Category: image manipulation

One in 25 papers contains inappropriately duplicated images, screen finds

Elies Bik
Elies Bik

Elisabeth Bik, a microbiologist at Stanford, has for years been a behind-the-scenes force in scientific integrity, anonymously submitting reports on plagiarism and image duplication to journal editors. Now, she’s ready to come out of the shadows.

With the help of two editors at microbiology journals, she has conducted a massive study looking for image duplication and manipulation in 20,621 published papers. Bik and co-authors Arturo Casadevall and Ferric Fang (a board member of our parent organization) found 782 instances of inappropriate image duplication, including 196 published papers containing “duplicated figures with alteration.” The study is being released as a pre-print on bioArxiv.

An example the paper uses of “duplication with alteration” is this Western blot where a band has been duplicated: Continue reading One in 25 papers contains inappropriately duplicated images, screen finds

Cancer researcher earns 3 more retractions following NIH misconduct investigation

A researcher formerly based at the National Cancer Institute has earned three new retractions following an investigation that found she committed misconduct.

In May of last year, Stephanie Watkins, who now works at Loyola Medicine, earned one two retraction, which mentions a review by an investigation committee at the National Institutes of Health. Two of the new notes, published in Cancer Research, mention the review as well, and cite data falsification in a figure as the reason for retraction. Watkins is the only author that did not agree to those retractions.

There may be more changes to the literature — an editor at another cancer journal told us the journal is awaiting a decision from the Office of Research Integrity before deciding what to do with a paper by Watkins, given that she does not agree with the misconduct charges.

We’ll start with a retraction note from Cancer Research:

Continue reading Cancer researcher earns 3 more retractions following NIH misconduct investigation

Image splicing, duplications, inversions kill paper for well-known longevity researcher and alum of lab

Gizem Domnez
Gizem Donmez

A well-known scientist at the Massachusetts Institute of Technology who studies longevity has retracted a paper for “numerous examples of unindicated splicing of gel lanes,” as well as other problems.

This is Leonard Guarente‘s second retraction. He shares both with Gizem Donmez, an alum of his lab who now has three retractions. Donmez left her post as a Tufts professor in 2014.

Guarente told us in March — when we reported that he’d published a mega-correction on another paper — that he had planned to address issues with the paper, “SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones,” published in the The Journal of Neuroscience. Now, a retraction note has appeared “at the request of the authors.” It explains:

Continue reading Image splicing, duplications, inversions kill paper for well-known longevity researcher and alum of lab

Does this scientific image look familiar? It’s from a catalog

cover (4)There’s something strange about a 2008 paper on the role of nicotine receptors in promoting lung cancer: One of the western blot analyses looks like a version of an image from a commercial catalog.

A commenter on PubPeer pointed out the similarities between an image in “Role of α7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation,” which was published in Cell Proliferation, and one used to promote an enzyme sold by Cell Signaling Technology.

Unfortunately, if the images are indeed the same, we can’t tell for certain who copied from whom. But a representative of the company told us it generates its own images, and this one was likely created before the paper was published. The last author — for whom we’ve found three other retractions — denied that the paper copied the image.

Here’s the panel from the paper, which was published in 2008: Continue reading Does this scientific image look familiar? It’s from a catalog

Authors pull 14-year-old paper from PNAS over concerns of fabrication

13.coverAuthors have retracted a 2002 paper from PNAS because part of a figure “may have been fabricated,” and they no longer have the original data to prove otherwise.

The paper in question, “Deficient Smad7 expression: A putative molecular defect in scleroderma,” studied the signaling pathways that may underlie the autoimmune disease. It has been cited 198 times, according to Thomson Reuters Web of Science.

The authors, led by Pascal J Goldschmidt-Clermont, currently the Dean of the School of  Medicine at the University of Miami, have issued a retraction note, which appeared online yesterday: Continue reading Authors pull 14-year-old paper from PNAS over concerns of fabrication

Concerns about image manipulation? Sorry, the data were lost in a flood

1 (1)Lost your data? Blame nature.

Microchimica Acta has retracted a paper about water-soluble quantum dots after the authors couldn’t provide back-up for a figure that contained signs of manipulation. The reason, the editor told us: The corresponding author said the raw data were lost in a flood in Sri Lanka.

The journal asked the authors for the data after an investigation suggested that the paper included copied pictures of the same nanoparticle. The paper is one of four by the pair of co-authors flagged on PubPeer for potential image duplication.

Here’s the retraction note for “CdS/ZnS core-shell quantum dots capped with mercaptoacetic acid as fluorescent probes for Hg(II) ions:”

Continue reading Concerns about image manipulation? Sorry, the data were lost in a flood

Lawsuit couldn’t stop four retractions for diabetes researcher

Mario Saad
Mario Saad

Four expressions of concern in the journal Diabetes have turned into retractions for Mario Saad, a move which he had tried to stop with a lawsuit.

Last August, a judge dismissed Saad’s suit against the American Diabetes Association, which publishes Diabetes, concluding that the expressions of concerns on the papers were not defamation, but part of an “ongoing scientific discourse.” Now, after an investigation at the University of Campinas in Brazil, where Saad is based, and an assessment from an ADA ethics panel (which overturned some of Unicamp’s recommendations), the journal has added to that discourse by turning the EOCs into retractions — and flagging two more of Saad’s papers with EOCs.

Together, the retracted papers have been cited more than 600 times.

As the retraction notes explain, Continue reading Lawsuit couldn’t stop four retractions for diabetes researcher

Biologist’s research under investigation in Sweden after being questioned on PubPeer

Holgersson
Suchitra Sumitran-Holgersson

The University of Gothenburg in Sweden is investigating several papers co-authored by biologist Suchitra Sumitran-Holgersson after they were challenged on PubPeer.

Sumitran-Holgersson already has one retraction under her belt — of a 2005 Blood paper, after another investigation concluded the results “cannot be considered reliable.” Sumitran-Holgersson and her husband, co-author Jan Holgersson, did not sign the retraction notice. Both were based at the Karolinska Institutet (KI) at the time, but have since moved to the University of Gothenburg.

Now, the University of Gothenburg has launched its own investigation of the papers questioned on PubPeer, according to Continue reading Biologist’s research under investigation in Sweden after being questioned on PubPeer

Another paper by GM researcher pulled over manipulation concerns

Screen Shot 2016-03-14 at 11.52.18 AMA researcher who published findings questioning the safety of genetically modified organisms has lost a second paper following concerns of image manipulation.

Last week, the journal animal retracted a 2010 paper by Federico Infascelli, an animal nutrition researcher at the University of Naples, which claimed to find modified genes in the milk and blood of goats who were fed genetically modified soybeans. The retraction stems from an investigation that concluded the authors likely manipulated images, according to the note. Earlier this year, another journal retracted one of Infascelli’s papers that contained a duplicated figure.

In February, Italian paper La Repubblica (which we read with Google Translate) reported that the university found problems in three of his articles and issued a warning.

Here’s the retraction note for “Fate of transgenic DNA and evaluation of metabolic effects in goats fed genetically modified soybean and in their offsprings:”

Continue reading Another paper by GM researcher pulled over manipulation concerns

Popular paper by famous longevity researcher gets mega-correction

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Leonard Guarente

A highly cited paper by a well-known scientist at the Massachusetts Institute of Technology who studies longevity could have aged better: The ten-year-old paper has earned its second correction.

It’s one of multiple papers by lead author Leonard Guarente that have been questioned on PubPeer. Guarente has already retracted one, and plans to address another. Continue reading Popular paper by famous longevity researcher gets mega-correction