Category: society journal retractions

E. coli gene paper falls to mistaken mutation

asmcoverResearchers in Germany have retracted their 2011 article in the Journal of Bacteriology after another lab pointed out a fatal error in the paper.

The article, “Escherichia coli Exports Cyclic AMP via TolC,” came from a group at Tübingen University led by Klaus Hantke. The paper focuses on the crucial role of the membrane channel TolC in exporting cyclic AMP (cAMP)-cAMP receptor protein (CRP) complex, which regulates nearly 200 E. coli genes. According to the abstract:

The data demonstrate that export of cAMP via TolC is a most efficient way of E. coli to lower high concentrations of cAMP in the cell and maintain its sensitivity in changing metabolic environments.

But the conclusions rested on a gene mutation that wasn’t quite what it seemed. Here’s the notice: Continue reading E. coli gene paper falls to mistaken mutation

Singapore investigation leads to two retractions, two more on the way

cov150hAuthors have retracted papers from Cell Metabolism and the Journal of Biological Chemistry after an investigation in Singapore found issues, including falsified data. The investigation is ongoing, and two additional retractions, along with two corrections, are on the horizon.

The investigation looked into papers by first authors Sudarsanareddy Lokireddy, now a postdoc at Harvard, and Sandhya Sriram, a postdoc at the Agency for Science, Technology and Research in Singapore. Led by the Nanyang Technological University in Singapore, where some of the work was done, the investigation concluded that there were issues with six papers on which either Sriram or Lokireddy was first author.

All authors but Lokireddy have agreed to retractions or corrections. Ravi Kambadur of NTU, and Mridula Sharma at the National University of Singapore, are the last two authors on all the papers.

According to a notice from the NTU, the “investigation found a number of instances of alterations to data” in three papers on which Lokireddy is first author. One of those was retracted December 1 by Cell Metabolism: Continue reading Singapore investigation leads to two retractions, two more on the way

NSF investigating as more falsified results surface from mol bio researcher

Screen Shot 2015-12-04 at 5.22.53 PMAuthors of a paper on the origin and function of a family of transmembrane proteins have retracted it after an investigation at the University of Florida revealed that an author had falsified some results.

This is the third paper with falsifications that Chi Leung, a former UF postdoc, is responsible for; this summer, we reported on a retraction and a partial retraction of two other papers on which Leung was a co-author. The case is currently under investigation by the U.S. Office of Research Integrity National Science Foundation, a UF spokeswoman tells us.

The problems in the paper, “Phylogenetic, expression, and functional analyses of anoctamin homologs in Caenorhabditis elegans,” occur in a figure that compares mRNA levels in control and experimental populations of C. elegans. The paper was published in the American Journal of Physiology, and has been cited eight times, according to Thomson Scientific’s Web of Knowledge.

The retraction note explains that, according to the other authors, much of the data in the paper are valid:

Continue reading NSF investigating as more falsified results surface from mol bio researcher

Authors lied about ethics approval for study on obesity, depression

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Obesity has retracted a study that suggested overweight people may be less depressed than their slimmer counterparts in cultures where fat isn’t stigmatized, after realizing the authors lied about having ethical approval to conduct the research.

The authors claimed their research protocol had been approved by Norwegian and Bangladeshi ethical committees, but, according to the retraction note, part of the study “was conducted without the required approval of the university ethics board.” The journal’s managing editor told us that there is no evidence that there was harm to the study subjects.

Here’s more from the retraction note for “In Bangladesh, overweight individuals have fewer symptoms of depression than nonoverweight individuals:”

Continue reading Authors lied about ethics approval for study on obesity, depression

Astrophysicists issue two detailed corrections

1.coverA group of astrophysicists has notched a pair of corrections for papers on galaxy clusters, thanks to an error that affected several figures in the papers, but not the overall conclusions.

The errors came in the catalog of “mock” galaxies that first author Fabio Zandanel, a postdoc at the University of Amsterdam, created to model features that are found in clusters of galaxies. Two mistakes canceled each other out “almost perfectly,” says Zandanel, making the changes that resulted from them subtle.

Zandanel explained the errors to us:

Continue reading Astrophysicists issue two detailed corrections

Publisher error removes industry conflicts in vaccine paper

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An article about the use of vaccines against pertussis — also known as whooping cough — didn’t include the fact that the author has received grants and consultancy fees from three pharmaceutical companies that help make or sell the vaccines.

The correction to “Pertussis in young infants: a severe vaccine-preventable disease,” published in Autopsy and Case Reports just a few months after the paper, cites a “desktop publishing error” that led to the following problems: Continue reading Publisher error removes industry conflicts in vaccine paper

NEJM pulls letter by heart researcher who faked patient records

Screen Shot 2015-11-30 at 10.08.23 AMA heart researcher who fabricated patient records has notched retraction number six — this time, for a letter in the New England Journal of Medicine. She has two more retractions forthcoming.

The retraction comes at the request of Anna Ahimastos’s co-authors, following an investigation into her work by her former workplace, the Baker IDI Heart and Diabetes Institute. The investigation was not able to verify the data referenced in the letter, which includes a citation for a recently retracted JAMA paper.

The retraction note is similar to others for Ahimastos’s papers:

Continue reading NEJM pulls letter by heart researcher who faked patient records

Chemists pull non-reproducible paper on method to make opal films

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When two chemists based in China couldn’t reproduce experiments in their paper on opal films, they retracted it.

As the retraction note explains:

In this article we report a method to fabricate 2D TiO2–WO3 composite inverse opal films via a mechanical co-assembly route with a template of polystyrene spheres. Upon repeating the experiments described, we found that this was not an effective method for forming the films; often the film was broken or did not form at all.

The note also explains why the experiment didn’t work:

Continue reading Chemists pull non-reproducible paper on method to make opal films

Four JBC retractions add up to 8 in total for cancer research pair

47.coverThe Journal of Biological Chemistry is retracting four papers by a pair of cancer researchers at Tulane University, bringing their total to eight.

The retractions are all for reusing parts of figures, either within a paper or from other papers by the pair. Thanks to a new policy at the journal to publish informative notes, we know the figures that were problematic, and the papers that they borrow from. 

An investigation by Tong Wu and Chang Han’s former employer, the University of Pittsburgh, had already led to four retractions for the pair, including two issued this summer.

First up, “Activation of cytosolic phospholipase A2α through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2,” which has been cited 50 times, according to Thomson Scientific’s Web of Knowledge. Here’s the note: Continue reading Four JBC retractions add up to 8 in total for cancer research pair

Osteoporosis paper felled by concerns with “scientific integrity”

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A paper suggesting that exposure to sunlight might help prevent hip fractures in the elderly has been retracted, due to duplication and “concerns about the underlying data.”

An expression of concern that appeared last July flagged the 2005 paper as containing text that matched another paper with the same first author that was published in 2011. According to the publisher, that duplicated text sparked a closer look at the text, which raised concerns about the scientific integrity of the paper.

The retraction note, published by the Journal of Bone and Mineral Research, says that the first author was responsible for the content of the paper: Continue reading Osteoporosis paper felled by concerns with “scientific integrity”