Category: united states

More black marks against unapproved protein touted as miracle cure

clinical immunologyA protein which is sold online as a cure for everything from autism to cancer and the focus of multiple retracted papers has earned more black marks: The UK government’s Medicines and Healthcare Products Regulatory Agency has issued a warning about its use after discovering problems in the factory, and a journal has removed the last author from a paper touting its benefits in HIV.

The protein, vitamin D-binding protein-derived macrophage activating factor (GcMAF), is supposedly a natural activator of macrophages. The website GcMAF.eu continues to hawk the results of treatment, while the Anticancer Fund has been pushing journals to correct the record on GcMAF. Continue reading More black marks against unapproved protein touted as miracle cure

Harvard-Smithsonian space center retracts ruling on asteroid

Image of near Earth astroid Ida, via NASA
Image of main-belt asteroid Ida, via NASA

Between Mars and Jupiter floats a little rock with big dreams.

For three whole weeks in January and February, it was designated as 2015 BS515, a near Earth object, one of the many space rocks that astrophysicists keep an eye on for their potential to strike our planet. But then on February 12 came the announcement: the Minor Planet Center (MPC) at the Harvard-Smithsonian Center for Astrophysics had downgraded the rock to a “routine main-belt object.” That means the asteroid is far enough away that we don’t have to worry about it hitting Earth any time soon.

The MPC gets sent two million observations of asteroids and comets every month. The five staff members then catalog these findings and figure out what’s new and what’s been seen before. The goal is to keep track of all near Earth objects, which make up about 1% of the observations the Center receives. It’s remarkable that there are so few corrections, given the 120 million observations on the MPC’s books.

Here’s a portion of the note that appeared in the most recent Minor Planet Electronic Circular (MPEC), which provides updates about comets, “observable unusual objects,” and other asteroid news: Continue reading Harvard-Smithsonian space center retracts ruling on asteroid

Science chemistry paper earns retraction after expression of concern, marking second for UT group

scienceThe authors of a 2011 Science paper that proposed a new way to direct chemical bonds have withdrawn the paper after concerns about the data prompted an investigation and Editorial Expression of Concern last year from the journal. The retraction is the second for the group, which has also had seven other expressions of concern.

After a reader emailed the editors to raise suspicions about the data, corresponding author Christopher W. Bielawski, then based at the University of Texas at Austin, led an investigation of all the figures. It found substantial problems: “In over 50% of the figure parts, the authors deemed the data unreliable due to uncertainty regarding the origin of data or the manner in which the data were processed,” according to the retraction notice.

UT Austin concluded that there had been misconduct, but did not elaborate.

Continue reading Science chemistry paper earns retraction after expression of concern, marking second for UT group

Misconduct forces retraction of health behavior paper

j behav medA pair of psychology researchers at West Virginia University have lost their 2013 article in the Journal of Behavioral Medicine after one of the authors was found to have cooked the data.

The paper, “Preference for immediate reinforcement over delayed reinforcement: relation between delay discounting and health behavior,” was written by Shane Melanko and Kevin Larkin. It examined whether people who place less importance on the future were also less likely to adopt healthy behaviors, which come with delayed benefits. Melanko, then a doctoral candidate under Larkin, was evidently at one time a psychology student of some promise.

That promise might go unfulfilled. According to the retraction notice: Continue reading Misconduct forces retraction of health behavior paper

Matlab mixup sinks Journal of Neuroscience paper

journal of neuroscienceA team of neuroscientists at University of Oregon and the University of California, San Diego (UCSD) have retracted a paper from The Journal of Neuroscience after realizing their analytic code contained an error.

The authors state in the notice that their conclusion remains accurate after correcting the mistake in the program Matlab. However, the paper — which examined the role of neuronal oscillations in working memory — still contained “some findings that we no longer believe to be robust.”

It’s a very useful notice: Continue reading Matlab mixup sinks Journal of Neuroscience paper

Exclusive: St. Jude Children’s suspends enrollment in cancer trials over toxicity concerns

st judesSt. Jude Children’s Research Hospital in Memphis has temporarily halted enrollment in six bone marrow transplant trials due to concerns over how side effects were being identified in medical records, Retraction Watch has learned.

According to a source familiar with the trials, five of the six being suspended were all enrolling children with blood cancers who lacked a matching donor. During the trials, doctors took bone marrow from a parent — not a perfect match — and manipulated the cells before transplant to make them more capable of killing cancer, and less likely to be rejected.

Four trials, a few of which were scheduled to enroll more than 100 children, are being led by Brandon Triplett. Two are led by Mari Dallas, according to the source. Genzyme and the U.S. National Cancer Institute are listed as collaborators. Both Dallas and Triplett work under bone marrow transplant department chair Wing Leung.

We reached out to Scientific and Comprehensive Cancer Center Director Richard Gilbertson, who referred us to PR firm Rubenstein Public Relations. They sent us the following statement: Continue reading Exclusive: St. Jude Children’s suspends enrollment in cancer trials over toxicity concerns

Forged author list blows up explosives contamination paper

WWII poster for Ravenna Ordnance Plant, via Wikipedia
WWII poster for Ravenna Ordnance Plant, via Wikipedia

An environmental journal has retracted a paper on a technology that helps degrade explosives released into soil, because the first author never got the permission of his “co-authors” — oh, and used data that were “illegally obtained,” according to one of the slighted co-authors.

According to the EPA, more than 30 sites around the country are contaminated by decommissioned explosives, including weapons plants and army depots. A major source of the pollution was workers washing out old bombs into “evaporation lagoons” and then burning the resulting sludge.

The site used for the retracted paper was Ravenna Army Ammunition Plant, a decommissioned weapons factory that stored explosive waste in unlined landfills. According to the EPA, “open burning was also a common practice.”

The problems with the paper in Water, Air & Soil Pollution were uncovered after the head of the company, University of Georgia (UGA) professor Valentine Nzengung, found the paper on ResearchGate. He discovered that first author Chunhui Luo had used (now out-of-date) data without permission, and added Nzengung’s name to the paper without his knowledge. The other author is another UGA professor, Walter O’Niell, who told us he was also not informed about the paper.

Nzengung gave us further details via email: Continue reading Forged author list blows up explosives contamination paper

Chem paper retracted because “a significant amount of data” was wrong

Jced_coverThe editors of ACS’s Journal of Chemical and Engineering Data have sunk a paper on halogenated alkanes after realizing that “a significant amount” of the data was “inaccurate,” thereby “invalidating” the paper.

Here’s the notice for “Influence of Solvent Nature on the Solubility of Halogenated Alkanes” (which has only been cited twice, according to Google Scholar): Continue reading Chem paper retracted because “a significant amount of data” was wrong

Figure dupe sinks cell bio paper

cellular biohemTulane researchers Tong Wu and Chang Han, who have been anonymously accused of figure duplication in the past, have now finally lost a paper for that reason.

The frequent plagiarism tipster Juuichi Jigen (a pseudonym) set up a blog in 2012 alleging that the pair inappropriately reused images in six other papers, though none of those have been retracted. The recent notice, issued at the end of January by the Journal of Cellular Biochemistry, states that the figure duplication was confirmed by the University of Pittsburgh’s Office of Research Integrity. Han, the first author, was at UPitt when the paper was published in 2008, though she moved to join Wu at Tulane in 2009.

Here’s the notice for “Regulation of Wnt/ß-Catenin Pathway by cPLA2α and PPARδ“: Continue reading Figure dupe sinks cell bio paper

Fourth retraction appears for cancer researcher Anil Jaiswal

cancer research 1113The hits keep coming for University of Maryland researcher Anil Jaiswal.

The latest retraction for the cell biologist is in Cancer Research, for a 2007 paper about ways in which the cell tries to protect the tumor suppressor p53. Like the first Jaiswal retraction we covered, the latest notice specifically taps figure duplication as the cause of death, “as a result of an error.” The other two retractions gave no explanation for the withdrawal.

Here’s the notice: Continue reading Fourth retraction appears for cancer researcher Anil Jaiswal