Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘journal of immunology retractions’ Category

Two more retractions for former US prof who altered dozens of images

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Two journals have retracted papers by a biologist who was recently found guilty of misconduct by his former employer, the University of Colorado Denver, bringing the total to five.

The investigation report by UC Denver, which we obtained earlier this year via a public records request, had recommended one of the two newest retractions, which appears in the journal Hepatology. The other retraction, in the Journal of Immunology, was not flagged by the report — which found, among other conclusions, that Almut Grenz had altered multiple values in research that had already been submitted for peer review.

Here’s the notice for the Journal of Immunology paper:

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UCLA lab pulls two papers — one by author who admitted to misconduct

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A lab at the University of California, Los Angeles has retracted two papers for duplicated images.

These retractions — in the Journal of Immunology — represent the second and third retractions for the lab head; he lost another paper after one of his former students confessed to manipulating images.

Although Eriko Suzuki admitted to her actions on PubPeer in 2014, the 2007 Oncogene paper wasn’t retracted until June, 2016, when the journal issued a notice citing “data irregularities.”

Unfortunately, Suzuki’s admission in 2014 wasn’t the end of the troubles for lab head Benjamin Bonavida, who recently issued two additional retractions in the Journal of Immunology, only one of which includes Suzuki as a co-author.

Bonavida told us the university received allegations (he’s not sure from who) that some of the control gels were duplicated; he didn’t agree, but couldn’t produce the original gels to disprove it. We asked if any more retractions were coming from Bonavida, who has since retired from running a lab:

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Five more notices for Duke pulmonary pair brings retraction tally into double digits

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Two retractions and three corrections have appeared for a group of Duke researchers that already have 10+ retractions under their belts.

The reasoning behind them echoes that which we’ve seen before in notices for Michael Foster and Erin Potts-Kant: Following an inquiry from the university, the journals were informed that some of the data or results weren’t reliable, and not all of the experiments could be repeated.

A colleague aware of the case said that researchers are still working to repeat experiments from papers by Potts-Kant and Foster. It is not known how many more papers might be corrected or retracted. Duke University is fully supporting the validation of these experiments, the source told us.

Foster has retired from Duke, a spokesperson for the university confirmed. Read the rest of this entry »

Author objects to retraction for not “faithfully represented” immunology figures

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The Journal of ImmunologyAll but one of the authors of a study about the immune response to H. pylori have agreed to a retraction in The Journal of Immunology, due to two of the paper’s figures not being “faithfully represented.”

Authors of the 2006 paper said they were unable to provide the original unedited scans “due to inadequate archiving dating back almost 10 years.” The authors — with the exception of the first author, Sushil Kumar Pathak, apologized for the error.

The notice, which has been appended to the pdf, reads:

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Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

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American Journal of Physiology - Lung Cellular and Molecular PhysiologyAnother retraction and a correction that retracts two figures — ie, a partial retraction — have been posted for Duke University lung researchers, Erin Potts-Kant and Michael Foster.

These latest notices move the count up to 8.5 retractions for Potts-Kant and 7.5 for Foster (counting the partial retraction as 1/2), along with the correction for both. In both cases and in a familiar note from previous retractions, authors found “potential discrepancies” between two sets of data (partial retraction) and study figures that weren’t “reliable” (retraction).

The retraction comes after the authors discovered problems with three of the study figures. In the corrected paper, the authors were able to validate some of their findings after repeating the experiments, but retracted two of the study figures that they were “unable to verify.”

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Stem cell researcher Jacob Hanna’s correction count updated to 10

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Jacob Hanna

Jacob Hanna

Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.

The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.

First up, a correction to a Cell paper on which Hanna is the first author:

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Exosome pioneer’s paper retracted after investigation finds “multiple” faked figures

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JImmunolThe Journal of Immunology is retracting a 2006 article about the role of exosomes in pregnancy at the behest of the University of Louisville in Kentucky, following a misconduct investigation that “determined multiple figures” in the paper were falsified.

First author Douglas Taylor is a pioneer in exosome biology, having discovered the release of exosomes from tumor cells in the 1970s.

The retracted paper identified “significant quantitative and qualitative differences in released exosomes” in the placentas of fetuses delivered prematurely compared to those delivered without complications at term, particularly relating to immune regulation.  It has been cited 150 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the retraction note (which is paywalled – tsk, tsk): Read the rest of this entry »

Cut and paste and a PC crash: figure manipulations sink two papers

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Two papers by an overlapping group of researchers in Italy have been retracted for manipulated figures.

In late 2013, perennial tipster Clare Francis sent their concerns about several papers, including the two that have been retracted, by authors who frequently publish together. One of the papers, in the Journal of Neurochemistry, is from a team led by Ferdinando Nicoletti; four other papers from the group have been criticized on PubPeer for image manipulation, which he addressed via email with us.

The second retracted paper, from the Journal of Immunology, has shares one author with the first: Patrizia Di Iorio of the University of Chieti, though according to Nicoletti she had no role in preparing the figures.

Here’s the April 2014 notice for “Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways” in the Journal of Neurochemistry. It’s behind a paywall, but the journal has assured us this is against policy and they will be fixing it shortly:
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Immunology researcher with Expression of Concern has cluster of recent retractions, corrections

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j heart lung transplantXia Jiahong, an immunology researcher at Huazhong Science and Technology University in Wuhan, China, who had a paper subject to a fascinating Expression of Concern earlier this month, turns out to have had a few other entries in his retraction and correction record recently.

Here’s a retraction in the January 2014 issue of the Journal of Heart and Lung Transplantation, for “Combined treatment with chemokine receptor 5 blocker and cyclosporine induces prolonged graft survival in a mouse model of cardiac transplantation,” a paper first published in 2010: Read the rest of this entry »

“Sufficient concern” about data prompts retraction of T-cell paper

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journal of immunology 8 15The Journal of Immunology has retracted a 2011 paper on T cell activity after the authors decided they couldn’t stand by the reliability of the work.

The article was titled “Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance.” (On Pubmed the title has the rather ironic precursor “Cutting edge” in front). Here’s the abstract: Read the rest of this entry »