Category: clinical study retractions

Work by group at Australian university faces scrutiny

A journal is investigating research by a group in Australia, after receiving “serious allegations” regarding a 2017 paper about treating eye burns.

The journal, Frontiers in Pharmacology, has issued an expression of concern (EOC) for the 2017 paper while it investigates. The notice does not specify the nature of the allegations.  Meanwhile, several other papers by the three researchers, based at Deakin University in Geelong, Australia, have also come under scrutiny. Late last month, Frontiers in Pharmacology retracted a 2015 paper by Kislay Roy, Rupinder Kanwar, and Jagat R Kanwar, citing image duplication. A 2015 paper in Biomaterials received a correction in May 2017, again flagging image duplication.

Roy, the first author on the papers, is a postdoctoral research fellow; Rupinder Kanwar, a middle author, is a senior lecturer; and Jagat R Kanwar, the corresponding author on all three, is head of the Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research.

Gearóid Ó Faoleán, the ethics and integrity manager at Frontiers in Pharmacology, explained that the investigation into the flagged article is ongoing and the EOC “must serve as the extent of our public statement for the present.”

A spokesperson for Deakin University declined to comment on the allegations: Continue reading Work by group at Australian university faces scrutiny

Jumped the gun: Paper about non-finalized guidelines is retracted

Too soon? A surgeon is retracting his overview of new hernia surgery guidelines after it was published before the guidelines were finalized.

The paper, published in German in the journal, Der Chirurg, was also retracted because — according to two co-authors of the new guidelines — the final version of the guidelines was supposed to appear first, in English, in another journal.

The author of the paper, Dirk Weyhe, explained that the journal invited him to write an overview of the new guidelines for a special issue. According to Weyhe, a surgeon based in Germany who was a co-author on the guidelines, the aim of the special issue was to follow-up on an agreement reached at an international hernia conference in 2016: Continue reading Jumped the gun: Paper about non-finalized guidelines is retracted

“We do not want to create false hope”: Authors retract Cell paper they can’t replicate

A few years ago, researchers in Sweden had something to celebrate: They thought they had discovered a chink in the armor of the most common type of malignant brain cancer.

In a 2014 Cell paper, the team — led by Patrik Ernfors at the Karolinska Institutet — reported that they had identified a small molecule that could target and kill glioblastoma cells — the cancer that U.S. Senator John McCain was just diagnosed with — and prolong survival in mice with the disease. 

Satish Srinivas Kitambi, the paper’s first author, who is also based at the Karolinska Institutet, said the results got the team “really excited:” Continue reading “We do not want to create false hope”: Authors retract Cell paper they can’t replicate

NIH neuroscientist up to 19 retractions

Stanley Rapoport.
Source: NIH

The string of apparent bad luck continues for Stanley Rapoport.

Rapoport, a neuroscientist based at the U.S. National Institute on Aging, has lost three more papers in three journals due to the misconduct of his co-authors. By our count, these retractions bring his tally to 19 — and tie him for 21st place on our leaderboard.

The journals—Schizophrenia Research, Journal of Affective Disorders, and Biological Psychiatry— retracted the papers because the National Institutes of Health had found that one of Rapoport’s co-authors, Jagadeesh Rao, had “engaged in research misconduct by falsifying data.” Rao was corresponding author on all three papers.

According to a spokesperson for Elsevier, which publishes the journals, the Schizophrenia Research paper was retracted in July, the JAD paper in late May and the Biological Psychiatry paper in late April. The spokesperson told us that the publisher first received an email from the NIH about the misconduct findings on September 20, 2016, and that: Continue reading NIH neuroscientist up to 19 retractions

Diabetes researcher who sued to prevent retractions now has 13

A diabetes researcher who sued a publisher to protect several papers from being retracted recently received his 13th, in a prestigious gastroenterology journal.

Mario Saad, based at the University of Campinas in São Paulo, Brazil, has had a string of retractions over the past few years, including four in Diabetes after he lost a legal battle with the American Diabetes Association.

The latest retraction appears in Gastroenterology, citing possible image duplication. Saad is second-to-last author on the 2012 paper.

According to the retraction notice, the journal investigated data in several figures, and believes some were duplicated. The authors explained that the duplications resulted from inadvertently using wrong blots; still, the editors chose to retract the paper after determining they no longer had confidence in its conclusions.  

Here’s the retraction notice for “Obesity-Induced Increase in Tumor Necrosis Factor-α Leads to Development of Colon Cancer in Mice:” Continue reading Diabetes researcher who sued to prevent retractions now has 13

Volunteer researcher faked weeks’ worth of data

A volunteer researcher at Florida Atlantic University fabricated the results of mouse experiments over a 14-day period in June, 2016, according to a new finding issued by the U.S Office of Research Integrity (ORI).

According to the ORI, Alec Mirchandani made up the results of behavioral experiments to make it seem as if he had done the work, and falsified animal transfer logs, which affected research supported by the National Institute of Mental Health.

More specifically, the ORI determined that Mirchandani had “knowingly and intentionally:”

Continue reading Volunteer researcher faked weeks’ worth of data

Authors say patient threatened legal action after being subject of scholarly paper

A patient appears to have had a change of heart about being featured in a case report.

The patient cannot be identified in the paper published in Journal of Gastrointestinal and Liver Diseases. However, according to the retraction notice, she threatened to sue if the authors did not withdraw it. After receiving the threat, the paper’s corresponding author, Mariano Sica, told us that the authors immediately asked the journal to retract the paper.

We’ve written about similar cases where patients do not provide informed consent or withdraw it, but in this case we haven’t seen the threat ourselves.

We asked Sica if we could see the legal threat, and he said he couldn’t share it, explaining: Continue reading Authors say patient threatened legal action after being subject of scholarly paper

“We were devastated:” Authors retract paper after realizing they had used the wrong mice

Raymond Pasek and Maureen Gannon

Longtime readers of Retraction Watch may recall a 2011 post about a research team that retracted a paper after realizing that they had ordered the wrong mice. Maureen Gannon and Raymond Pasek of Vanderbilt University contacted us earlier this week to alert us to a similar case: Their retraction, earlier this month, of a 2016 paper from American Journal of Physiology – Endocrinology and Metabolism after discovering that “a colleague from another lab had mistakenly supplied us with the wrong transgenic mouse line.”

“We strongly believe that sharing this example will encourage other researchers to do the right thing when a mistake is discovered and promote academic integrity,” they wrote. So we asked them to answer a few questions about their experience with “Connective tissue growth factor is critical for proper β-cell function and pregnancy-induced β-cell hyperplasia in adult mice,” a paper that has been cited twice, according to Clarivate Analytics’ Web of Science. 

Retraction Watch: How, and when, did you become aware of the error? Continue reading “We were devastated:” Authors retract paper after realizing they had used the wrong mice

More notices appear for embattled Cornell food researcher

Journals have posted two corrections alongside papers by Brian Wansink, a food researcher whose work has lately come under fire.

One of the corrected papers was among the initial batch that raised eyebrows last year; after Wansink praised the productivity of one of his researchers, critics suggested four papers contained critical flaws. The questions about his work soon extended to other papers, one of which was retracted in April. That month, an internal review by Cornell University announced that Wansink made numerous mistakes, but did not commit misconduct. Wansink has pledged to reanalyze multiple papers.

One paper that was among those initially criticized has received a formal correction notice from the Journal of Product & Brand Management. The notice, which appears behind a paywall, has drawn fire from a regular critic of Wansink’s work, Jordan Anaya, who argues “this correction actually needs a correction, actually several.”

Here’s the notice for “Peak-end pizza: prices delay evaluations of quality:”

Continue reading More notices appear for embattled Cornell food researcher

Lancet retracts (and replaces) paper a year after authors report error that changes “all numbers”

In March 2016, researchers in Switzerland and Canada published a meta-analysis in The Lancet, exploring the optimal painkiller and dose for treating pain in knee and hip osteoarthritis. Soon after, the authors were informed of an error that would change “all numbers” in a paper that may influence clinical practice.

The authors contacted The Lancet immediately, in July 2016, to inform them of the issue. Sven Trelle, the paper’s corresponding author, also told us: Continue reading Lancet retracts (and replaces) paper a year after authors report error that changes “all numbers”