Category: basic life sciences retractions

MIT lab retracts Cell synapse tagging paper for falsification or fabrication

cell feb 2013A rising star at MIT has retracted a paper after an investigation found that her former postdoc had “falsified or fabricated figures.”

Alice Ting, winner of an NIH Directors Pioneer Award and named one of Technology Review’s “Innovators Under 35,” published the paper, “Imaging Activity-Dependent Regulation of Neurexin-Neuroligin Interactions Using trans-Synaptic Enzymatic Biotinylation,” in Cell in 2010 along with Amar Thyagarajan.

The notice is refreshingly detailed given the circumstances: Continue reading MIT lab retracts Cell synapse tagging paper for falsification or fabrication

A retracted Cell paper reappears elsewhere, sans author who didn’t sign retraction notice

acta neuropathologicaOne of the things we try to do here at Retraction Watch is keep tabs on retracted work that appears again the literature. We did that twice in one day last year, once with a paper about chimps that was retracted from Biology Letters and ended up in the Journal of Human Evolution, and then again with a PLOS ONE paper on on “longevity genes” that had been retracted from Science.

Today, we have another case. Continue reading A retracted Cell paper reappears elsewhere, sans author who didn’t sign retraction notice

Author retracts FASEB Journal paper for data reuse

fasebThe FASEB Journal has retracted a 2012 paper by a group from the University of Alabama, Birmingham (UAB), looking at the role of a tumor-suppressing micro-RNA in pulmonary fibrosis. The retraction suggests the provenance of the data are in question, and we learned details of what went wrong.

Here’s the notice, which, sadly, is behind a $12-per-day paywall: Continue reading Author retracts FASEB Journal paper for data reuse

First author of recently retracted paper has another corrected, in J Ag Food Chem

jafcau_v061i004.inddA paper that shares a first author with a paper retracted in December has been corrected.

Late last year, we reported on a retraction in Antioxidants & Redox Signaling (ARDS) by Indika Edirisinghe, who was at the University of Rochester when the original paper was published, and colleagues. On January 17, the Journal of Agricultural and Food Chemistry published a correction to “Effect of Black Currant Anthocyanins on the Activation of Endothelial Nitric Oxide Synthase (eNOS) in Vitro in Human Endothelial Cells,” on which Edirisinghe is also first author.

His affiliation on that paper, originally published in July 2011, is the Illinois Institute of Technology. Here’s the correction: Continue reading First author of recently retracted paper has another corrected, in J Ag Food Chem

“Unreliable” findings fell TB gene study in PLOS ONE

plosoneHere’s a nice example of how science should work.

A team of Swiss microbiologists has retracted their 2012 paper in PLoS One on the genetics of the TB mycobacterium after learning that the fusion protein they thought they’d used in their study was in fact a different molecule.

Here’s the retraction notice for the article, “A β-lactamase based reporter system for ESX dependent protein translocation in mycobacteria,” which has been cited once, according to Thomson Scientific’s Web of Knowledge: Continue reading “Unreliable” findings fell TB gene study in PLOS ONE

Study finds many authors aren’t sharing data when they publish — and leads to a PLOS ONE retraction

clinical chemistryA new study in Clinical Chemistry paints an alarming picture of how often scientists deposit data that they’re supposed to — but perhaps not surprisingly, papers whose authors did submit such data scored higher on a quality scale than those whose authors didn’t deposit their data.

Ken Witwer, a pathobiologist at Hopkins, was concerned that a lot of studies involving microarray-based microRNA (miRNA) weren’t complying with Minimum Information About a Microarray Experiment (MIAME) standards supposedly required by journals. So he looked at 127 such papers published between July 2011 and April 2012 in journals including PLOS ONE, the Journal of Biological Chemistry, Blood, and Clinical Chemistry, assigning each one a quality score and checking whether the authors had followed guidelines.

What he uncovered wasn’t pretty — and has already led to a retraction. From the abstract: Continue reading Study finds many authors aren’t sharing data when they publish — and leads to a PLOS ONE retraction

University of Wisconsin neuroscientist faked data in two papers: ORI

adibhatla
Rao Adibhatla, via University of Wisconsin

A University of Wisconsin neuroscience researcher falsified “Western blot images as well as quantitative and statistical data” in two NIH-supported papers and three unfunded grant applications, the U.S. Office of Research Integrity (ORI) has found.

As first reported by the Milwaukee Journal-Sentinel and then The Scientist, Rao M. Adibhatla has agreed to retract the two papers, in the Journal of Biological Chemistry and Brain Research: Continue reading University of Wisconsin neuroscientist faked data in two papers: ORI

Curi-us: Author whose lawyers threatened Science Fraud corrects a paper the site criticized

curi
Rui Curi

A few weeks ago, we reported on the shutdown of Science-Fraud.org, a site dedicated to highlighting problems with scientific papers, thanks to legal threats. At the same time, we noted that Rui Curi, one of the authors whose work had been questioned — and whose lawyers had sent the site a cease-and-desist letter — ended up retracting a paper the site had questioned.

Now, Curi has corrected another paper that featured on Science-Fraud.org. Here’s the notice: for “Comparative toxicity of oleic and linoleic acid on human lymphocytes,” which was originally published in Life Science in 2006: Continue reading Curi-us: Author whose lawyers threatened Science Fraud corrects a paper the site criticized

Clare Francis scores a bullseye: Journal of Cell Biology paper retracted for image manipulation

jcbIf you’re a journal editor or publisher, there’s a good chance your email inbox has seen its share of emails from “Clare Francis,” who has been crusading against text and image duplication in papers for some years now. Some editors have grown quite weary of those emails, sometimes because they don’t want to deal with anonymous whistleblowers, and sometimes because they have found Clare’s claims to be without merit.

But the Journal of Cellular Biology is one journal that has apparently continued to take them seriously. Today, they retract “Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion,” a 2006 paper about which Francis first raised concerns in early November. Here’s the notice, one of those wonderfully detailed ones that make us squeal like schoolgirls meeting the Beatles: Continue reading Clare Francis scores a bullseye: Journal of Cell Biology paper retracted for image manipulation

Neuroscientists retract Cell autism model paper for “improperly assembled” figures

cell 1-17-13A group of authors have retracted a Cell paper describing a mouse model of autism because of image problems.

The senior author on the paper — there were 22 altogether — is Paul Worley of Johns Hopkins. Here’s the notice for “Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism:” Continue reading Neuroscientists retract Cell autism model paper for “improperly assembled” figures