Category: basic life sciences retractions

NIH neuroscientist up to 16 retractions

Stanley Rapoport. Source: NIH

Neuroscientist Stanley Rapoport just can’t catch a break.

Rapoport, who’s based at National Institute on Aging, is continuing to experience fallout from his research collaborations, after multiple co-authors have been found to have committed misconduct.

Most recently, Rapoport has had four papers retracted in three journals, citing falsified data in a range of figures. Although the notices do not specify how the data falsification occurred, Jagadeesh Rao, who was recently found guilty of research misconduct, is corresponding author on all four papers.

Back in December, Rapoport told us that a “number of retractions [for] Rao are still in the works:” Continue reading NIH neuroscientist up to 16 retractions

“Clumsy but genuine errors” prompt PNAS correction

Some accidental mistakes have led researchers to issue a long correction to a 2016 PNAS paper.

According to the notice, when the cell biology paper’s corresponding authors became aware of duplications in two images, they immediately notified the journal and the University of Nottingham. After examining the original data archives, the university found that the authors generated the correct images, but the person who prepared the figures selected the wrong images from the data archive.

According to John Atherton, faculty pro-vice-chancellor for the Faculty of Medicine and Health Sciences at the University of Nottingham in the UK, who oversaw the investigation: Continue reading “Clumsy but genuine errors” prompt PNAS correction

Drug researcher up to ten retractions

A pharmaceutical researcher has received his tenth retraction. The reason, once again: duplicating his previous work.

Giuseppe Derosa, based at the University of Pavia in Italy, lost a 2011 paper this month after journal editors identified “substantial duplication of an earlier published paper.” According to the notice, the authors failed to cite the previous work and to disclose that the manuscript had been published or was under consideration elsewhere.

Derosa has a habit of reusing clinical trial data in multiple papers. He received his first four retractions in 2015 for publishing the same clinical trial results six times—two of those papers were retracted over the summer and two more several months later. By 2016, a fifth from the bunch was retracted (one of the six still stands). Derosa received another retraction, citing duplication (which we covered here and which was not related to the six clinical trials).

Continue reading Drug researcher up to ten retractions

“There is an injustice in this article”

The editors of a plant biology journal have retracted a 2007 paper because of “an injustice.”

According to the notice, the editors of Cytologia found evidence of “apparent figure manipulation,” and decided to retract the paper.

This marks the 10th retraction for plant biologist Dibyendu Talukdar.

Talukdar, who is first and corresponding author on the 2007 paper and listed at the University of Calcutta in West Bengal, India, received his first retraction last July, which also cited suspected figure manipulation. Earlier this year, Talukdar received eight more retractions in seven different journals, all describing concerns over potential image duplication and manipulation.

Here’s the most recent retraction notice in Cytologia: Continue reading “There is an injustice in this article”

Paper with duplicated image “sequentially builds” on neuroscience work, authors argue

A neurochemistry journal has retracted a paper from a group in China over a duplicated image.

According to the notice, the authors used the same image in the two papers to represent different experimental conditions. The only distinguishing feature between the images: “apparent brightness changes.”

The authors defended their actions, explaining that the research published in Journal of Neurochemistry “sequentially builds” on their previous study in Journal of Neuroinflammation, which they mention in the 2015 paper’s discussion. In the notice, the authors were quoted saying:  Continue reading Paper with duplicated image “sequentially builds” on neuroscience work, authors argue

Would-be Johns Hopkins whistleblower loses appeal in case involving Nature retraction

A former researcher at Johns Hopkins who voiced concerns about a now-retracted paper in Nature has lost another bid for whistleblower protection.

Daniel Yuan, a longtime statistician for former Hopkins yeast geneticist Jef Boeke, was dismissed in 2011, after he’d spent years raising concerns about research coming out of the lab. Yuan’s criticisms, which continued after he stopped working for Boeke, peaked in 2012 after Boeke and former labmate Yu-li Lin published a paper in Nature. Later that year, Lin was found dead in his lab, a suspected suicide. In 2013, the paper was retracted, citing an inability to reproduce the main conclusions. 

Since 2013, Yuan has pursued a wrongful termination lawsuit, claiming that federal regulations surrounding scientific misconduct afforded him protection from retaliation.

In late March, Maryland’s highest court ruled against Yuan, saying that those misconduct regulations are “too vague” to offer cover to employees claiming whistleblower protection. According to lawyers we consulted, the decision could make it harder for would-be whistleblowers to fight retaliation, while also giving institutions more leeway to handle these issues on their own.

Continue reading Would-be Johns Hopkins whistleblower loses appeal in case involving Nature retraction

Journal retracts paper eight months after U.S. Feds announce findings of misconduct

In August, the U.S. Office of Research Integrity announced that a former postdoctoral fellow at the National Human Genome Research Institute (NHGRI) doctored data in two published papers.

It took one journal a little longer than five months to remove the researcher’s name from the co-author list, and replace one figure.

It took the second journal more than eight months to retract the paper.

Here’s the notice for “A BLOC-1 Mutation Screen Reveals that PLDN Is Mutated in Hermansky-Pudlak Syndrome Type 9,” published by the American Journal of Human Genetics (AJHG):

Continue reading Journal retracts paper eight months after U.S. Feds announce findings of misconduct

Paper by Harvard cancer biologist flagged over “credible concerns”

A cancer biologist at Harvard who’s issued multiple editorial notices in recent years has received an expression of concern about a 2011 paper, citing “credible concerns” with the data and conclusions.

The publisher does not detail the nature of the issues in the notice.

In the past few years, last author Sam W. Lee lost a Molecular Cell paper in 2013 due to figure duplication and a Journal of Biological Chemistry paper in 2015, citing “manipulated” data in a figure.

Lee also issued two mega-corrections in 2011 in Nature and Current Biology, which also cited figure duplication. Interestingly, both papers were corrected for a second time — the 2006 Current Biology paper in 2016, over figure-related errors, and the 2011 Nature paper in 2015, over concerns the animals used may have experienced excess suffering (prompting an editorial from the journal).

The latest notice, issued by the Journal of Biological Chemistry, doesn’t provide much information for the basis of its expression of concern over Lee’s 2011 paper: Continue reading Paper by Harvard cancer biologist flagged over “credible concerns”

Former UCLA vice-chancellor loses cancer paper for image manipulation

The former vice chancellor for research at the University of California, Los Angeles, has retracted a 2012 paper after an internal investigation found evidence of image manipulation.

The journal Molecular Cancer Therapeutics received a letter about the problems with the paper from the UCLA Research Integrity Officer, and a retraction request from last author James Economou, also the chief of surgical oncology.

According to the notice, the paper duplicated images from a 2011 paper also by first author Ali Jazirehi, based at UCLA. This is Jazirehi’s second retraction.

Here’s more from the notice:

Continue reading Former UCLA vice-chancellor loses cancer paper for image manipulation

Updated: Vaccine-autism study retracted — again

For the second time, a journal has quickly retracted a study that suggested vaccines raise the risk of autism and other neurodevelopmental disorders.

The study first raised a furor last year, prompting a Frontiers journal to quickly retract it. After it was republished in the Journal of Translational Science this month, that journal has also retracted it.

Although the titles of the two papers changed, the abstracts were nearly identical. Both studies surveyed the parents of 666 home-schooled children, 39% of whom where not vaccinated, and concluded that vaccination increased the risk of neurodevelopmental problems, particularly if children were born prematurely.

A representative of the Journal of Translational Science told us “Pilot comparative study on the health of vaccinated and unvaccinated 6- to 12-year-old U.S. children” has been retracted, and it will update us with an explanation.

Here’s more from the (now-retracted) abstract:

Continue reading Updated: Vaccine-autism study retracted — again