Category: clinical study retractions

Harvard biologist retracts diabetes breakthrough in Cell

2013 probably felt like it was going to be a great year for stem cell biologist Douglas Melton at Harvard. He had published a buzz-worthy paper in Cell about a new way to potentially boost insulin in diabetics, attracting significant media attention, and eventually gathering nearly 200 citations.

But 2016 is closing out on a less positive tone for Melton — today, he and his colleagues are retracting the paper, after multiple labs (including his own) couldn’t reproduce the findings.

Although the lab has itself already published two articles casting doubt on the original findings, Melton told Retraction Watch he chose to retract the paper to ensure there was no confusion about the original paper’s validity: Continue reading Harvard biologist retracts diabetes breakthrough in Cell

Researcher logs three retractions for image duplications — two of which with familiar co-authors

A researcher in Brazil is taking responsibility for accidentally mixing up images in three papers in the Journal of Biological Chemistry. 

The corresponding author on the three papers told us the mistake happened because the studies were conducted simultaneously, and relied on one computer.

There’s a side note to these retractions: The co-author list on two papers includes names that should be fairly well-known to our readers — Mario Saad, the researcher who unsuccessfully sued the American Diabetes Association to stop retractions of his papers, and Rui Curi, a researcher whose legal threats assisted in the shutdown of Science-Fraud.org. This makes Saad’s ninth retraction.

According to the retraction notices, Lício Velloso  — who, like his co-authors, is based at the University of Campinas in São Paulo, Brazil — assembled all the figures. He told Retraction Watch that the authors initially wanted to correct the papers, adding: Continue reading Researcher logs three retractions for image duplications — two of which with familiar co-authors

Co-author of retraction record-holder likely fabricated his own data, analysis shows

In 2012, John Carlisle, a British anesthesiologist, demonstrated conclusively using statistics that Yoshitaka Fujii had faked data in many studies. Fujii — as followers of this blog well know — now holds the record for most retractions by an individual author (183).

Carlisle’s work accomplished two things: It put to rest any doubt that problems with Fujii’s work might have resulted from innocent mistakes, and it gave journals a mathematical tool for conducting investigations into potential cases of misconduct.

Now comes the payoff. In a new paper, Carlisle and another anesthesiologist, John Loadsman, take aim at one of Fujii’s frequent co-authors, Yuhji Saitoh of Yachiyo Medical Center and Tokyo Women’s Medical University in Japan. The pair analyzed data from 31 studies Saitoh published between 1993 and 2012 — including one study that was rejected in 2015 — for a total of 32 papers. Of those, 23 did not include Fujii as an author.

Writing in the journal Anaesthesia, where Carlisle published his first study about Fujii, he and Loadsman state that: Continue reading Co-author of retraction record-holder likely fabricated his own data, analysis shows

Karolinska requests retraction of 2014 Macchiarini paper

Paolo Macchiarini

It has been a tough couple of years for surgeon Paolo Macchiarini, once lauded for pioneering a groundbreaking procedure to transplant tracheas.

After a series of documentaries prompted his former employer, Karolinska Institutet (KI), to reopen a misconduct investigation against him, KI has today released one verdict regarding a 2014 Nature Communications paper: guilty.

KI said it is contacting the journal to request a retraction of the paper, which has already been flagged with an expression of concern.

Here’s more from a release from the institution: Continue reading Karolinska requests retraction of 2014 Macchiarini paper

Catching up: Publisher to pull four papers by retraction record holder flagged years ago

the-laryngoscopeJournals published by Wiley are retracting four papers by Yoshitaka Fujii, the anesthesiology researcher with the most retracted scientific papers.

Retraction Watch readers will be familiar with Fujii’s case: He currently holds the number one spot on our leaderboard with more than 180 retractions, some of which are pending. (That’s nearly twice the number of retractions by the researcher in the #2 spot, Joachim Boldt.) 

Earlier this year, The Breast Journal and The Laryngoscope — both of which are published by Wiley-Blackwell — issued expressions of concern (EOCs) for a total of four papers by Fujii. All four papers were included in a 2012 analysis of 168 of Fujii’s studies by J. B. Carlisle, a consultant anesthetist in the UK, who concluded that the chance of much of Fujii’s data appearing the way it does naturally is

…the chance of selecting one particular atom from all the human bodies on earth.

Now, both journals are retracting the papers. 

A Wiley spokesperson told us: Continue reading Catching up: Publisher to pull four papers by retraction record holder flagged years ago

Bone researcher with lifetime funding ban earns third retraction

via WCH

A researcher who received a lifetime funding ban for misconduct from a Canadian agency has logged her third retraction, after a re-analysis of her work unveiled “serious inconsistencies.”

In July, the Canadian Institutes of Health Research (CIHR) released a report about Sophie Jamal, following an investigation by her former employer, The Women’s College Hospital in Toronto, Canada. The probe concluded that Jamal had manipulated data, which resulted in her being banned from CIHR funding for life, and the retraction of a study in The Journal of the American Medical Association.

After that retraction, researchers that made up the the Canadian Multicentre Osteoporosis Study Group (CaMos) decided to take a second look at Jamal’s work. In August, we reported on a retraction that came out of that examination, in the American Journal of Kidney Diseases (AJKD). At the time, a senior researcher from the group told us the group had also requested another journal retract a CaMos paper. 

Now, that other retraction has appeared. Here’s the retraction notice Osteoporosis International issued earlier this month: Continue reading Bone researcher with lifetime funding ban earns third retraction

Oops: Supposedly untreated cancer patients had surgery, after all

gmrThe first author of a 2016 paper has retracted it after realizing that all the lung cancer patients that were supposed to have been untreated did, in fact, have surgery to remove their tumors. 

Zhao Kai, the study’s first author from the Qilu Hospital of Shandong University and Zibo Central Hospital (both in China), took full responsibility for the error.

Here’s the retraction notice, published last month in Genetics and Molecular Research: Continue reading Oops: Supposedly untreated cancer patients had surgery, after all

High-profile Science paper retracted for misconduct

Science has retracted a high-profile immunology paper after a probe concluded the corresponding author had committed misconduct.

The paper — which initially caught media attention for suggesting a protein could help boost the immune system’s ability to fight off tumors — has been under a cloud of suspicion since last year, when the journal tagged it with an expression of concern, citing a university investigation.

That investigation — at Imperial College London — has concluded that the paper contained problematic figures that were the result of research misconduct. All were prepared by last and corresponding author Philip Ashton-Rickardt, who took full responsibility. Even though the paper was published in 2015, some original blots and accompanying details have disappeared.

Today, the journal released a retraction notice: Continue reading High-profile Science paper retracted for misconduct

Journal pulls cancer paper that used others’ data; authors MIA

A journal has retracted a paper after a reader pointed out some of the data looked familiar — and the authors never responded to the allegations.

According to the retraction notice in the International Journal of Molecular Medicine, the reader showed the journal that the histological data in two of the figures were from another published paper by different researchers. But when the journal contacted the authors on several occasions, they didn’t hear back. 

Here’s the retraction notice: Continue reading Journal pulls cancer paper that used others’ data; authors MIA

Dear peer reviewer, you stole my paper: An author’s worst nightmare

“Deeply disturbing,” “heinous intellectual theft,” erosion of the “public’s trust in medical research:” These are just a few words used to describe a rare type of plagiarism reported in this week’s Annals of Internal Medicine.

Although we’ve only documented a few cases where peer reviewers steal material from manuscripts and pass them off as their own, it does happen, and it’s a fear of many authors. What we’ve never seen is a plagiarized author publish a letter to the reviewer who stole his work. But after Michael Dansinger of Tufts Medical Center realized a paper he’d submitted to Annals of Internal Medicine that had been rejected was republished, and the journal recognized one of the reviewers among the list of co-authors, it published a letter from Dansinger to the reviewer, along with an editorial explaining what happened.

The letter and editorial identify the paper containing the stolen material — now retracted — but don’t name the reviewer responsible. Still, the articles are deeply personal. As Dansinger writes in “Dear Plagiarist: A Letter to a Peer Reviewer Who Stole and Published Our Manuscript as His Own,” the reviewer took much more than just a manuscript:

Continue reading Dear peer reviewer, you stole my paper: An author’s worst nightmare