Category: basic life sciences retractions

Antifungal drug paper didn’t have institution’s approval

Authors have pulled a paper on an antifungal drug that is potentially toxic because it lacked final approval from their institution.

The study describes a patient who had experienced liver toxicity after taking voriconazole. During the study, the authors re-administered the drug to the patient using “a slow dose titration.” But their institution didn’t approve the study before it was published online.

Here’s the retraction note for “Successful Rechallenge with Voriconazole following Medication-Induced Hepatotoxicity,” published in Antimicrobial Agents and Chemotherapy.  Continue reading Antifungal drug paper didn’t have institution’s approval

Duplicate publication uprooted from plant journal

AJPS2015012714522401The American Journal of Plant Sciences has retracted a duplicate publication — and is considerately describing what happened in a checklist that accompanies the retraction note.

The checklist is similar to one that friend of Retraction Watch Hervé Maisonneuve has proposed to the Committee on Publication Ethics.

The retracted paper shares one author with the paper that it duplicated from: Irfan Talib, whose affiliation is listed on the retracted paper as the University of Agriculture in Pakistan.

Here are the relevant fields on the checklist for “Study of Genetic Diversity in Germplasm of Upland Cotton (Gossypium hirsutum L.) in Pakistan” (a PDF on this page includes the checklist and the original paper):

Continue reading Duplicate publication uprooted from plant journal

Sperm paper impaired by “corporate company” analysis

2.coverWithout a certain protein, mouse sperm have motility disorders. That’s the conclusion of a paper that has itself been stopped — by errors in the data analysis, carried out by a third-party company.

The retraction note pins the analysis, which led to faulty data, on a “corporate company.” Aside from the companies that sell the kits used for substrates, assays, and detection, there’s only one company mentioned in the paper:

Generation of the mouse model was performed by the Cyagen Company (Guangzhou, China)

However, a representative of Cyagen says it does not offer the type of analysis described by the retraction note.

Here’s the full retraction note for the 2015 paper in Biology of Reproduction (which is paywalled — tsk, tsk):
Continue reading Sperm paper impaired by “corporate company” analysis

Fake email address — for author, not reviewer — fells another paper

Screen Shot 2016-02-22 at 10.19.43 AMWe’ve seen many cases of researchers creating fake email addresses to impersonate reviewers that usher their paper to publication.

But in the latest fake email incident, a journal is retracting a paper on liver cancer after the first author created a phony address for the last and corresponding author. Both are researchers at Zhengzhou University in China.

This isn’t the first time that an author has worked around the corresponding author: there’s a case from a few years ago in which the corresponding author didn’t know that the paper was being published at all. Recently, we also wrote about a doctor who was suspended in the UK after submitting papers without her co-authors’ knowledge, including creating a fake email for one of them.

This latest paper had another problem, too: plagiarism. Here’s the retraction note for “The influence of TLR4 agonist lipopolysaccharides on hepatocellular carcinoma cells and the feasibility of its application in treating liver cancer,” published in OncoTargets and Therapy:

Continue reading Fake email address — for author, not reviewer — fells another paper

Shigeaki Kato up to 38 retractions

Shigeaki Kato
Shigeaki Kato

Our retraction notice count for Shigeaki Kato, number seven on our leaderboard, has grown to 38.

The former University of Tokyo endocrinologist recently earned another retraction, for a paper in Archives of Biochemistry and Biophysics that contained image manipulation. As we’ve noted before, Kato resigned from the university in 2012 as it investigated his work for misconduct; in 2013 a Japanese newspaper reported that the investigation had found 43 papers from his lab contained “likely altered or forged materials.”

In addition to the new retraction, we’ve dug up four others for Kato from the past few years, plus one correction. Two of the retraction notices mention an investigation at the University of Tokyo.

First, the retraction note for “Multiple co-activator complexes support ligand-induced transactivation function of VDR,” published in December:

Continue reading Shigeaki Kato up to 38 retractions

NEJM corrects 3 papers after prominent cancer scientist left off credit for breakthrough

Screen Shot 2016-03-15 at 12.04.43 PMThe New England Journal of Medicine has corrected three highly cited papers to credit researchers who played a role in the work.

The papers describe a treatment in which engineered T cells fight leukemia, originally hailed as a “major advance” in the New York Times. Since the first paper appeared in 2011, co-author Carl June at the University of Pennsylvania has received more than $7 million in grants from the National Institutes of Health, according to MIT Technology Review. But according to a newly published correction, the three NEJM papers failed to note in the acknowledgement section that an important component of the experiments was supplied by researchers at St. Jude Children’s Research Hospital.

The correction, made 11 months after a request from co-author and Penn researcher David Porter, explains the contribution of the St Jude’s researchers:

Continue reading NEJM corrects 3 papers after prominent cancer scientist left off credit for breakthrough

Another paper by GM researcher pulled over manipulation concerns

Screen Shot 2016-03-14 at 11.52.18 AMA researcher who published findings questioning the safety of genetically modified organisms has lost a second paper following concerns of image manipulation.

Last week, the journal animal retracted a 2010 paper by Federico Infascelli, an animal nutrition researcher at the University of Naples, which claimed to find modified genes in the milk and blood of goats who were fed genetically modified soybeans. The retraction stems from an investigation that concluded the authors likely manipulated images, according to the note. Earlier this year, another journal retracted one of Infascelli’s papers that contained a duplicated figure.

In February, Italian paper La Repubblica (which we read with Google Translate) reported that the university found problems in three of his articles and issued a warning.

Here’s the retraction note for “Fate of transgenic DNA and evaluation of metabolic effects in goats fed genetically modified soybean and in their offsprings:”

Continue reading Another paper by GM researcher pulled over manipulation concerns

More retractions bring total to 7 for neuroscience pair, 2 more pending

JOCNAuthors have retracted two papers about visual perception and working memory from the Journal of Cognitive Neuroscience, after the first author admitted to falsifying or fabricating data in four other papers.

The authors have requested another two retractions, as well, which will bring the total for Edward Awh and his former graduate student David Anderson to nine retractions. (Earlier in 2015, they lost a paper due to an error in the analytic code, which Awh told us was unrelated to the misconduct.)

The retraction notice attached to both articles cites a 2015 settlement agreement between the Office of Research Integrity and first author Anderson (the “respondent”), who admitted to misconduct while working as a graduate student in the lab of Awh at the University of Oregon in Eugene. Since then, “additional problems” were discovered in the newly retracted articles, such as removed data points.

Awh, who has since moved to the University of Chicago, sent us a lengthy statement, explaining the concerns about each article: Continue reading More retractions bring total to 7 for neuroscience pair, 2 more pending

Authors retract striking circadian clock finding after failing to replicate

Screen Shot 2016-03-02 at 9.29.28 AMThe authors of a paper showing a “striking and unanticipated” relationship between light and temperature in regulating circadian rhythms are retracting it when the results couldn’t be replicated.

After being contacted by another group who couldn’t reproduce the data, the authors failed to, as well. They “have absolutely no explanation for the discrepancies with the original results,” according to the note in PLOS Biology.

It’s an unfortunate turn of events, but Continue reading Authors retract striking circadian clock finding after failing to replicate

Popular paper by famous longevity researcher gets mega-correction

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Leonard Guarente

A highly cited paper by a well-known scientist at the Massachusetts Institute of Technology who studies longevity could have aged better: The ten-year-old paper has earned its second correction.

It’s one of multiple papers by lead author Leonard Guarente that have been questioned on PubPeer. Guarente has already retracted one, and plans to address another. Continue reading Popular paper by famous longevity researcher gets mega-correction