Head of major diagnostic lab in Canada steps down amid investigation

AJPA_v185_i7_COVER.inddA prominent endocrinologist pathologist has resigned from running the largest hospital diagnostic laboratory in Canada following an investigation that has uncovered evidence of falsified data in two papers, Retraction Watch has learned.

Sylvia Asa was the Program Medical Director of the Laboratory Medicine Program at the University Health Network, affiliated with the University of Toronto, until this past spring when she stepped down, according to UHN spokesperson Gillian Howard:

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What do you do after painful retractions? Q&A with Pamela Ronald and Benjamin Schwessinger

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Pamela Ronald and Benjamin Schwessinger, wearing the shirts of a swim competition they entered

2013 was a rough year for biologist Pamela Ronald. After discovering the protein that appears to trigger rice’s immune system to fend off a common bacterial disease – suggesting a new way to engineer disease-resistant crops – she and her team had to retract two papers in 2013 after they were unable to replicate their findings. The culprits: a mislabeled bacterial strain and a highly variable assay. However, the care and transparency she exhibited earned her a “doing the right thing” nod from us at the time.

After many months spent understanding what went wrong and redoing the experiments correctly, today Ronald and her team release another paper in Science Advances that reveals the protein they thought they had identified in 2013.

Ronald and co-first author Benjamin Schwessinger (who recently became an independent research fellow at the Australian National University in Canberra) spoke to us about the experience of recovering from the retractions and finally getting it right. The conversation has been edited for brevity and clarity.

-What did you do differently this time so you didn’t repeat the same mistakes?

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“Part of a paper that had already appeared”: Materials paper pulled for plagiarism

1-s2.0-S1387181115X00035-cov150hMicroporous and Mesoporous Materials has retracted a 2015 paper after it was discovered the authors “have plagiarized part of a paper that had already appeared.”

The paper, “Ionic liquid assisted synthesis of flexible and super-hydrophobic porous gels,” described the synthesis of a form of flexible aerogels “through a facile one-pot preparation,” according to the abstract. According to Thomson Scientific’s Web of Knowledge it has been cited zero times.

Here is the retraction note, in full:

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Author’s ties to NFL lead to correction for review that cast doubt on brain risk from sports

PLOS ONE

A review paper that suggested the degenerative brain disease that’s striking former football players may not be tied to contact sports has been corrected to reveal the first author spent decades working for the National Football League.

The correction appears in a review in PLOS ONE about chronic traumatic encephalopathy the degenerative brain disease that was the basis of a $765 million settlement for former NFL players, along with a number of similar lawsuits. It fixes incorrect statements and adds conflicts of interest, including those with with first author Joseph Maroon, who spent more than 30 years working with the NFL and seven for the wrestling group the WWE.

It appears as if all the original paper declared was that Maroon was an “unpaid consultant” to the Pittsburgh Steelers. But apparently there was a lot more to it, according to the notice:

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Data “mismatch” and author’s illness pluck bird sex-ratio study from literature

coverInaccessible data and an author’s illness are to blame for the retraction of a paper on sex ratios of baby finches, according to the authors.

The paper, “Experimental evidence that maternal corticosterone controls adaptive offspring sex ratios,” published in Functional Ecology, outlined how a hormone in mother finches can “skew” the number of males vs females that hatch from the eggs in her nest.

But after questions about the data were raised, the authors were unable to address the “mismatch” between the experimental data and those that were published. Compounding the situation is the fact that, while working on the paper, first author Sarah Pryke at the Australian National University “was suffering from a medical condition that likely impaired her cognitive abilities,” according to a statement from Pryke’s co-authors.

An email to Pryke was met with an out-of-office reply:

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Cell biologist Hanna issues two errata; images mysteriously disappear from Imgur

Jacob Hanna
Jacob Hanna

Cell biologist Jacob Hanna, the highly cited stem cell researcher currently at the Weizmann Institute of Science,  has posted a long erratum for a 2005 paper in Blood for “inadvertent mistakes,” among other issues; soon after, Hanna’s team issued another erratum for a 2009 Cell Stem Cell paper.

There’s more to tell: Last month, commenters on PubPeer noticed that images from at least 10 of the research papers Hanna coauthored in seven journals — that commenters had posted on the image hosting website Imgur and linked to on PubPeer — had been deleted.

Imgur did not confirm whether these specific images had been deleted, but told Retraction Watch:

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Second correx for controversial paper on the financial benefits of climate change

Journal of Economic PerspectivesThe Journal of Economic Perspectives has published a second correction for a 2009 paper that argued that some amount of global warming could lead to economic gains.

The author of “The Economic Effects of Climate Change,” Richard Tol, a professor of economics at the University of Sussex, blamed earlier problems with the paper on “gremlins.” In a notice posted last year, Tol wrote that “minus signs were dropped”; he also added a pair of “overlooked estimates” and several recently published studies.

After the first correction was published, several people contacted the JEP to point out more issues with the paper. Editors worked with Tol and outside researchers to update the paper again.

Here’s some text from the newest correction notice:

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“There has been negligence”: Biologist banned for one year by German funding agency

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Jens Christian Schwamborn

As a consequence for academic “negligence” which resulted in two retractions, biologist Jens Schwamborn was banned from seeking funding from German funding agency DFG for one year.

The ban — which ended in March, 2015 — was the result of an investigation by DFG and the University of Münster, which reviewed the issues that led to retractions of two papers about neuron development, one in The EMBO Journaland another in the Journal of Biological Chemistry

Here’s the official statement on the ban, sent to us by Head of Communications Britta Schlüter at the University of Luxembourg, where Schwamborn now works:

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Duke lung researcher up to seven retractions

Enviromental Health Perspectives

More journals have pulled papers co-authored by researchers Erin Potts-Kant and Michael Foster, at Duke University, bringing the total up to seven for Potts-Kant and six for Foster.

Authors were unable to replicate the experiments after “concerns about the initial data from the animal physiology laboratory” led them to reanalyze source data, according to the note in Environmental Health Perspectives. The comparison showed “potential inconsistencies in the data,” which “significantly impact the overall conclusions of the manuscript.” Similar issues appear to have felled the pair’s other papers, including the other two recent retractions in the American Journal of Respiratory and Critical Care Medicine and the American Journal of Physiology – Lung Cellular and Molecular Physiology — but in the latter case, the discrepancies don’t affect the conclusion.

Potts-Kant was arrested on embezzlement charges in 2013. Authorities alleged that she stole almost $15,000 from Duke University.

Environmental Health Perspectives posted a retraction in July, for a 2012 paper that looked at the molecular underpinnings in airways that react to ozone.

Here’s the full notice:

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“To our horror”: Widely reported study suggesting divorce is more likely when wives fall ill gets axed

home_coverA widely reported finding that the risk of divorce increases when wives fall ill — but not when men do — is invalid, thanks to a short string of mistaken coding that negates the original conclusions, published in the March issue of the Journal of Health and Social Behavior.

The paper, “In Sickness and in Health? Physical Illness as a Risk Factor for Marital Dissolution in Later Life,” garnered coverage in many news outlets, including The Washington Post, New York magazine’s The Science of Us blog, The Huffington Post, and the UK’s Daily Mail 

But an error in a single line of the coding that analyzed the data means the conclusions in the paper — and all the news stories about those conclusions — are “more nuanced,” according to first author Amelia Karraker, an assistant professor at Iowa State University.

Karraker — who seems to be handling the case quickly and responsibly —  emailed us how she realized the error:

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