Category: biological psychiatry

Child took wrong compound for over a year after “communication error”

Credit: Steven Depolo, Flickr

A journal is retracting a paper after it discovered researchers gave a child the wrong supplement for more than a year.

Rhiannon Bugno, managing editor for Biological Psychiatry, told Retraction Watch the mix-up did not put the patient at risk. However, the mistake was enough for the journal’s editor, John Krystal, of Yale University, to request the retraction of a 2016 paper describing the young girl’s experience taking the compound,“Rett-like Severe Encephalopathy Caused by a De Novo GRIN2B Mutation Is Attenuated by D-serine Dietary Supplement.”

Originally published June 17, 2016, the paper was retracted Jan. 15. Led by corresponding author Xavier Altafaj, of the University of Barcelona (UB) and Bellvitge Biomedical Research Institute (IDIBELL), researchers described using an amino acid, D-serine, to treat a child with a rare genetic disorder that affects neurons.

According to the notice, the researchers did use D-serine in lab work used as proof-of-concept; however, when it came time to try it in the patient, as a result of a “communication error:”

Continue reading Child took wrong compound for over a year after “communication error”

NIH neuroscientist up to 19 retractions

Stanley Rapoport.
Source: NIH

The string of apparent bad luck continues for Stanley Rapoport.

Rapoport, a neuroscientist based at the U.S. National Institute on Aging, has lost three more papers in three journals due to the misconduct of his co-authors. By our count, these retractions bring his tally to 19 — and tie him for 21st place on our leaderboard.

The journals—Schizophrenia Research, Journal of Affective Disorders, and Biological Psychiatry— retracted the papers because the National Institutes of Health had found that one of Rapoport’s co-authors, Jagadeesh Rao, had “engaged in research misconduct by falsifying data.” Rao was corresponding author on all three papers.

According to a spokesperson for Elsevier, which publishes the journals, the Schizophrenia Research paper was retracted in July, the JAD paper in late May and the Biological Psychiatry paper in late April. The spokesperson told us that the publisher first received an email from the NIH about the misconduct findings on September 20, 2016, and that: Continue reading NIH neuroscientist up to 19 retractions

Researchers repeat retracted study, republish in same journal sans first author

biol psychWe’ve been following the case of Amine Bahi, a neuroscience researcher in the United Arab Emirates who has managed something unusual in the annals of Retraction Watch: Three different retractions for three completely different reasons. One was for “legal issues,” another was for lack of IRB approval, and the third was for using RNAs from the wrong species.

Now, Bahi’s co-authors have repeated the last of those studies with the right RNAs, and have republished their paper in the same journal, Biological Psychiatry — but without Bahi.

The retraction notice for “Blockade of Protein Phosphatase 2B Activity in the Amygdala Increases Anxiety- and Depression-Like Behaviors in Mice” now includes this final paragraph: Continue reading Researchers repeat retracted study, republish in same journal sans first author

Rats! Neuroscientist notches third retraction, this one for using the wrong RNAs

biol psychAmine Bahi, a neuroscience researcher in the United Arab Emirates, has had a third paper retracted.

Here’s the notice for “Blockade of Protein Phosphatase 2B Activity in the Amygdala Increases Anxiety- and Depression-Like Behaviors in Mice,” which was posted on November 19: Continue reading Rats! Neuroscientist notches third retraction, this one for using the wrong RNAs

Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”

jneuroscicoverThe Journal of Neuroscience has retracted a 2012 paper by a group from Sweden’s Karolinska Institutet for what appears to be research misconduct. But more on that in a moment.

The article, “The Existence of FGFR1-5-HT1A Receptor Heterocomplexes in Midbrain 5-HT Neurons of the Rat: Relevance for Neuroplasticity,” came from the lab of Kjell Fuxe, whose interests include Parkinson’s disease, addiction and depression. The first and second authors, Dasiel Oscar Borroto-Escuela and Wilber Romero-Fernandez, are listed as being post-docs in the lab.

According to the notice: Continue reading Journal of Neuroscience retracts plasticity paper for “substantial data misrepresentation”