Lancet retracts 24-year-old paper by “father of nutritional immunology” after reopening inquiry

lancetFollowing questions from outside experts, a retraction of a related paper, a university investigation and a court case, The Lancet has decided to retract a 1992 paper by Ranjit Kumar Chandra, the self-proclaimed “father of nutritional immunology.

In a lengthy retraction note included in the January 30 issue, the journal explains that:

the balance of probabilities in our judgment is that the reliability of the 1992 Lancet paper by Chandra can no longer be assured.

Chandra is objecting to the retraction.

This retraction was a long time coming, so sit back and relax as we fill in the backstory. Continue reading Lancet retracts 24-year-old paper by “father of nutritional immunology” after reopening inquiry

“Innocent mistake” leads to bioethics article retraction

jbiA July article that incorrectly called out nine leading bioethics journals for their lack of availability to researchers in low- and middle-income countries is being pulled after editors of the indicted journals refuted the allegations.

The last author on the article, published in the Journal of Bioethical Inquiry, told us an “innocent mistake” and difficulty navigating a website led the authors to incorrectly note that nine journals had not made their contents available through the World Health Organization’s Health InterNetwork Research Initiative database (HINARI), which gives bioethicists who live in low- and middle-income countries access to research articles either free of charge or at reduced cost. The authors argued that the mistake didn’t affect the paper’s conclusions, but the journal disagreed, and opted to pull the paper entirely.

After searching through the database, first author Subrata Chattopadhyay mistakenly determined that the journals had not made their contents available through HINARI, when in fact they were listed but on a different part of the website.

Even with the error, the authors maintain that their conclusions remain sound and that the field is shaped by a “hegemony of Western bioethics.” Continue reading “Innocent mistake” leads to bioethics article retraction

EMBO takes back Voinnet’s award, investigates other awardee who just lost a Nature Genetics paper

Screen Shot 2016-01-28 at 11.41.20 AMEMBO has taken back an award given to beleaguered plant biologist Olivier Voinnet in 2009, and is investigating a recent grantee who had a paper retracted from Nature Genetics yesterday.

The European Molecular Biology Organization (EMBO) “promotes excellence in the life sciences” in Europe, in part by awarding prizes to promising young scientists. Voinnet and Sonia Melo earned their awards by exhibiting potential as young scientists studying genetics — of plants and cancer, respectively — but now EMBO is skeptical of the papers that formed the basis of their applications.

Melo’s Installation Grant from EMBO was announced just last month, and consists of 50,000 Euros annually for three to five years. She is currently based at the University of Porto, in Portugal.

Voinnet’s problems are well-documented on this blog — 21 corrections, seven retractions, and two investigations. Earlier this week, we reported that the Swiss National Science Foundation had cut off Voinnet’s funding, and banned him for three years. Continue reading EMBO takes back Voinnet’s award, investigates other awardee who just lost a Nature Genetics paper

Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

cov150hAn investigation into a paper that compared infection rates from different types of central lines started with an allegation about a failure to disclose a conflict of interest, and ended up concluding that the science in the paper was flawed.

The 2013 paper — now retracted by the American Journal of Infection Control — suggested a particular kind of connector between the catheter and the patient could reduce some of the notoriously deadly bloodstream infections associated with the procedure, according to a press release that publicized the work. But last year, the journal issued an expression of concern for the paper, noting there were questions about the data. The retraction note reveals an investigation at Georgia Regents University — now known as Augusta University — started looking into undisclosed conflicts of interest in the paper, and ultimately concluded the science was flawed.

Here’s the retraction note, published in the January 1st 2016 issue of the journal, for “Comparison of central line-associated bloodstream infection rates when changing to a zero fluid displacement intravenous needleless connector in acute care settings

Continue reading Investigation of undisclosed conflicts in catheter paper uncovers flawed data, too

What to do when you make a mistake? Advice from authors who’ve been there

cpp-150After a group of researchers noticed an error that affected the analysis of a survey of psychologists working with medical teams to help pediatric patients, they didn’t just issue a retraction — they published a commentary explaining what exactly went wrong.

The error was discovered by a research assistant who was assembling a scientific poster, and noticed the data didn’t align with what was reported in the journal. The error, the authors note, was:

an honest one, a mistake of not reverse coding a portion of the data that none of the authors caught over several months of editing and conference calls. Unfortunately, this error led to misrepresentation and misinterpretation of a subset of the data, impacting the results and discussion.

Needless to say, these authors — who use their “lessons learned” to help other researchers avoid similar missteps — earn a spot in our “doing the right thing” category. The retraction and commentary both appear in Clinical Practice in Pediatric Psychology.

Their first piece of advice in “Retraction experience, lessons learned, and recommendations for clinician researchers” — assume errors will happen, and not vice versa: Continue reading What to do when you make a mistake? Advice from authors who’ve been there

Paper on the adhesiveness of a material doesn’t stick

1-s2.0-S0169433215X00213-cov150hApplied Surface Science has retracted an article that looks at the structure of thin tungsten-titanium coating, because it was submitted without all of the co-authors’ consent.

According to the introduction of the paper, “Structure adhesion and corrosion resistance study of tungsten bisulfide doped with titanium deposited by DC magnetron co-sputtering,” such thin films are “widely used as a surface treatment for optimizing base material properties.”

Here’s the retraction note in full, published in the September issue of the journal:

Continue reading Paper on the adhesiveness of a material doesn’t stick

Swiss funding agency cuts off Voinnet, bans him for 3 years

Olivier Voinnet
Olivier Voinnet

The Swiss National Science Foundation has stopped funding prominent plant scientist Olivier Voinnet, following months of questions about his work that have culminated in multiple retractions and corrections.

The agency confirmed to us that it has also banned Voinnet from seeking funding from the SNSF for three years.

We asked the SNSF the amount of funding Voinnet was receiving from SNSF at the time of this decision. They told us it was 1.25 million Swiss francs, equivalent to roughly the same in U.S. dollars.

By our count, Continue reading Swiss funding agency cuts off Voinnet, bans him for 3 years

Ontario court quashes part of misconduct finding for prominent pair

Sylvia Asa
Sylvia Asa
getpic (1)
Shereen Ezzat

An Ontario court has quashed part of a misconduct finding against a prominent husband and wife team by the University Health Network in Toronto.

Last year, we reported that Sylvia Asa had stepped down from her position as Program Medical Director of the Laboratory Medicine Program at the UHN — the largest hospital diagnostic laboratory in Canada — after an investigation uncovered evidence of falsified data in two papers co-authored with her husband, Shereen Ezzat. Both of their research labs were also suspended as a result. The researchers subsequently appealed the decision.

On Friday Sunday, the Toronto Star reported that the court had set aside the finding of falsification, but upheld a finding of misconduct in the form of material non-compliance. It asked UHN to review the sanctions against both researchers, and cover their legal fees of $20,000.

Here’s the conclusion from the decision:

Continue reading Ontario court quashes part of misconduct finding for prominent pair

Wound healing paper injured beyond repair

no spine minimum. full size. Editor: Jon JEM: Esther RTP: Bryan Nolte TOC image

Errors in the interpretation of some of the data — the result of “procedural flaws” —  are to blame for the retraction of a paper on a way to help skin grow back after injury.

The paper explores a method involving nanofibers. According to the abstract:

In this study, tilapia skin collagen sponge and electrospun nanofibers were developed for wound dressing…the collagen nanofibers stimulated the skin regeneration rapidly and effectively in vivo.

The paper was published January 19, 2015 by ACS Applied Materials and Interfaces, then retracted eight months later, in August. It has not been cited, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note:

Continue reading Wound healing paper injured beyond repair

Science publishes Voinnet’s 19th, 20th, and 21st corrections

351-6271-coverProminent plant biologist Olivier Voinnet has issued three more corrections in this week’s issue of Science.

Collectively, the papers have earned more than 1400 citations, according to Thomson Scientific’s Web of Knowledge.

By our count, he’s now at 21 corrections and seven retractions, following months of questions about his work. He’s been the subject of an investigation that found he “breached his duty of care,” and another which found evidence of scientific misconduct.

One correction goes against the recommendation of the ETH Commission to retract the paper for “well documented intentional manipulations.” According to the correction note, the incorrect figures did not “alter the data in any material way that could be construed to benefit the results and their conclusions.” That correction is the only one of the three for which Voinnet takes full responsibility.

The other two corrections place the responsibility on  Continue reading Science publishes Voinnet’s 19th, 20th, and 21st corrections