basic life sciences retractions – Page 50

Authors retract two papers for “severe conflicts of author sequences”

A group of authors has earned two retractions for a pair of papers on which they had “severe conflicts of author sequences,” according to the retraction note.

All of the authors were involved in a recent spate of compromised peer review that hit Springer journals back in August. Among the 64 retracted papers this summer, one included all of the authors on the two recently retracted papers, including first author Yan-Zhi Chen. Besides authorship issues, the latest two retractions also contain a “striking similarity to other publications,” according to the retraction notices.

The notes for the two papers are the same, except for the title of the paper. (They are also paywalled, tsk tsk!)

Here’s what the notes say:

Continue reading Authors retract two papers for “severe conflicts of author sequences”

Paper on plant immunity can’t fight off manipulation

A paper on how plants respond to bacteria has an invader of its own — data manipulation.

The “irregularities and inappropriate data manipulation” were found in a figure produced by the first author, Ching-Wei Chen, whose LinkedIn page lists him as a student at the National Taiwan University. The authors were unable to replicate the results in the figure, according to the note.

The authors are doing more experiments to verify the main conclusion of the 2014 paper, “The Arabidopsis Malectin-Like Leucine-Rich Repeat Receptor-Like Kinase IOS1 Associates with the Pattern Recognition Receptors FLS2 and EFR and Is Critical for Priming of Pattern-Triggered Immunity,” published in The Plant Cell.

The retraction note explains the what happened in more detail:

Continue reading Paper on plant immunity can’t fight off manipulation

Second of 3 retractions appears for biologist, the result of “a substantial number of falsifications”

A cell biologist who falsifed Western blots has notched a second retraction, with one more expected after a investigation at Nanyang Technological University in Singapore.

First author Sudarsanareddy Lokireddy, now apparently a research fellow at Harvard, did not agree to the retraction, the result of “a substantial number of falsifications.”

In December, we covered the results of the NTU investigation, where Lokireddy used to work. During that investigation, he admitted to falsifying data, Research Integrity Officer Tony Mayer told us. The end result: three retractions.

One of those papers was retracted by Cell Metabolism in December. The second paper, published in Molecular Endocrinology, has been cited 52 times, according to Thomson Scientific’s Web of Knowledge. The retraction note explains which figures were falsified:

Continue reading Second of 3 retractions appears for biologist, the result of “a substantial number of falsifications”

IVF embryo paper pulled for plagiarism, errors, lack of permissions

A journal is pulling an article (with approval of “most” of the authors) because a similar paper had already been published in Chinese.

That wasn’t the only problem with “Aneuploidy analysis of non-pronuclear embryos from IVF with use of array CGH: a case report,” published in the Journal of Molecular Histology.

The retraction note lists the three things that led to the paper’s retraction:

Continue reading IVF embryo paper pulled for plagiarism, errors, lack of permissions

Cancer Cell paper under investigation following anonymous queries on PubPeer

A Cancer Cell paper that caused a flurry of activity on the website PubPeer is under investigation, after the last author announced on the site that he’d requested a correction from the journal.

The 2012 paper sparked a lively dialogue last month on the post-publication discussion site, as commenters questioned Western blot images in which some bands appeared to be duplicates. The last author responded, noting he had alerted the journal to a “mishap,” and a correction would be forthcoming. However, some commenters remained unsatisfied, and questioned why the correction was taking so long to appear, as well as the explanation for what went wrong.

A spokesman from Cancer Cell confirmed to us the paper is under investigation:

Misidentified DNA leads authors to retract zebrafish cholesterol paper

Authors are retracting a 2012 paper on cholesterol metabolism in zebrafish after realizing it included a case of mistaken identity in a DNA sequence crucial to some aspects of the experiment.

A postdoc misidentified the plasmid in question after failing to fully sequence it before including it in the experiment. A technician in the lab found the mistake, last author Steven Farber, a researcher at the Carnegie Institution for Science in Maryland, explained:

When the omitted region was correctly sequenced we discovered it had an error.

He told us in a phone interview what that felt like:

We were like, holy crap.

Next came months of back and forth with the journal, discussing whether to correct or retract the paper. Farber tells us the mistake, which affects two figures,

was unfortunate. Most of the paper is in fact correct.

The paper, “Visualization of Lipid Metabolism in the Zebrafish Intestine Reveals a Relationship between NPC1L1-Mediated Cholesterol Uptake and Dietary Fatty Acid,” published in Chemistry & Biology, has been cited 21 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the detailed retraction note: Continue reading Misidentified DNA leads authors to retract zebrafish cholesterol paper

Suspicions of data manipulation lead to correction of testicular cancer paper

The corresponding author of a paper on testicular cancer is telling readers to discount a figure after she learned it may have been manipulated.

Although that one figure in the 2005 paper in the British Journal of Cancer may be problematic, the authors found data to support the other figures, and its conclusions.

This isn’t the first time first author Kerry Manton has faced questions over her data — in 2012, one of her papers was retracted following an investigation by her institution, the Queensland University of Technology. And in 2014, QUT repaid a $275,000 grant after finding Manton

failed to fulfill (her) responsibilities in relation to the responsible dissemination of research findings and that this, coupled with a failure to correct the errors, constituted research misconduct.

Here’s the corrigendum for “Hypermethylation of the 5′ CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis:”

Continue reading Suspicions of data manipulation lead to correction of testicular cancer paper

Retractions follow misconduct by biologist, one more on the way

Two journals have retracted papers by a biologist at the University of Tokyo who admitted to scientific misconduct, including data duplication and misrepresentation. Another journal is planning to retract one of the researcher’s papers later this month.

Hyun Kim studies a protein known as the “ski protein.” However, one analysis of the role of ski protein in development was retracted late last month by the Asian-Australasian Journal of Animal Sciences. The journal decided to investigate after Kim admitted to misconduct in two other papers published in a different journal.

Here’s the note for the paper:

Continue reading Retractions follow misconduct by biologist, one more on the way

Prostate cancer paper retracted after investigation can’t review original image

An article about how a COX-2 inhibitor (celecoxib) inhibits growth of prostate cancer in rats is being retracted after the authors were unable to provide an investigation committee at New York University with the backup they were asking for.

When the paper was published in 2003, first author Bhagavathi Narayanan worked at the Institute for Cancer Prevention in New York (also known as the American Health Foundation). But when the institute went broke the next year — thanks partly to lavish salaries and offices, as the New York Post reported — the authors claim they could no longer obtain back up for an image in the paper, once it was questioned years later by NYU, where Narayanan is now based.

Here’s the retraction note, published in Clinical Cancer Research:

Continue reading Prostate cancer paper retracted after investigation can’t review original image

Four retractions follow Swedish government findings of negligence, dishonesty

A Swedish ethical review board has censured two biologists and their employer, Uppsala University, for events related to “extensive image manipulations” in five papers published between 2010 and 2014. The case has led to criticism from an outside expert — who brought the allegations to Uppsala — over the current system in Sweden for handling such investigations.

Four of the papers have been retracted, and the authors have requested a correction in the fifth.

After an eight-month investigation, in September the government-run Expert Group for Scientific Misconduct at the Central Ethical Review Board in Stockholm, Sweden, concluded that Uppsala professor Kenneth Söderhäll — who has published more than 200 papers — and lecturer Irene Söderhäll acted “negligently” and “dishonestly” by Continue reading Four retractions follow Swedish government findings of negligence, dishonesty

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