Category: clinical study retractions

Two researchers guilty of misconduct, says university investigation

Suchitra Sumitran-Holgersson

A Swedish university has concluded that two professors studying tissue engineering are guilty of misconduct in two published papers, including a 2012 study in The Lancet.

The two researchers are  Suchitra Sumitran-Holgersson and Michael Olausson, both based at the University of Gothenburg. The university investigation — launched after several of Holgersson’s papers were questioned on PubPeer — has concluded that the researchers didn’t follow proper ethical procedures in the two papers.

Here’s a statement from a university spokesperson:

Continue reading Two researchers guilty of misconduct, says university investigation

Group whose findings support video game-violence link loses another paper

Last July, Joseph Hilgard, a postdoctoral fellow at the Annenberg Public Policy Center at the University of Pennsylvania, saw an article in Gifted Child Quarterly that made him do a double take. Hilgard, who is studying the effects of violent media on aggressive behavior, said the results of the 2016 paper “caused me some alarm.”

The research—led by corresponding author Brad J. Bushman, a professor of communication and psychology at The Ohio State University (OSU)—showed that gifted and non-gifted children’s verbal skills dropped substantially after watching 12 minutes of a violent cartoon. The violent program had a greater impact on the gifted children, temporarily eliminating the pre-video verbal edge they displayed over their non-gifted peers.

To Hilgard, the results suggested that violent media can actually impair learning and performance. But the effect size was huge — so big, Hilgard thought it had to be a mistake. This, plus other questions, prompted Hilgard to contact the authors and the journal. Unfortunately, once he got a look at the data — collected by a co-author in Turkey who became unreachable after the recent coup attempt — the questions didn’t go away. So the journal decided to retract the paper.

Bushman’s body of work has continually supported the idea that violent media increases aggressive behavior, including a controversial 2012 study “Boom, Headshot!” that was retracted earlier this year.

What first struck Hilgard as odd about the 2016 paper was how large the effect of the violent cartoon was: Continue reading Group whose findings support video game-violence link loses another paper

Author duplicated a figure in three papers; two get retracted

Two journals have retracted two papers by the same group within months of each other, after editors were independently tipped off that they contained duplicated figures representing different experiments.

The two papers were published by PLOS ONE and The Egyptian Journal of Biochemistry and Molecular Biology (EJBMB) in 2015 and 2014, respectively. According to the PLOS ONE paper’s corresponding author, last author Saad A. Noeman from Tanta University in Egypt used the same Figure 1 in both papers, along with another 2013 paper in EJBMB.

Corresponding author Yasser S. El-Sayed, head of the Department of Forensic Medicine and Toxicology at Damanhour University in Egypt, told us he learned of this issue after a reader brought the figure manipulation and duplication concerns to PLOS ONE’s attention.

El-Sayed said that he tried to figure out what had happened.

Continue reading Author duplicated a figure in three papers; two get retracted

“Strange. Very strange:” Retracted nutrition study reappears in new journal

In an unusual turn of events, a nutrition paper has come back to life a year after being pulled from its original publication.

After the paper was retracted from the journal Obesity, the authors revised it and republished it in another journal, Pediatric Obesity. Both journals are published by Wiley. The second version of the paper doesn’t mention the previous retraction. Indeed, the journal editor told us he didn’t know the paper had been retracted. Still, he stood by his decision to publish it.

The authors told us the paper was retracted after editors at Obesity raised concerns over the authors’ methodology. The authors revised the paper, adding some analysis and explanation of their methodological approach, and said the new version was accepted by peer reviewers before being published in Pediatric Obesity.

However, an outside expert who reviewed both papers for us said he thinks the authors didn’t change enough. According to Patrick McKnight, head of the Measurement, Research methodology, Evaluation, and Statistics group at George Mason University and a Statistical Advisory Board member of STATS.org:

Continue reading “Strange. Very strange:” Retracted nutrition study reappears in new journal

Patient misdiagnosed with rare neurological side effect in retracted case study

When two surgeons in Greece learned that a patient had developed a rare side effect following weight loss surgery, they were eager to publish the case.

After extensive testing, the patient was diagnosed with Wernicke’s encephalopathy—a neurological disorder caused by thiamine deficiency—following a sleeve gastrectomy procedure. As the authors note in the paper, they had seen only eight other cases following the procedure in the literature.

It turns out, theirs was not the ninth. After the patient unfortunately died, he was examined by a coroner, who ruled he did not, in fact, have Wernicke’s encephalopathy. So Dimitrios Manatakis and Nikolaos Georgopoulos, both based at Athens Naval and Veterans Hospital in Greece, have retracted their 2014 case study.

When the first learned of the patient, the authors wanted to alert the surgical community to the case, given the rarity of this side effect, Manatakis told us: Continue reading Patient misdiagnosed with rare neurological side effect in retracted case study

Macchiarini blames Karolinska for losing data as he retracts 2014 paper

Ask and ye shall receive: A journal has retracted a 2014 paper by Paolo Macchiarini, upon request from the Karolinska Institutet (KI).

The latest news is only one step in a long-running saga about former star surgeon Macchiarini, who was dismissed from KI last year. To read more, check out our timeline.

KI announced it was asking the journal to pull the paper late last year, after concluding that four authors — including Macchiarini — were guilty of scientific misconduct. The paper had already been flagged by the journal with an expression of concern, noting the data presented in the paper may not be “fully representative” of the experiments.

Today, the journal issued a retraction notice, saying the authors wanted to retract the paper. All of the authors who could be reached have agreed to the retraction, including Macchiarini.

Here’s more from the notice:

Continue reading Macchiarini blames Karolinska for losing data as he retracts 2014 paper

Nature paper adds non-reproducibility to its list of woes

Despite taking some serious hits, a 2006 letter in Nature isn’t going anywhere.

Years ago, a university committee determined that two figures in the letter had been falsified. The journal chose to correct the paper, rather than retract it — and then, the next year, published a correction of that correction due to “an error in the production process.” To round it out, in June of last year, Nature published a rebuttal from a separate research group, who had failed to replicate the letter’s results.

Still, the first author told us there are no plans to retract the paper, since the follow up experiments published in the corrections confirmed the paper’s conclusions.

Continue reading Nature paper adds non-reproducibility to its list of woes

Scientist who sued university earns two more retractions, bringing total to five

A scientist who sued his employer for millions of dollars has earned two more retractions, for papers that had already been flagged by the journal.

By our count, Rakesh Kumar now has five retractions and multiple corrections.

Kumar sued his employer, George Washington University, for $8 million, alleging emotional distress when they put him on leave from his position as department chair following a finding of misconduct. That suit was settled last year, for undisclosed terms.

The two newest retractions in the Journal of Biological Chemistry — which tagged the papers with Expressions of Concern last year — both state that, according to Kumar, the problematic figures were assembled by “specific co-authors” — unnamed — in his lab. Here’s the first notice:

Continue reading Scientist who sued university earns two more retractions, bringing total to five

Prominent NIH researcher up to a dozen retractions

Stanley Rapoport. Source: NIH

Neuroscientist Stanley Rapoport hasn’t had much luck with his co-authors.

Recently, we’ve reported on multiple retractions of papers co-authored by Rapoport after three different first authors were found to have committed misconduct. Now, the fallout from one of those cases had led to four more retractions, bringing Rapoport’s total to 12.

The latest batch of retractions stem from the actions of Jagadeesh Rao.

Here’s the first notice, issued by Psychopharmacology:

Continue reading Prominent NIH researcher up to a dozen retractions

Editors retract paper about anesthesia procedure after investigation uncovers data issues

The editors of an anesthesiology journal have retracted a paper about predicting how patients will respond to a procedure, after the results of an investigation cast doubt on the validity and originality of the work.

According to the retraction notice, the editors became concerned about the validity of the data and conducted an investigation, which found irregularities, “including misrepresentation of results.” Because the authors could not provide adequate evidence to assuage these concerns, the editors decided to retract the paper.

The paper — about which facial muscles best predict if a patient is ready to be intubated — had already been flagged on F1000: A few years ago, two anesthesiologists from Florida commented that they found the article “confusing,” and felt that the authors “did not prove their hypothesis.”

Here’s the retraction notice for “Comparison of four facial muscles, orbicularis oculi, corrugator supercilii, masseter or mylohyoid, as best predictor of good conditions for intubation: A randomised blinded trial,” published in the European Journal of Anaesthesiology in 2013 and cited once: Continue reading Editors retract paper about anesthesia procedure after investigation uncovers data issues