Category: clinical study retractions

“A concerning – largely unrecognised – threat to patient safety:” Nursing reviews cite retracted trials

Richard Gray

Too many papers cite retracted research — even after it’s been retracted. It’s a problem. It can be especially a problem in clinical fields, where patient care is at stake. Recently, Richard Gray at La Trobe University in Australia and his colleagues examined the scope of the problem in the nursing field, noting how many systematic reviews included findings from retracted clinical trials. We spoke with Gray about their findings, published in the International Journal of Nursing Studies — and what they might mean for the safety of patients.

Retraction Watch: Retractions are a concern in any field, but as you note, when clinical practice is at stake, it can be particularly worrisome. Do you think your findings raise any potential concerns about patient safety?

Continue reading “A concerning – largely unrecognised – threat to patient safety:” Nursing reviews cite retracted trials

Caught Our Notice: Using this research tool? You’d better ask first

Via Wikimedia

Title: Patient Education After CABG: Are We Teaching the Wrong Information?

What Caught Our Attention: We’ve written about the controversy surrounding a commonly used tool to measure whether patients are sticking to their drug regimen, known as the Morisky Medication Adherence Scale (MMAS-8). It can cost thousands of dollars — and using it without payment/permission earns researchers a call from a collector, who has used legal threats to compel multiple teams to withdraw their papers (a phenomenon we wrote about in Science). The creator of the tool argues it’s copyrighted, and demanding fees ensures researchers use it properly, which avoids putting patients at risk. We’ve found a notice (paywalled, tsk-tsk) that reveals another group of authors used the tool without permission and, according to the notice, “incorrectly.”

Continue reading Caught Our Notice: Using this research tool? You’d better ask first

RAND re-releases withdrawn report modelling child mistreatment

A think tank has re-issued a report on child welfare in the U.S., six months after it pulled the document amidst criticism from dozens of researchers.

The report offered policy recommendations for improving the child welfare system, based on numerical modeling conducted by researchers at the RAND Corporation.

RAND pulled the initial version of the report in June, after researchers — including Richard Barth, dean of the University of Maryland’s school of social work and Emily Putnam-Hornstein, of the University of Southern California — criticized the model for underestimating the rate of maltreatment over a child’s lifetime.

The report, reissued Dec. 11, contains updates detailing how the RAND researchers addressed the criticism. However, Jeanne Ringel, a senior economist at RAND and the study’s lead author, told us: Continue reading RAND re-releases withdrawn report modelling child mistreatment

Caught Our Notice: Oops — 10-fold error reverses heart warning for Ghanaians

Via Wikimedia

Title: Ghanaians Might Be at Risk of Inadequate Dietary Intake of Potassium

What Caught Our Attention: Potassium-rich diets are thought to be “heart-healthy,” and after examining the average dietary habits of Ghanaian adults, researchers determined the average potassium (K) intake to be well below global standards.  However, the authors’ calculations of potassium intake per capita were too low by factor of 10, resulting in the incorrect conclusion that the average potassium intake was only 856 mg per day, an amount substantially lower than the World Health Organization (WHO) recommendation of 3510 mg/day.  The new calculations show an average K intake of 8,560 mg/day, well over the WHO guideline.  

We asked the corresponding author, David Oscar Yawson, about the source of the error, and he responded:

Continue reading Caught Our Notice: Oops — 10-fold error reverses heart warning for Ghanaians

Caught Our Notice: Columbia researcher up to five retractions

Via Wikimedia

Title: Endotoxaemia during left ventricular assist device insertion: relationship between risk factors and outcome

What Caught Our Attention: Robert J. Frumento first caught our notice in 2013, as a coauthor on a paper retracted with a nonspecific reference to author misconduct.  Three years later, Frumento was clearly identified as having fabricated data and a master’s degree, and added three retractions to his name. Now he’s got a fifth retraction, this one citing missing data and a lack of proof that data blinding was performed correctly.   Continue reading Caught Our Notice: Columbia researcher up to five retractions

University requests 4th retraction for psychologist under fire

Jens Förster

The University of Amsterdam has requested another retraction for a prominent social psychologist, after reviewing the dissertations he supervised while at the university.

The university made the announcement this week after reviewing the theses supervised by Jens Förster, whose own work has been subject to considerable scrutiny.

The results of this investigation come more than two years after an initial probe into Förster’s work, which found several of his papers likely contained unreliable data; three of these papers have been retracted and four have received expressions of concern. Förster, who recently left his position at Ruhr-Universität Bochum in Germany to start a private psychology practice, has always maintained that he did not manipulate his data. In 2015, he turned down a professorship, citing the toll the investigation had taken. Continue reading University requests 4th retraction for psychologist under fire

Psychologist under fire leaves university to start private practice

Jens Förster

Jens Förster, a prominent social psychologist whose work has been subject to much scrutiny, recently left his position at Ruhr-Universität Bochum in Germany to start a private psychology practice.

We’ve verified with the university that Förster no longer works there, but the circumstances of his exit are not entirely clear. 

Förster’s research has faced considerable scrutiny in the past few years. A 2015 report describing an investigation into Förster’s work concluded that several of his papers likely contained unreliable data. Three of those papers have been retracted and four others have received expressions of concern. Förster, however, has denied allegations that he manipulated his data. In 2015, he turned down a prestigious professorship, citing the personal toll the investigation had taken. Continue reading Psychologist under fire leaves university to start private practice

Caught Our Notice: How can a publication be a surprise to a corresponding author?

Via Wikimedia

Title: Umbelliferone reverses depression-like behavior in chronic unpredictable mild stress-induced mice via RIP140/NF-κB pathway

What Caught Our Attention: One would think that the corresponding author would have to be aware that they are submitting an article for publication — but apparently not, as this retraction demonstrates. The 2016 paper listed two corresponding authors — along with both of their emails and mailing addresses — but according to the retraction notice, one of them did not give consent “in any form” to the publication. Often, we see authors unaware of the use of their name when their email has been faked, but here, it’s possible the journal simply relied on the other corresponding author for all correspondence. Continue reading Caught Our Notice: How can a publication be a surprise to a corresponding author?

US court denies virus researcher’s latest appeal challenging 7-year funding ban

Scott Brodie has almost run out of options.

A former professor at the University of Washington, Brodie is currently involved in his third lawsuit challenging a finding of scientific misconduct and a seven-year funding ban handed down in 2010 by the U.S. Department of Health and Human Services’ Office of Research Integrity. He says that in the time since his case was heard by an administrative law judge at the ORI level, new evidence has come to light that shows he “did not have a ‘full and fair opportunity to litigate’ the issues.” His lawsuit sought a court order to have the ORI revisit its decision.

Last year, a U.S. District Court judge dismissed the case, saying it revisited old issues that had already been litigated, but Brodie appealed that decision. Now, his quest may have come to an end: On Nov. 27, the U.S. Court of Appeals for the D.C. Circuit dismissed the appeal. If he wants to continue the case, Brodie’s only remaining option is to appeal the decision to the U.S. Supreme Court.

In the court order, the panel of three judges wrote:

Continue reading US court denies virus researcher’s latest appeal challenging 7-year funding ban

Caught Our Notice: What if you find out a paper relied on expired herbal supplement?

Via Wikimedia

Title: Exploration of inhibitory mechanisms of curcumin in lung cancer metastasis using a miRNA- transcription factor-target gene network

What Caught Our Attention: The researchers were studying how curcumin, a component of the spice turmeric, can inhibit lung cancer metastases. But upon learning that the primary material had been expired at the time of testing (and realizing they were unable to repeat their experiments), the researchers pulled their paper. Expiration dates do have safety factors built in, but attention to such details is imperative in research.  Continue reading Caught Our Notice: What if you find out a paper relied on expired herbal supplement?