Category: basic life sciences retractions

“Unreliable” findings fell TB gene study in PLOS ONE

plosoneHere’s a nice example of how science should work.

A team of Swiss microbiologists has retracted their 2012 paper in PLoS One on the genetics of the TB mycobacterium after learning that the fusion protein they thought they’d used in their study was in fact a different molecule.

Here’s the retraction notice for the article, “A β-lactamase based reporter system for ESX dependent protein translocation in mycobacteria,” which has been cited once, according to Thomson Scientific’s Web of Knowledge: Continue reading “Unreliable” findings fell TB gene study in PLOS ONE

Study finds many authors aren’t sharing data when they publish — and leads to a PLOS ONE retraction

clinical chemistryA new study in Clinical Chemistry paints an alarming picture of how often scientists deposit data that they’re supposed to — but perhaps not surprisingly, papers whose authors did submit such data scored higher on a quality scale than those whose authors didn’t deposit their data.

Ken Witwer, a pathobiologist at Hopkins, was concerned that a lot of studies involving microarray-based microRNA (miRNA) weren’t complying with Minimum Information About a Microarray Experiment (MIAME) standards supposedly required by journals. So he looked at 127 such papers published between July 2011 and April 2012 in journals including PLOS ONE, the Journal of Biological Chemistry, Blood, and Clinical Chemistry, assigning each one a quality score and checking whether the authors had followed guidelines.

What he uncovered wasn’t pretty — and has already led to a retraction. From the abstract: Continue reading Study finds many authors aren’t sharing data when they publish — and leads to a PLOS ONE retraction

University of Wisconsin neuroscientist faked data in two papers: ORI

adibhatla
Rao Adibhatla, via University of Wisconsin

A University of Wisconsin neuroscience researcher falsified “Western blot images as well as quantitative and statistical data” in two NIH-supported papers and three unfunded grant applications, the U.S. Office of Research Integrity (ORI) has found.

As first reported by the Milwaukee Journal-Sentinel and then The Scientist, Rao M. Adibhatla has agreed to retract the two papers, in the Journal of Biological Chemistry and Brain Research: Continue reading University of Wisconsin neuroscientist faked data in two papers: ORI

Curi-us: Author whose lawyers threatened Science Fraud corrects a paper the site criticized

curi
Rui Curi

A few weeks ago, we reported on the shutdown of Science-Fraud.org, a site dedicated to highlighting problems with scientific papers, thanks to legal threats. At the same time, we noted that Rui Curi, one of the authors whose work had been questioned — and whose lawyers had sent the site a cease-and-desist letter — ended up retracting a paper the site had questioned.

Now, Curi has corrected another paper that featured on Science-Fraud.org. Here’s the notice: for “Comparative toxicity of oleic and linoleic acid on human lymphocytes,” which was originally published in Life Science in 2006: Continue reading Curi-us: Author whose lawyers threatened Science Fraud corrects a paper the site criticized

Clare Francis scores a bullseye: Journal of Cell Biology paper retracted for image manipulation

jcbIf you’re a journal editor or publisher, there’s a good chance your email inbox has seen its share of emails from “Clare Francis,” who has been crusading against text and image duplication in papers for some years now. Some editors have grown quite weary of those emails, sometimes because they don’t want to deal with anonymous whistleblowers, and sometimes because they have found Clare’s claims to be without merit.

But the Journal of Cellular Biology is one journal that has apparently continued to take them seriously. Today, they retract “Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion,” a 2006 paper about which Francis first raised concerns in early November. Here’s the notice, one of those wonderfully detailed ones that make us squeal like schoolgirls meeting the Beatles: Continue reading Clare Francis scores a bullseye: Journal of Cell Biology paper retracted for image manipulation

Neuroscientists retract Cell autism model paper for “improperly assembled” figures

cell 1-17-13A group of authors have retracted a Cell paper describing a mouse model of autism because of image problems.

The senior author on the paper — there were 22 altogether — is Paul Worley of Johns Hopkins. Here’s the notice for “Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism:” Continue reading Neuroscientists retract Cell autism model paper for “improperly assembled” figures

University of Lisbon investigation that spawned neuroscience retractions found no evidence of misconduct

j neuroscienceYesterday, we reported on two retractions in the Journal of Neuroscience whose notices referred to a University of Lisbon report that had determined there was  “substantial data misrepresentation” in the original articles.  The notice didn’t say anything about misconduct, but when we see “misrepresentation,” we tend to think — as do many others — that there had been funny business.

But we heard back this morning from the senior author of the study, Ana M. Sebastião, and there’s a lot more to this story. It turns out that the University of Lisbon committee that wrote the report concluded, unanimously, that Continue reading University of Lisbon investigation that spawned neuroscience retractions found no evidence of misconduct

University of Lisbon finds “substantial data misrepresentation;” two Journal of Neuroscience papers retracted

j neuroscienceA University of Lisbon investigation has prompted two retractions in the Journal of Neuroscience.

The papers share a few authors, including senior author Ana M. Sebastião. Here’s the notice for the first paper: Continue reading University of Lisbon finds “substantial data misrepresentation;” two Journal of Neuroscience papers retracted

Leading cancer researcher retracts 2003 paper for “inappropriate presentation”

cancer cellOne of the world’s leading cancer researchers, MIT’s Robert Weinberg, has retracted a decade-old paper after finding out it contained errors.

Here’s the notice for “Ras Modulates Myc Activity to Repress Thrombospondin-1 Expression and Increase Tumor Angiogenesis,” a paper originally published in Cancer Cell in 2003: Continue reading Leading cancer researcher retracts 2003 paper for “inappropriate presentation”

First retraction for Eric Smart, who faked dozens of images, appears in PNAS

Eric J. Smart, via U Kentucky
Eric J. Smart, via U Kentucky

Eric Smart, who as we reported in November was sanctioned by the Office of Research Integrity (ORI) for faking dozens of images in ten papers and seven grants over the past decade, has had his first retraction.

Here’s the December 24 notice, from PNAS: Continue reading First retraction for Eric Smart, who faked dozens of images, appears in PNAS