Category: united states

MD Anderson researcher Aggarwal up to six corrections

cover (2)A highly cited cancer researcher at MD Anderson has notched three major corrections, all associated with problems in figures. One note cites “human error” as the cause.

Bharat Aggarwal is the last author on all three papers. He is now up to six corrections, two unexplained withdrawals, and two Expressions of Concern. He’s also threatened to sue us in the past, and has told us that his institution has been looking into his work.

Only one note specifies that the correction does not affect the paper’s conclusions.

First up: “Inhibition of growth and survival of human head and neck squamous cell carcinoma cells by curcumin via modulation of nuclear factor-κB signaling,” published in the International Journal of Cancer and cited 168 times, according to Thomson Scientific’s Web of Knowledge. The issues span two figures, according to the erratum note:

Continue reading MD Anderson researcher Aggarwal up to six corrections

Heart researcher gets 3rd retraction for copying images of rat hearts

1-s2.0-S0014299914X00233-cov150hWhen two papers include the same images of rat hearts, one of those papers gets retracted.

The papers share a corresponding author, Zhi-Qing Zhao of Mercer University School of Medicine in Savannah, Georgia. This marks his third retraction; we reported on two others earlier this year.

The papers examine the effect of curcumin, which has antinflammatory properties (in addition to giving the spice turmeric its yellow color). The retracted paper, “Dual ACE-inhibition and angiotensin II AT1 receptor antagonism with curcumin attenuate maladaptive cardiac repair and improve ventricular systolic function after myocardial infarctionin rat heart,” was published in the January 5, 2015 issue of the European Journal of Pharmacology, and has zero citations, according to Thomson Scientific’s Web of Knowledge. It shares multiple figures with another 2012 paper, “Curcumin promotes cardiac repair and ameliorates cardiac dysfunction following myocardial infarction,” published in the British Journal of Pharmacology, which has not been retracted. The BJP paper has been cited 18 times.

Here’s the retraction note for the EJP paper:

Continue reading Heart researcher gets 3rd retraction for copying images of rat hearts

Chronic fatigue syndrome-XMRV researcher scheduled to head to court today, alleging conspiracy

Judy Mikovits
Judy Mikovits

Chronic fatigue syndrome researcher Judy Mikovits was scheduled to head is heading to court today, where a California judge will would decide whether or not to dismiss her lawsuit against fourteen people and two Nevada corporations.

(Note: This story has been updated. See below.)

Among the defendants: the Whittemore Peterson Institute  in Reno, Nevada where Mikovits used to work; the institute’s cofounders, Annette and Harvey Whittemore; a colleague with whom she shares a retracted Science paper; and several members of California and Nevada law enforcement.

The complaint does not check the box next to “Money Demanded in Complaint”, but also lists $750,000 in the associated field:

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In 2006, Mikovits began working for the Whittmores at the WPI; her job was to search for a biological cause of chronic fatigue, a vexing, mysterious disease afflicting their daughter. Part of her research focused on a potential link between chronic fatigue syndrome and a virus known as XMRV. But after others — and Mikovits herself — couldn’t replicate results published in Science and the paper was retracted, she was fired from her position in 2011. Mikovits alleges that Continue reading Chronic fatigue syndrome-XMRV researcher scheduled to head to court today, alleging conspiracy

Nutritionist group pulls position statement on vegetarian diets for “inaccuracies and omissions”

Screen Shot 2015-10-16 at 11.57.38 AMWhat are the specific health benefits to skipping out on meat? We’re not totally sure, after the largest organization for nutrition professionals pulled its 2015 position statement on this issue only weeks after publishing it in the Journal of the Academy of Nutrition and Dietetics.

The “Position of the Academy of Nutrition and Dietetics: Vegetarian Diets” was removed earlier this year for “inaccuracies and omissions critical to the paper” — and the first author wasn’t told what they were. A “major revision” is forthcoming.

Here’s the removal note from the journal for the 2015 version:

Continue reading Nutritionist group pulls position statement on vegetarian diets for “inaccuracies and omissions”

Can linguistic patterns identify data cheats?

JLAPSCunning science fraudsters may not give many tells in their data, but the text of their papers may be a tipoff to bad behavior.

That’s according to a new paper in the Journal of Language and Social Psychology by a pair of linguists at Stanford University who say that the writing style of data cheats is distinct from that of honest authors. Indeed, the text of science papers known to contain fudged data tends to be more opaque, less readable and more crammed with jargon than untainted articles.

The authors, David Markowitz and Jeffrey Hancock, also found that papers with faked data appear to be larded up with references – possibly in an attempt to make the work more cumbersome for readers to wade through, or to tart up the manuscript to make it look more impressive and substantial. As Markowitz told us: Continue reading Can linguistic patterns identify data cheats?

Intellectual property issues sink cancer paper in JACS

176 spine minimum. full size. Editor: Lingling JEM: Leslie RTP: Michael ReidThe authors of a paper on a mechanism for potential cancer therapies are retracting it after realizing they published some proprietary findings “without permission and agreement from St. Jude Children’s Research Hospital.”

According to the retraction note in Journal of the American Chemical Society, the authors included an X-ray crystal structure and data that were gathered at St. Jude’s and considered the hospital’s intellectual property. On the paper, the last author, Zhengding Su, listed an affiliation at St. Jude and Hubei University of Technology in China, along with Amersino Biodevelop Inc., based in Waterloo, Canada.

Here’s the note for “Efficient Reactivation of p53 in Cancer Cells by a Dual MdmX/Mdm2 Inhibitor:”  Continue reading Intellectual property issues sink cancer paper in JACS

“Most responsible course of action is to retract:” Duplicated images fell prostate cancer paper

International Journal of CancerA study on the cellular interactions underlying prostate cancer has been retracted after a whistleblower pointed out duplicated images in one of the paper’s figures that were “erroneously presented as unique.”

The International Journal of Cancer posted the notice in June. The authors backed the paper’s conclusions but agreed, “the most responsible course of action is to retract.”

The notice reads:

Continue reading “Most responsible course of action is to retract:” Duplicated images fell prostate cancer paper

St. Jude investigation finds faked data in brain tumor paper

S00396060An investigation at St. Jude Children’s Hospital into “irregularities” in a figure featured in a neuroblastoma paper has concluded that the image was fabricated. The paper, published in Surgery in 2012, was retracted on Friday.

Here’s the full retraction notice for “Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition:”

Continue reading St. Jude investigation finds faked data in brain tumor paper

Study claiming dramatically higher rates of male military sexual trauma is retracted

psychological servicesA study that found a 15-fold increase in the rate of sexual trauma among men in the U.S. military — and sparked suggestions of “an epidemic of male-on-male sex crimes” in the military among conservative media outlets — has been retracted because of a flaw in the analysis.

The study, published just last week, appeared in Psychological Services, an American Psychological Association (APA) journal. In an announcement Sunday titled “American Psychological Association Retracts Article Positing Excessively High Rates of Sexual Trauma Among Military Men,” the APA said that “Scholars raised valid concerns regarding the design and statistical analysis which compromise the findings.” Here’s the text: Continue reading Study claiming dramatically higher rates of male military sexual trauma is retracted

Child psych studies halted for “unanticipated event,” sparking misconduct investigation

mpavuluri
Mani Pavuluri

We’ve just learned what sparked a University of Illinois at Chicago investigation that recently concluded a child psychiatrist had committed misconduct: An “unanticipated event during a study,” which halted three studies and resulted in a letter sent out to 350 research subjects.

Earlier this week, we reported that an investigation at the University of Illinois at Chicago found “a preponderance of evidence” that child psychiatrist Mani Pavuluri had committed misconduct. The university told the U.S. Department of Health and Human Services about the investigation in 2013. The findings of the investigation led the university to request the retractions of three papers, one of which has been pulled so far, for not properly disclosing how much medication children had received outside the study.

Today, we found out what prompted the university to launch that investigation, courtesy of a statement from a spokesperson: Continue reading Child psych studies halted for “unanticipated event,” sparking misconduct investigation