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Journal retracts nanoparticles paper for duplicating figures

no spine minimum. full size. Editor: Ann Meares JEM: Diane RTP: Jill Kessler

A paper on nanoparticles that target cancer cells has been retracted for duplicating figures from three other papers.

The articles all share a first author: Manasmita Das, based at the time of the research at the Indian Institute of Technology Kharagpur and the National Institute of Pharmaceutical Education and Research (NIPER). According to her LinkedIn profile, she is currently a postdoc at the University of North Carolina.

The abstract of the 2011 Bioconjugate Chemistry paper explains just what the new nanoparticles would be useful for:

Multifunctional nanoparticles, developed in the course of the study, could selectively target and induce apoptosis to folate-receptor (FR) overexpressing cancer cells with enhanced efficacy as compared to the free drug. In addition, the dual optical and magnetic properties of the synthesized nanoparticles aided in the real-time tracking of their intracellular pathways also as apoptotic events through dual fluorescence and MR-based imaging.

But according to the retraction note, figure duplications “seriously undermine the conclusions presented in the research article.” Here’s more about the source of those duplications from the full note: Continue reading Journal retracts nanoparticles paper for duplicating figures

Researchers plagiarized chapter of doctoral thesis in mol bio paper

mol cell biochemA journal has pulled a paper about the molecular details of different types of adipose tissues after learning the researchers had plagiarized much of a Ph.D. thesis.

The researchers copied from former Ph.D. student Bettina Meissburger’s doctoral thesis in a 2013 paper in Molecular and Cellular Biochemistry. The retraction note for “Adipose stromal-vascular fraction-derived paracrine factors regulate adipogenesis” provides the name of Meissburger’s thesis: Continue reading Researchers plagiarized chapter of doctoral thesis in mol bio paper

Why plagiarism is such a problem for German PhDs: Q&A with Debora Weber-Wulff

Debora Weber-Wulff, c. 2015 Nina Zimmermann
Debora Weber-Wulff, c. 2015 Nina Zimmermann

Why do so many PhD students publishing their medical theses in German resort to brazen plagiarism, even copying from people in their own research groups? We’re pleased to present a Q&A with Debora Weber-Wulff, based at the University of Applied Sciences HTW Berlin in Germany. She recently published a case study for the Council of Europe that shows a surprisingly high number of cases of plagiarism in medical PhD theses submitted to German universities, as well as a few in other European countries. Weber-Wulff is a member of the VroniPlag Wiki, a group of German-language scientists who have been scanning for — and publicly tracking — cases of plagiarism. They’ve published documentations on more than 155 cases so far, and begun investigations on over 200 more, including some very high-profile cases. We talked to Weber-Wulff about why plagiarism is such a problem in German medical PhD programs.

Retraction Watch: You note that German medical dissertations aren’t taken seriously, relative to many other countries. Why is that? Continue reading Why plagiarism is such a problem for German PhDs: Q&A with Debora Weber-Wulff

JACS imaging paper “under editorial review”

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The Journal of the American Chemical Society has issued an expression of concern over “the presentation of results” in a 2014 paper about a new probe for use in imaging.

We haven’t heard back from the journal nor the authors of the paper, so there’s not much we can officially say about what the journal is investigating.

Here’s the text from the expression of concern:
 Continue reading JACS imaging paper “under editorial review”

After 10 years, a whistleblower is vindicated. Here’s why he kept going.

Stefan Franzen
Stefan Franzen

Stefan Franzen doesn’t give up. Ten years ago, he began to suspect the data behind his colleagues’ research about using RNA to make palladium nanoparticles, a potentially valuable tool that ended up as a Science paper. Recently, the National Science Foundation (NSF) decided to cut off funding for Bruce Eaton and Dan Feldheim — currently at the University of Colorado at Boulder — and last week, Science retracted the paper. We talked to Franzen, based at North Carolina State University (NCSU), about his decade-long efforts, and how it feels to be finally vindicated.

Retraction Watch: How did you first begin to suspect the findings by Eaton and Feldheim?

Stefan Franzen: Starting in early 2005, I was collaborating with Drs. Eaton and Feldheim at NCSU, thanks to two joint grants from the W.M. Keck Foundation and NSF. During a group meeting in December of 2005, a graduate student showed electron microscopy data that were inconsistent with the assignment of the particles as palladium. Over time, we kept producing more data that called their findings into question; in April 2006, a postdoc showed that the hexagonal particles could be obtained without RNA. By then, I could see that there was a significant discrepancy between what was written in the articles and what was done and observed in the laboratory.

RW: How did you report your concerns?

Continue reading After 10 years, a whistleblower is vindicated. Here’s why he kept going.

Sparks fly in Finland over misconduct investigation

JEMResearchers in Finland are criticizing an investigation by VTT Technical Research Centre into one of its scientists.

The investigation followed allegations about the VTT’s plasma and serum metabolomics (QBIX) group, previously led by Matej Orešič (who is now based at the Steno Diabetes Center in Gentofte, Denmark) and Tuulia Hyötyläinen. Kai Simons, who conducted an earlier investigation of the group, and the Chancellor Emeritus at the University of Helsinki, have criticized VTT, saying it cut corners in its investigation.

VTT found no evidence of data tampering or falsification in a 2008 paper co-authored by Orešič in the Journal of Experimental Medicine, but said the paper — which has not been corrected or retracted — included some “exaggerated conclusions.” In turn, Orešič and Hyötyläinen filed a complaint for “an alleged violation of good scientific practice” by Simons during the initial investigation. Continue reading Sparks fly in Finland over misconduct investigation

Chemist sues University of Texas (again) to keep PhD

Screen Shot 2016-02-08 at 4.34.25 PMA chemist is suing the University of Texas a second time in an effort to keep the PhD she earned in 2008.

In 2014, school officials revoked Suvi Orr‘s degree after finding it was based, in part, on falsified data. Some of the data were also included in a paper in Organic Letters that was retracted in 2011 after some steps in the chemical synthesis the authors described were not reproducible. Orr, currently working at Pfizer, sued UT, and the school reinstated her degree.

Now, the school is trying to remove it again, according to the lawsuit, filed last week. The lawsuit says the school has scheduled a “hearing” on March 4, during which three undergraduate students and two faculty members will deliberate — “none of whom are qualified to evaluate the scientific evidence being used against S.O.,” the suit says.

Orr has requested a temporary injunction to halt the proceedings, and a hearing has been scheduled for next week, according to the Austin-American Statesman.

The suit argues the school does not have the right to strip Orr’s degree from her: Continue reading Chemist sues University of Texas (again) to keep PhD

Labor pains study brought into this world twice

YJPAI_v16_i6_COVER.inddA group of authors published two articles about one study on pain during childbirth, so one journal is retracting it.

This may seem like a standard case of salami slicing — but this one comes with a nearly 600-word commentary co-authored by the editors of the two journals in question.

The commentary lays out — in a refreshingly transparent way — exactly why the journals came to a joint decision to retract one of the papers:

Continue reading Labor pains study brought into this world twice

Authors used wrong dataset in study on shock therapy, exercise in depression

J psych resA psychiatric journal has pulled a 2014 paper that found electroconvulsive therapy and exercise helped people with depression, after the authors determined they had mistakenly analyzed the wrong data.

According to the retraction notice from the Journal of Psychiatric Research, the researchers had “erroneously analyzed” data from a previous study they had published the year before.

Here’s more from the note for “Electroconvulsive therapy and aerobic exercise training increased BDNF and ameliorated depressive symptoms in patients suffering from treatment-resistant major depressive disorder:” Continue reading Authors used wrong dataset in study on shock therapy, exercise in depression

2014 ORI finding results in retraction of cancer paper with manipulated images

Mol Can TherA paper flagged in an Office of Research Integrity notice more than one year ago has finally been retracted. According to the notice, the paper includes images manipulated by author H. Rosie Xing, a former University of Chicago cancer researcher.

The main conclusions of the paper are affected by the ORI finding, according to the retraction note from Molecular Cancer Therapeutics. But otherwise, the note contains information that was available in the ORI finding, published in December 2014.

“Pharmacologic Inactivation of Kinase Suppressor of Ras1 Sensitizes Epidermal Growth Factor Receptor and Oncogenic Ras-Dependent Tumors to Ionizing Radiation Treatment” has been cited seven times, according to Thomson Scientific’s Web of Knowledge — twice since the ORI finding came out.

The retraction note explains which images were affected by the manipulation:

Continue reading 2014 ORI finding results in retraction of cancer paper with manipulated images