Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

cov150hAn investigation into a paper that compared infection rates from different types of central lines started with an allegation about a failure to disclose a conflict of interest, and ended up concluding that the science in the paper was flawed.

The 2013 paper — now retracted by the American Journal of Infection Control — suggested a particular kind of connector between the catheter and the patient could reduce some of the notoriously deadly bloodstream infections associated with the procedure, according to a press release that publicized the work. But last year, the journal issued an expression of concern for the paper, noting there were questions about the data. The retraction note reveals an investigation at Georgia Regents University — now known as Augusta University — started looking into undisclosed conflicts of interest in the paper, and ultimately concluded the science was flawed.

Here’s the retraction note, published in the January 1st 2016 issue of the journal, for “Comparison of central line-associated bloodstream infection rates when changing to a zero fluid displacement intravenous needleless connector in acute care settings

Continue reading Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

What to do when you make a mistake? Advice from authors who’ve been there

cpp-150After a group of researchers noticed an error that affected the analysis of a survey of psychologists working with medical teams to help pediatric patients, they didn’t just issue a retraction — they published a commentary explaining what exactly went wrong.

The error was discovered by a research assistant who was assembling a scientific poster, and noticed the data didn’t align with what was reported in the journal. The error, the authors note, was:

an honest one, a mistake of not reverse coding a portion of the data that none of the authors caught over several months of editing and conference calls. Unfortunately, this error led to misrepresentation and misinterpretation of a subset of the data, impacting the results and discussion.

Needless to say, these authors — who use their “lessons learned” to help other researchers avoid similar missteps — earn a spot in our “doing the right thing” category. The retraction and commentary both appear in Clinical Practice in Pediatric Psychology.

Their first piece of advice in “Retraction experience, lessons learned, and recommendations for clinician researchers” — assume errors will happen, and not vice versa: Continue reading What to do when you make a mistake? Advice from authors who’ve been there

Following an earlier investigation, GW biologist earns two expressions of concern

3.cover (1)The Journal of Biological Chemistry has flagged two papers by a George Washington University cancer biologist with expressions of concern, following an investigation completed by the university in 2014.

The notes contain little specific information; all we know is that there are questions about the data and conclusions in the papers.

The last author on both papers is Rakesh Kumar, who adds these EoCs to a count that includes, according to our records, three retractions and five corrections. Plus an $8 million lawsuit against his employer for emotional distress when they put him on leave from his position as department chair.

The studies — “Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator” and “Regulation of NF-B circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis” — have been cited 22 times and 33 times respectively, according to Thomson Scientific’s Web of Knowledge.

The expression of concern is the same for both papers — and matches others that we’ve seen from JBC:

Continue reading Following an earlier investigation, GW biologist earns two expressions of concern

Paper on the adhesiveness of a material doesn’t stick

1-s2.0-S0169433215X00213-cov150hApplied Surface Science has retracted an article that looks at the structure of thin tungsten-titanium coating, because it was submitted without all of the co-authors’ consent.

According to the introduction of the paper, “Structure adhesion and corrosion resistance study of tungsten bisulfide doped with titanium deposited by DC magnetron co-sputtering,” such thin films are “widely used as a surface treatment for optimizing base material properties.”

Here’s the retraction note in full, published in the September issue of the journal:

Continue reading Paper on the adhesiveness of a material doesn’t stick

Wound healing paper injured beyond repair

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Errors in the interpretation of some of the data — the result of “procedural flaws” —  are to blame for the retraction of a paper on a way to help skin grow back after injury.

The paper explores a method involving nanofibers. According to the abstract:

In this study, tilapia skin collagen sponge and electrospun nanofibers were developed for wound dressing…the collagen nanofibers stimulated the skin regeneration rapidly and effectively in vivo.

The paper was published January 19, 2015 by ACS Applied Materials and Interfaces, then retracted eight months later, in August. It has not been cited, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note:

Continue reading Wound healing paper injured beyond repair

Science publishes Voinnet’s 19th, 20th, and 21st corrections

351-6271-coverProminent plant biologist Olivier Voinnet has issued three more corrections in this week’s issue of Science.

Collectively, the papers have earned more than 1400 citations, according to Thomson Scientific’s Web of Knowledge.

By our count, he’s now at 21 corrections and seven retractions, following months of questions about his work. He’s been the subject of an investigation that found he “breached his duty of care,” and another which found evidence of scientific misconduct.

One correction goes against the recommendation of the ETH Commission to retract the paper for “well documented intentional manipulations.” According to the correction note, the incorrect figures did not “alter the data in any material way that could be construed to benefit the results and their conclusions.” That correction is the only one of the three for which Voinnet takes full responsibility.

The other two corrections place the responsibility on  Continue reading Science publishes Voinnet’s 19th, 20th, and 21st corrections

You’ve been dupe’d: Meet authors who like their work so much, they publish it twice

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When our co-founders launched the site in 2010, they wondered whether there would be enough retractions to write about on a regular basis. Five+ years and three full-time staffers later, and we simply don’t have the time to cover everything that comes across our desk.

In 2012, we covered a group of duplication retractions in a single post, simply because duplications happen so frequently (sadly) and often don’t tell an interesting story. So in the interest of bookkeeping, we’re picking up the practice again.

Here are five unrelated retractions for your perusal: all addressing duplications, in which the same – or mostly the same – authors published the same – or mostly the same – information in two different – or sometimes the same – journals.

So, on the buffet table we offer the following entrees: Continue reading You’ve been dupe’d: Meet authors who like their work so much, they publish it twice

Can a journal retract its plan to retract? Science may

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Science is reconsidering its plan to retract a paper about using RNA to make palladium nanoparticles after one of the authors submitted a last-minute correction.

Editor in chief Marcia McNutt told us that the journal will make a decision about whether to retract or correct the paper by February 5th.

We are not certain that what he submitted changes anything, but we wanted to consider this new information before acting.

In the meantime, today the journal issued an Expression of Concern for the paper.

The journal’s initial decision to retract the paper stemmed from an investigation at the National Science Foundation, which concluded that co-authors Bruce Eaton and Dan Feldheim — currently at the University of Colorado at Boulder — engaged in “a significant departure from standard research practices,” and cut them off from NSF funding unless they took specific actions. When the report on the investigation came to light earlier this month, Science editor in chief Marcia McNutt told us that she planned to issue a retraction:

We are checking to see how soon we can get it published.

McNutt explained what changed:  Continue reading Can a journal retract its plan to retract? Science may

So, pot may not be as harmless as a recent study suggested

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Researchers are correcting a widely covered study that suggested chronic use of pot might not put users at risk of problems later in life.

It turns out that initial, unexpected finding — covered by Newsweek, The Washington Post, Quartzand (of course) The Stoner’s Cookbook (now known as HERB) wasn’t quite right, and a reanalysis found users had a small uptick in risk for psychosis. The authors have issued a lengthy correction in Psychology of Addictive Behaviors that includes some supplemental analysis, too.

Not surprisingly, the study’s findings engendered some controversy, which prompted the authors to reanalyze their data, collected from 408 males with varying levels of marijuana use, who were followed from their teens into their 30s.

Now, an American Psychological Association press release that accompanied the initial findings in August contains an editors note explaining why those aren’t quite correct:

Continue reading So, pot may not be as harmless as a recent study suggested

Lawsuit against Ole Miss for rescinded Sarkar job offer dismissed; briefs filed in PubPeer case

court caseWe recently obtained court documents showing that, in September, a judge dismissed a lawsuit filed by cancer researcher Fazlul Sarkar against the University of Mississippi after it rescinded a job offer after reviewing concerns raised about his research on PubPeer.

Sarkar’s connection to PubPeer will be familiar to many readers — he has also taken the site to court to force them to reveal the identity of the anonymous commenters who have questioned his findings. He has accused the commenters of defamation, arguing they cost him the job offer. Today, the American Civil Liberties Union filed a brief on behalf of PubPeer’s appeal of the court’s most recent ruling, that the site must disclose the identity of an anonymous commenter. At the same time, some heavy hitters in science – Bruce Alberts and Harold Varmus — and technology — Google and Twitter — filed briefs in support of the appeal.

The lawsuit against Ole Miss has brought to light the reasoning behind the school’s decision to rescind their offer to Sarkar — and the key role played by the concerns raised on PubPeer.

In a letter dated June 19, 2014 to Sarkar from Larry Walker, the director of the National Center for Natural Products Research at the University of Mississippi, Walker chides Sarkar for not revealing the extent of the ongoing questions over his research during the interview process:

Continue reading Lawsuit against Ole Miss for rescinded Sarkar job offer dismissed; briefs filed in PubPeer case