“We were completely shocked:” Plant biologists issue mega-correction

Plant Cell cover

Plant biologists have issued a major correction (what we dub “mega“) after realizing a significant mistake in their experiment.

The 2014 paper shows that a protein known as RAP plays a key role in chloroplast biogenesis. But as Ludwig Maximilians University-based authors Alexandra-Viola Bohne and Laura Kleinknecht continued to do their research, they found an error in the design of primers they used to synthesize the RNA for their experiments — and told us they are concerned other researchers could run into the same problem.

Although the authors considered retracting the paper, since its main conclusion was unaffected, they issued a correction notice, published in April in Plant Cell:

Continue reading “We were completely shocked:” Plant biologists issue mega-correction

Authors pull Mol Cell paper for “inappropriate manipulation” of data

Molecular CellThe authors of a Molecular Cell paper have retracted it due to issues with multiple figures — including one with evidence of “intentional misconduct.”

According to the authors’ institution, IMIM in Barcelona, all co-authors are aware of the retraction. The penultimate author — Antonio García de Herreros — retracted three papers in May from the Journal of Biological Chemistry for reusing images to represent different experiments, and recently corrected multiple figures in a Journal of Cell Science paper over “possible duplications and/or splices.”

Here’s the newest retraction notice: Continue reading Authors pull Mol Cell paper for “inappropriate manipulation” of data

Here’s why this lawyer defends scientists accused of misconduct

Paul S. Thaler
Paul S. Thaler

More scientists are trying to settle accusations of misconduct in court, a trend very familiar to Washington, DC-based lawyer Paul Thaler. Regular readers may recall the name of one of Thaler’s clients — Rakesh Kumar, a scientist at George Washington University who filed an $8 million lawsuit for how the school handled an investigation into his work. He’s also representing Bharat Aggarwal, the subject of an investigation at MD Anderson who has threatened to sue us (and logged his ninth retraction this week). For 25 years, Thaler has been representing scientists embroiled in misconduct proceedings. He spoke to us about his family’s highly pedigreed background in science, and why everyone deserves an advocate.  

Some of your clients have committed misconduct, but you still work to protect their reputations and even help them continue to do research. Why? 

Continue reading Here’s why this lawyer defends scientists accused of misconduct

HIV paper pulled for lack of consent, errors

AIDS JournalA researcher failed to obtain proper consent from HIV patients included in his study about risky sexual behavior, according to the journal that retracted his paper.

The study, based on interviews with 154 men and women living with HIV, concluded that experiencing negative life events correlated with risky sexual behavior. But although the author claimed to have complied with the journal’s standard of consent, the journal disagreed, and retracted the paper in 2014 (we think this case is interesting enough to share with you now). What’s more, according to the journal, the paper contains errors that invalidate its conclusions.

Here’s the notice:

Continue reading HIV paper pulled for lack of consent, errors

Genotyping mistake costs lab two papers and year of work

PNASResearchers are retracting two papers about molecular signalling in plants — including one from the Proceedings of the National Academy of Sciences (PNAS) — after discovering some inadvertent genotyping errors. But that was only after they used the problematic plants for an entire year without realizing they’d made a mistake.

In a pair of refreshingly transparent and detailed notices, the authors explain that the transgenic plants used in the papers included genotyping errors, which invalidated their findings. According to the notices, first author Man-Ho Oh generated the problematic transgenic plants, while corresponding author Steven C. Huber, based at University of Illinois, Urbana-Champaign (UIUC), took responsibility for omitting some critical oversight.

Huber told us that there were only two papers that used the transgenic plants in question, so no other retractions will be forthcoming.

Here’s the notice in PNAS for “Autophosphorylation of Tyr-610 in the receptor kinase BAK1 plays a role in brassinosteroid signaling and basal defense gene expression:”  Continue reading Genotyping mistake costs lab two papers and year of work

Researcher committed misconduct “recklessly,” says investigation

American Journal of Physiology Renal PhsyiologyA physiology journal has retracted a paper after an institutional investigation found that portions of the work had been falsified by the first author.

According to the notice issued by the American Journal of Physiology – Renal Physiology (AJP), the last author initiated the investigation at the University of Houston in Texas, which found the first author — Mousa Abkhezr — to be guilty of falsifying and duplicating images. 

We’ve obtained a copy of the investigation report, which concluded that Abkhezr committed misconduct “recklessly,” and the paper must be retracted. Although the report noted that Abkhezr argued that the problems stemmed from an honest error, the investigation committee ruled that data from the retracted paper cannot be included in his doctoral thesis.

The last author told us there is a separate ongoing “academic honesty enquiry” into Abkhezr’s dissertation. 

Here’s the retraction notice: Continue reading Researcher committed misconduct “recklessly,” says investigation

Publishing needs more science, fewer stories: Q&A with founders of ScienceMatters

rajendran460
Lawrence Rajendran

Ever wish you could just publish an exciting result, without having to wait for the entire string of data that follows in order to tell an entire story, which then gets held up for months by peer review at traditional journals? So do a lot of other researchers, who are working on ways to sidestep those barriers. One new project: ScienceMatters, a publishing platform where scientists can submit single, robust results for relatively quick peer review. We spoke with co-founders Lawrence Rajendran and Mirko Bischofberger about how this new next-generation journal platform works, and why it’s important.

Retraction Watch: You accept “only single observations, properly conducted and robustly validated.” Why did you want to restrict your publications to something so specific, and relatively narrow? Continue reading Publishing needs more science, fewer stories: Q&A with founders of ScienceMatters

Investigation raises questions about top cancer researcher’s work

Journal of Pathology

A prominent pancreatic cancer researcher has lost a meeting abstract and corrected a Nature paper following an institutional investigation.

Queen Mary University of London determined that, in an abstract by Thorsten Hagemann, “elements of the study summarised by this abstract are not reliable.” Hagemann has recently issued a correction to a 2014 Nature paper he co-authored, which also cited the Queen Mary University of London (QMUL) investigation, noting there was “reason to question the provenance of the data.”

Hagemann is currently the medical director of Immodulon Therapeutics, and has long been recognized for his work in the field, including a three-year grant of £180,000 from the Pancreatic Cancer Research Fund in 2013.

Here’s the retraction notice from the The Journal of Pathology, regarding an abstract from the 7th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland: Continue reading Investigation raises questions about top cancer researcher’s work

Weekend reads: Open data’s downsides; do journals serve a purpose?; fraud allegations down in China

booksThe week at Retraction Watch featured news that a religion journal wouldn’t be retracting a paper despite evidence of forgery in the evidence it relied on, and also news that we’re hiring. Here’s what was happening elsewhere: Continue reading Weekend reads: Open data’s downsides; do journals serve a purpose?; fraud allegations down in China

Join our team: Retraction Watch needs a part-time editor

RW logoWe’re so inundated with story ideas and projects, we need some extra help! Specifically, we’re looking for a part-time editor who can be available during specific hours when we need an extra pair of hands.

During that time, you would review tips and write up breaking stories if they arise, as well as edit guest posts and other stories we couldn’t get to during the day. We’re specifically looking for someone who can be available for a fixed block of time, for a total of 12 hours per week.

The specific hours are Continue reading Join our team: Retraction Watch needs a part-time editor