Category: united states

Intellectual property issues sink cancer paper in JACS

176 spine minimum. full size. Editor: Lingling JEM: Leslie RTP: Michael ReidThe authors of a paper on a mechanism for potential cancer therapies are retracting it after realizing they published some proprietary findings “without permission and agreement from St. Jude Children’s Research Hospital.”

According to the retraction note in Journal of the American Chemical Society, the authors included an X-ray crystal structure and data that were gathered at St. Jude’s and considered the hospital’s intellectual property. On the paper, the last author, Zhengding Su, listed an affiliation at St. Jude and Hubei University of Technology in China, along with Amersino Biodevelop Inc., based in Waterloo, Canada.

Here’s the note for “Efficient Reactivation of p53 in Cancer Cells by a Dual MdmX/Mdm2 Inhibitor:”  Continue reading Intellectual property issues sink cancer paper in JACS

“Most responsible course of action is to retract:” Duplicated images fell prostate cancer paper

International Journal of CancerA study on the cellular interactions underlying prostate cancer has been retracted after a whistleblower pointed out duplicated images in one of the paper’s figures that were “erroneously presented as unique.”

The International Journal of Cancer posted the notice in June. The authors backed the paper’s conclusions but agreed, “the most responsible course of action is to retract.”

The notice reads:

Continue reading “Most responsible course of action is to retract:” Duplicated images fell prostate cancer paper

St. Jude investigation finds faked data in brain tumor paper

S00396060An investigation at St. Jude Children’s Hospital into “irregularities” in a figure featured in a neuroblastoma paper has concluded that the image was fabricated. The paper, published in Surgery in 2012, was retracted on Friday.

Here’s the full retraction notice for “Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition:”

Continue reading St. Jude investigation finds faked data in brain tumor paper

Study claiming dramatically higher rates of male military sexual trauma is retracted

psychological servicesA study that found a 15-fold increase in the rate of sexual trauma among men in the U.S. military — and sparked suggestions of “an epidemic of male-on-male sex crimes” in the military among conservative media outlets — has been retracted because of a flaw in the analysis.

The study, published just last week, appeared in Psychological Services, an American Psychological Association (APA) journal. In an announcement Sunday titled “American Psychological Association Retracts Article Positing Excessively High Rates of Sexual Trauma Among Military Men,” the APA said that “Scholars raised valid concerns regarding the design and statistical analysis which compromise the findings.” Here’s the text: Continue reading Study claiming dramatically higher rates of male military sexual trauma is retracted

Child psych studies halted for “unanticipated event,” sparking misconduct investigation

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Mani Pavuluri

We’ve just learned what sparked a University of Illinois at Chicago investigation that recently concluded a child psychiatrist had committed misconduct: An “unanticipated event during a study,” which halted three studies and resulted in a letter sent out to 350 research subjects.

Earlier this week, we reported that an investigation at the University of Illinois at Chicago found “a preponderance of evidence” that child psychiatrist Mani Pavuluri had committed misconduct. The university told the U.S. Department of Health and Human Services about the investigation in 2013. The findings of the investigation led the university to request the retractions of three papers, one of which has been pulled so far, for not properly disclosing how much medication children had received outside the study.

Today, we found out what prompted the university to launch that investigation, courtesy of a statement from a spokesperson: Continue reading Child psych studies halted for “unanticipated event,” sparking misconduct investigation

Authors withdraw two papers from JBC — and that’s all we know

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Two sets of authors have withdrawn their papers from the Journal of Biological Chemistry. We’re telling you about the both together because, true to JBC form, there’s not too much to say.

The retraction notices for both papers — about the molecular underpinnings of cardiac fibroblasts and melanoma cells — are identical:

Continue reading Authors withdraw two papers from JBC — and that’s all we know

Got the blues? You can still see blue: Popular paper on sadness, color perception retracted

home_coverA paper published in August that caught the media’s eye for concluding that feeling sad influences how you see colors has been retracted, after the authors identified problems that undermined their findings.

The authors explain the problems in a detailed retraction note released today by Psychological Science. They note that they found sadness influenced how people see blues and yellows but not reds and greens, but they needed to compare those findings to each other in order to prove the validity of the conclusion. And once they performed that additional test, the conclusion no longer held up.

In the retraction note for “Sadness impairs color perception,” the editor reinforces that there was no foul play:

Continue reading Got the blues? You can still see blue: Popular paper on sadness, color perception retracted

Mega-correction to several images in gastric cancer study

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A journal has issued a rather large correction — what we call “mega-correction” — to a 2014 paper on a gastric cancer biomarker that fixes problems with several of the study’s figures.

The authors write that despite the corrections, “the results and conclusions put forth in the article remain unchanged.”

The paper, “TMEFF2 Deregulation Contributes to Gastric Carcinogenesis and Indicates Poor Survival Outcome” explored the role of TMEFF2 in gastric cancer. The researchers found that the protein acts as a tumor suppressor, and low levels can indicate the presence of cancerous cells.

Here’s the full correction notice, published by Clinical Cancer Research in August:

Continue reading Mega-correction to several images in gastric cancer study

Authors object to duplication verdict by environmental journal

10661An environmental journal has pulled a 2011 paper following an investigation, which revealed it contained “extensive similarities” with another paper published two years earlier by some of the same authors.

Two of the authors of the newly retracted paper — Zulfiqar Ahmad from Quaid-i-Azam University and Arshad Ashraf of the National Agricultural Research Center, both in Islamabad, Pakistan — were the sole authors of a 2008 paper about modeling groundwater flow in Indus Basin, Pakistan. The 2011 paper  — posted online in 2010 — focused on the same topic, but included two additional authors, one of whom told us he was unaware of the previous paper and agrees with the journal’s decision. Ahmad, however, has defended the 2011 paper and asked that the journal remove the retraction note.

Here’s the note, published in April by Environmental Monitoring and Assessment: Continue reading Authors object to duplication verdict by environmental journal

University finds “preponderance of evidence” of misconduct by child psychiatrist

JPN39_2_CoverAn investigation at the University of Illinois at Chicago has found “a preponderance of evidence” that a psychiatrist who has received millions of dollars in federal funding has committed misconduct.

One paper co-authored by Mani Pavuluri, the director of the Pediatric Mood Disorders Program, has been officially retracted so far, from the Journal of Psychiatry & Neuroscience. UIC has requested that two others be retracted as well. None of the child participants in the three papers received medication as part of the research, but the Journal of Psychiatry & Neuroscience paper was pulled after the investigation found that Pavuluri had misrepresented how much medication some children had taken outside of the study.

On Tuesday, after we’d learned of the first retraction, Pavuluri told Retraction Watch that she didn’t “want mountains made out of molehills,” but admitted to “a bit of an [Institutional Review Board] infraction.”

The retraction note from the Journal of Psychiatry & Neuroscience lays the blame squarely on Pavuluri’s shoulders:

Continue reading University finds “preponderance of evidence” of misconduct by child psychiatrist