Cancer biology group notches sixth retraction, and earns an Expression of Concern

bjcA group at the University of Texas Southwestern that retracted five papers last year has retracted one more, and has had a paper subjected to an Expression of Concern at the request of the school’s dean.

Here’s the retraction notice for “DNA methylation-associated inactivation of TGFβ-related genes, DRM/Gremlin, RUNX3, and HPP1 in human cancers,” originally published in the British Journal of Cancer and cited 51 times, according to Thomson Scientific’s Web of Knowledge:
Continue reading Cancer biology group notches sixth retraction, and earns an Expression of Concern

UCLA probe ends in retraction for neuroscience post-doc

jneuroscoThe Journal of Neuroscience has retracted a 2011 paper by a group of UCLA researchers after the institution concluded that a post-doc at the institution had falsified data.

The article, “Epigenetic Enhancement of BDNF Signaling Rescues Synaptic Plasticity in Aging,” came from the lab of Cui-Wei “Tracy” Xie, a behavioral scientist. It has been cited 42 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction notice: Continue reading UCLA probe ends in retraction for neuroscience post-doc

Rats! Neuroscientist notches third retraction, this one for using the wrong RNAs

biol psychAmine Bahi, a neuroscience researcher in the United Arab Emirates, has had a third paper retracted.

Here’s the notice for “Blockade of Protein Phosphatase 2B Activity in the Amygdala Increases Anxiety- and Depression-Like Behaviors in Mice,” which was posted on November 19: Continue reading Rats! Neuroscientist notches third retraction, this one for using the wrong RNAs

Former federal contractor faked data, says ORI

oriweb_logoThe Office of Research Integrity has found that Timothy Sheehy, formerly a scientist at a contractor for the Frederick National Laboratory for Cancer Research, committed misconduct in work paid for by the National Cancer Institute (NCI), National Institutes of Health (NIH), and a contract to his former company, SAIC-Frederick, Inc.

According to a notice in the Federal Register today, ORI found faked data in a 2010 paper, “Simultaneous Recovery of DNA and RNA from Formalin-Fixed Paraffin-Embedded Tissue and Application in Epidemiologic Studies,” that Sheehy and colleagues published in Cancer Epidemiology, Biomarkers, & Prevention: Continue reading Former federal contractor faked data, says ORI

Drug withdrawal: St. Louis Krokodil paper disappears

ajmedOn November 11, St. Louis’s KTVI reported that krokodil, a nasty opioid concoction with roots in Russia, had arrived in their town. They based that report on a case study published in the American Journal of Medicine, “Krokodil’—A Designer Drug From Across the Atlantic, with Serious Consequences,” and interviewed two of the paper’s authors, Dany Thekkemuriyil and Unnikrishnan Pillai.

The case study involved a 30-year-old man the Thekkemuriyil and Pillai said they had seen at St. Mary’s Health Center in Richmond Heights, Missouri. As the St. Louis Post-Dispatch reported a few days later: Continue reading Drug withdrawal: St. Louis Krokodil paper disappears

At long last, disputed dance study retracted from Nature

trivers natureA 2005 Nature study that has vexed one of its authors since 2007 is finally being retracted.

The notice for “Dance reveals symmetry especially in young men,” by William M. Brown, Lee Cronk, Keith Grochow, Amy Jacobson, C. Karen Liu, Zoran Popovic´& Robert Trivers, says very little: Continue reading At long last, disputed dance study retracted from Nature

Cancer researchers retract two papers in the JBC

jbcTwo cancer researchers who hold a patent on a particular pathway that might be a target for new drugs — and one of whom leads a company that is studying those potential drugs — have retracted two related papers in the Journal of Biological Chemistry (JBC).

The notices for “Kinase suppressor of Ras signals through Thr269 of c-Raf-1” and “The kinase activity of kinase suppressor of Ras1 (KSR1) is independent of bound MEK,” which share H. Rosie Xing and Memorial Sloan-Kettering’s Richard Kolesnick as authors, say the same thing: Continue reading Cancer researchers retract two papers in the JBC

Columbia University misconduct retraction highlights what’s wrong with the retraction process

jcacoverThe Journal of Clinical Anesthesia has a retraction of a 2006 paper by a group from Columbia University that, to our minds, is the poster child for how not to handle such things.

The article, “Dexmedetomidine infusion is associated with enhanced renal function after thoracic surgery,” was written by Robert J. Frumento, Helene G. Logginidou, Staffan Wahlander, Gebhard Wagener, Hugh R. Playford and Robert N. Sladen, who now is chief of critical care at the institution. The paper has been cited 30 times, according to Thomson Scientific’s Web of Knowledge.

Why do we bother to name all the authors? Here’s why: According to the retraction notice, one of them — but don’t ask which — is guilty of research misconduct: Continue reading Columbia University misconduct retraction highlights what’s wrong with the retraction process

Harvard student publication retracts article saying Jews deserve punishment because “they killed Jesus”

ichthusA Harvard student publication has retracted an article arguing that Jews deserved the persecution they’ve received for 2,000 years because they “killed Jesus.”

(We’ll do a few conflict of interest disclosures, if just for the hell — oops — of it: Harvard is Ivan’s alma mater, and both of us are well, Jews. We note, however, that the Ichthus was not around in Ivan’s Harvard days, and neither of us was around when the events involving Jesus described in this post occurred.)

As Talking Points Memo reported Thursday: Continue reading Harvard student publication retracts article saying Jews deserve punishment because “they killed Jesus”

Duplication leads to recall of toxicology paper

toxinvitroA group of researchers from Egypt and the United States has lost their 2010 paper in the journal Toxicology in Vitro for recycling many of their own words from a previously published manuscript.

The article, “Bacterial lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro,” was written by Hamdy A.A. Aly, Hany A. El-Shemy and David A. Lightfoot,  a professor of biotechnology and genomics at Southern Illinois University in Carbondale. El-Shemy, now of Cairo University, was a visiting scholar at SICU a few years ago, and he and Lightfoot have published together several times. Continue reading Duplication leads to recall of toxicology paper