AIDS vaccine fraudster sentenced to nearly 5 years in prison and to pay back $7 million

court case

A researcher who confessed to spiking rabbit blood samples to make the results of an HIV vaccine experiment look better has been sentenced to 57 months of prison time, according to The Des Moines Register.

Dong-Pyou Han has also been ordered to repay more than $7 million to the U.S. National Institutes of Health, and will have three years of supervised release following his prison term.

In December, 2013, the U.S. Office of Research Integrity announced that Han, formerly at Iowa State University (ISU), had faked his results to make an HIV vaccine look more powerful. The faulty data made their way into seven national and international symposia between 2010 and 2012 (resulting in a retracted poster in 2014), along with three grant applications and multiple progress reports. Han agreed to a three-year research ban, and resigned from ISU in October the following year.

The NIH never sent the final $1.38 million grant payment of more than $10 million awarded to Han’s boss, Michael Cho, and ISU returned nearly $500,000 it had received for Han’s salary and other costs.

However, Continue reading AIDS vaccine fraudster sentenced to nearly 5 years in prison and to pay back $7 million

Macchiarini co-author objects to investigation’s misconduct verdict

dr-paolo-macchiarini
Paolo Macchiarini

One of Paolo Macchiarini’s co-authors on a 2011 Lancet paper describing an allegedly groundbreaking procedure to transplant an artificial trachea seeded with stem cells is objecting to a recent investigation that concluded Macchiarini had committed misconduct.

Ola Hermanson, who studies neural stem cells at Karolinska Institutet, argued in a report dated June 29 that the investigation contained “serious flaws and formal errors.”

Hermanson’s lengthy response (uploaded here except for supporting emails) is to the findings of an external review of allegations about Macchiarini’s work, conducted by Bengt Gerdin, of Uppsala University. In regards to the 2011 Lancet paper, Gerdin’s investigation found:

Continue reading Macchiarini co-author objects to investigation’s misconduct verdict

Accounting professor notches 30 (!) retractions after misconduct finding

James Hunton, via Bentley University
James Hunton, via Bentley University

It began with a retraction due to a “misstatement” in November 2012, which led to an investigation that found the first author, James E. Hunton, guilty of misconduct.  Now, the floodgates have opened, and Hunton has 31 retractions under his belt, making him the newest addition to the Retraction Watch leaderboard.

A month after the first retraction in 2012, Hunton resigned from his accounting professorship at Bentley University, citing family and health concerns.

Then, in 2014, a university investigation concluded that Hunton fabricated data in two papers and may have destroyed evidence. The first paper was the one retracted from Accounting Review for a misstatement; the second was retracted from Contemporary Accounting Research in December 2014. Even though the investigation centered around two publications, the university suggested more may be affected:

Continue reading Accounting professor notches 30 (!) retractions after misconduct finding

Weekend reads: LaCour loses job offer; new Science data guidelines; Macchiarini grant funding frozen

booksThis week at Retraction Watch saw us report on thousands of retractions from IEEE, which will have a serious effect on retraction record-keeping, a bizarre case of author impersonation, and a look at dentistry in outer space. Here’s what was happening elsewhere: Continue reading Weekend reads: LaCour loses job offer; new Science data guidelines; Macchiarini grant funding frozen

Weekend reads: Duplication rampant in cancer research?; meet the data detective; journals behaving badly

booksThis week saw us profiled in The New York Times and de Volkskrant, and the introduction of our new staff writer. We also launched The Retraction Watch Leaderboard. Here’s what was happening elsewhere: Continue reading Weekend reads: Duplication rampant in cancer research?; meet the data detective; journals behaving badly

“Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

IAIA team of Harvard and Yale biologists have retracted an Infection and Immunity paper due to data duplication.

After the duplication came to light, the erroneous figures were corrected using original data, but the results affected “some of the manuscript’s conclusions.” An ethics panel subsequently recommended retraction, according to the journal, and the authors agreed.

The paper, “NOD2 Signaling Contributes to Host Defense in the Lungs against Escherichia coli Infection,” analyzed the role of the gene NOD2 in the lung inflammatory response against the bacteria Escherichia coli. It has been cited by 15 other papers, according to Thomson Scientific’s Web of Knowledge.

Figure 2B of the paper was previously corrected in 2012, but the retraction is for data duplication in figures 5F and 6A. Here’s the full retraction note: Continue reading “Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

Pressure to publish not to blame for misconduct, says new study

plosoneA new study suggests that much of what we think about misconduct — including the idea that it is linked to the unrelenting pressure on scientists to publish high-profile papers — is incorrect.

In a new paper out today in PLOS ONE [see update at end of post], Daniele Fanelli, Rodrigo Costas, and Vincent Larivière performed a retrospective analysis of retractions and corrections, looking at the influence of supposed risk factors, such as the “publish or perish” paradigm. The findings appeared to debunk the influence of that paradigm, among others:

Continue reading Pressure to publish not to blame for misconduct, says new study

About-to-be-dismissed lawsuit reveals details of chronic fatigue syndrome-XMRV research fiasco

mikovits
Judy Mikovits

A case filed by chronic fatigue syndrome researcher Judy Mikovits — and about to be dismissed on technical grounds — reveals that Mikovits believes her firing from a research institute was in retaliation for blowing the whistle on activities there.

The suit — which we’ve made available here — was originally filed in November 2014 but is scheduled to be dismissed next week because Mikovits failed to serve the defendant within 120 days, as required under the Federal Rules of Civil Procedure. In it, Mikovits seeks: Continue reading About-to-be-dismissed lawsuit reveals details of chronic fatigue syndrome-XMRV research fiasco

Another “first author has accepted responsibility” retraction from immunity journal

IAIScientists have pulled their 2013 Infection and Immunity paper after a reader noticed duplicated data in three figures, and the first author was “unable to provide the original data used to construct the figures,” according to the journal’s editor-in-chief.

According to the retraction note, “the first author has accepted responsibility for these anomalies” — similar to another recent retraction from the same journal, also due to image duplication reported by a reader (apparently the journal has one or more careful readers).

The paper, “Pseudomonas aeruginosa Outer Membrane Vesicles Modulate Host Immune Responses by Targeting the Toll-Like Receptor 4 Signaling Pathway,” concerns the role of outer membrane vesicles excreted by the bacteria to incite an inflammatory response in mice. It was written by authors at the University of North Dakota, Sichuan University in China, and the University of Chicago, and has been cited six times, according to Thomson Scientific’s Web of Knowledge.

Here’s the complete retraction note:

Continue reading Another “first author has accepted responsibility” retraction from immunity journal

Yet another investigation casts doubt on Förster’s findings; he responds with “outrage”

Jens Förster
Jens Förster

A new group of experts is suggesting there’s something fishy in the body of work of social psychologist Jens Förster.

The University of Amsterdam, Förster’s former employer, commissioned three statistical experts to examine his publication record, looking for signs that the data are not authentic.

Well, they found some signs:

Continue reading Yet another investigation casts doubt on Förster’s findings; he responds with “outrage”