning researcher has admitted on a blog that he relied on weak studies in a chapter of his bestselling book.

The blog — by Ulrich Schimmack, Moritz Heene, and Kamini Kesavan — critiqued the citations included in a book by Daniel Kahneman, a psychologist whose research has illuminated our understanding of how humans form judgments and make decisions and earned him half of the 2002 Nobel Prize in Economics.

According to the Schimmack et al blog, Continue reading “I placed too much faith in underpowered studies:” Nobel Prize winner admits mistakes

Paper quickly retracted after author used another group’s work

The author of a 2016 paper has agreed to retract it after an investigation revealed that most of the article came from another research group at the same university.

According to the notice, the author based the majority of his paper on results generated by other scientists without their permission.

Here’s the retraction notice for “Controlled synthesis of magnetic block copolymers for anti-microbial purpose,” published in the Journal of Applied Polymer Science in November and retracted in February: Continue reading Paper quickly retracted after author used another group’s work