Category: data issues

Neuro journal pulls article for data theft, prompts misconduct probe

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Neuroscientists have retracted a research letter less than two months after it appeared, admitting they appeared to pass off others’ data as their own.

Two of the researchers are listed as affiliated with the University of California, San Francisco (UCSF), and the incident has led to a misconduct investigation at the institution, a UCSF spokesperson told us.

The article, “DNAJC6 variants in Parkinson’s disease and amyotrophic lateral sclerosis,” appeared in April. It was quickly followed by this notice, dated in May: Continue reading Neuro journal pulls article for data theft, prompts misconduct probe

Cancer researchers: We took data from another lab

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Authors have admitted to using material from another lab for their paper on neuroblastoma.

A spokesperson for Springer told us that the theft came to light when:

The scientists, from whom the data originated, contacted the journal.

The editor in chief of the journal investigated the case, the spokesperson told us, and then issued this retraction notice:

Continue reading Cancer researchers: We took data from another lab

How should journals update papers when new findings come out?

NEJM Logo

When authors get new data that revise a previous report, what should they do?

In the case of a 2015 lung cancer drug study in the New England Journal of Medicine (NEJM), the journal published a letter to the editor with the updated findings.

Shortly after the paper was published, a pharmaceutical company released new data showing the drug wasn’t quite as effective as it had seemed. Once the authors included the new data in their analysis, they adjusted their original response rate of 59%  — hailed as one of a few “encouraging results” in an NEJM editorial at the time of publication — to 45%, as they write in the letter. One of the authors told us they published the 2015 paper using less “mature” data because the drug’s benefits appeared so promising, raising questions about when to publish “exciting but still evolving data.”

It’s not a correction, as the original paper has not been changed; it doesn’t even contain a flag that it’s been updated. But among the online letters about the paper is one from the authors, “Update to Rociletinib Data with the RECIST Confirmed Response Rate,” which provides the new data and backstory:

Continue reading How should journals update papers when new findings come out?

Structural biology corrections highlight best of the scientific process

Nature_latest-coverIf you need evidence of the value of transparency in science, check out a pair of recent corrections in the structural biology literature.

This past August, researchers led by Qiu-Xing Jiang at the University of Texas Southwestern Medical Center corrected their study, first published in February 2014 in eLife, of prion-like protein aggregates called MAVS filaments, to which they had ascribed the incorrect “helical symmetry.” In March, Richard Blumberg of Harvard Medical School, and colleagues corrected their 2014 Nature study of a protein complex called CEACAM1/TIM-3, whose structure they had attempted to solve using x-ray crystallography.

In both cases, external researchers were able to download and reanalyze the authors’ own data from public data repositories, making it quickly apparent what had gone wrong and how it needed to be fixed — highlighting the very best of a scientific process that is supposed to be self-correcting and collaborative. Continue reading Structural biology corrections highlight best of the scientific process

Retractions aren’t enough: Why science has bigger problems

Andrew Gelman
Andrew Gelman

Scientific fraud isn’t what keeps Andrew Gelman, a professor of statistics at Columbia University in New York, up at night. Rather, it’s the sheer number of unreliable studies — uncorrected, unretracted — that have littered the literature. He tells us more, below.

Whatever the vast majority of retractions are, they’re a tiny fraction of the number of papers that are just wrong — by which I mean they present no good empirical evidence for their claims.

I’ve personally had to correct two of my published articles.   Continue reading Retractions aren’t enough: Why science has bigger problems

Journal pulls parasite paper over potential for patient harm

Parasitology ResearchA journal has retracted a paper about a molecular diagnosis for leishmaniasis out of concern it could lead to incorrect clinical diagnoses. 

According to Parasitology Research, all data behind the figures in the main manuscript and supporting information are correct, but the authors’ misinterpretation of the data could lead doctors to diagnose patients incorrectly. 

Let’s take a look at the retraction notice, which tells us a bit more about the nature of the problem: Continue reading Journal pulls parasite paper over potential for patient harm

Duke researcher adds another retraction in JCI, bringing count to 15

JCIWe’ve found another retraction for Erin Potts-Kant, a former researcher at Duke, bringing her total to 15.

Yesterday we reported on two new retractions for Potts-Kant in PLoS ONE, which earned her a spot in the top 30 on our leaderboard. As with the others, the latest paper, in the Journal of Clinical Investigation, is marred by “unreliable” data.

Here’s the retraction notice for “In utero supplementation with methyl donors enhances allergic airway disease in mice“:

Continue reading Duke researcher adds another retraction in JCI, bringing count to 15

Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

PLOS OneA pair of Duke researchers who each have more than 10 retractions have earned some more.

Both of the newly retracted papers — originally published in 2012 by PLOS ONE — list Erin Potts-Kant as a co-author; one includes her former supervisor, Michael Foster, as lead author. The pair has since left Duke (Potts-Kant was arrested for using school credit cards to shop at the likes of Target, and Foster retired). The reason provided for these retractions will be familiar to anyone who’s been following their case — there were “concerns about the reliability” of the data.

By our count, Potts-Kant now has 14 retractions, making her one of the few women to hold a position on our leaderboard.

Here’s the retraction notice for “Iron Supplementation Decreases Severity of Allergic Inflammation in Murine Lung,” a paper that lists both Foster and Potts-Kant as authors:

Continue reading Duke pulmonary researcher up to 14 retractions, putting her on our leaderboard

Physics journal pulls two papers for data shortcuts

New Journal of PhysicsA publisher is retracting two papers today by a team of physicists who took a short cut in reporting their data.

The papers present a method for imaging very small things — like biological processes on a molecular scale — that could be an alternative to electron microscopy, as the authors explain in a video. But after the papers were published in the New Journal of Physics, last author Ulf Leonhardt, now based at the Weizmann Institute of Science, found out that some of the data

 were pixel-by-pixel mirror-symmetric, which is impossible for genuine experimental data.

One of the researchers co-authored a subsequent paper that acknowledges one of the papers incorrectly assumed the data were symmetrical, and could therefore be extrapolated from one side to the other. A representative of the publisher told us they have not seen any signs of misconduct, and the problem seemed to result from a “series of apparent miscommunications between the authors.”

Here’s the retraction notice for “Evidence for subwavelength imaging with positive refraction:” Continue reading Physics journal pulls two papers for data shortcuts

Economics paper retracted due to “extensive changes”

727710An article has been retracted from a proceedings of an economics conference after the publisher identified errors in several parts of the study.

The retraction follows criticism from a Romanian blogger, who contacted the journal about several issues, and posted communications she received about the paper, “Sustainability of Social Enterprises: A Discourse Analysis.” It was part of a volume of Procedia Economics and Finance from a 2014 conference, “Economic Scientific Research – Theoretical, Empirical and Practical Approaches,” also known as ESPERA 2014.

According to the paper, peer review was

under responsibility of the Scientific Committee of ESPERA 2014.

Apparently, the peer review process missed a few errors. The retraction note explains:

Continue reading Economics paper retracted due to “extensive changes”